Patent · US10266698B2 · B2 · US
Colorant compounds derived from genipin or genipin containing materials
- (11) Publication number
- US10266698B2
- (21) Application number
- 15/807,435
- (22) Filing date
- 2017-11-08
- (30) Priority date
- 2013-05-22
- (43) Publication date
- 2019-04-23
- (45) Date of grant
- 2019-04-23
- (52) CPC
- C09B Organic dyes or closely-related compounds for producing dyes {, e.g. pigments}; mordants; lakes: 61/00, 23/04, 67/0034, 67/0096, 69/10
- A23L Foods, foodstuffs or non-alcoholic beverages, not otherwise provided for; preparation or treatment thereof: 5/43
- A23V Indexing scheme relating to foods, foodstuffs or non-alcoholic beverages and lactic or propionic acid bacteria used in foodstuffs or food preparation: 2002/00
- A61K Preparations for medical, dental or toiletry purposes: 2800/30, 47/34, 8/84
- (73) Assignee
- ECOFLORA S A S
- (54) Title
- Colorant compounds derived from genipin or genipin containing materials
- (57) Abstract
The present disclosure provides colorant compounds and methods of isolation of the colorant compounds derived from a reaction of genipin and an amine. The colorant compositions comprise purified compounds (e.g., a purified polymer or a purified dimer) obtained from multiple fractioning by chromatography of the reaction resulting material. The purified polymer or dimer can be used as a colorant by itself or in combination with another colorant for imparting color to a food, a drug, a cosmetic, a medical device, and textile products.
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Claims (24)
- A method of preparing of a black colorant composition comprising (a) preparing a juice extract from Genipa americana fruit, wherein the juice extract is raw liquid Genipa americana juice; (b) mixing the juice extract and proline to form a mixture; and (c) isolating a black colorant composition from the mixture of (b).
- A black colorant composition prepared by the method of claim 1.
- A method of preparing of a green colorant composition comprising (a) preparing a juice extract from Genipa americana fruit, wherein the juice extract is raw liquid Genipa americana juice; (b) mixing the juice extract and tryptophan to form a mixture; and (c) isolating a green colorant composition from the mixture of (b).
- A green colorant composition prepared by the method of claim 3.
- A food product comprising a food item and the black colorant composition of claim 2.
- The food product of claim 5, wherein the food item is a solid food item or a liquid food item.
- The food product of claim 6, wherein the food item is a beverage.
- A food product comprising a food item and the green colorant composition of claim 4.
- The food product of claim 8, wherein the food item is a solid food item or a liquid food item.
- The food product of claim 9, wherein the food item is a beverage.
- A drug or nutraceutical product comprising a drug or nutraceutical and the green colorant composition of claim 4.
- The drug or nutraceutical product of claim 11, wherein the drug or nutraceutical is in a dosage form selected from the group consisting of tablets, gel caps, beads, pellets, pills, dragees, lozenges, ointments, capsules, powders, liquids, gels, syrups, slurries, and suspensions.
- A cosmetic product comprising the green colorant composition of claim 4.
- The method of claim 1, further comprising heating the mixture of juice extract and proline after step (b).
- The method of claim 3, further comprising heating the mixture of juice extract and tryptophan after step (b).
- The method of claim 1, further comprising purifying the black colorant composition of (c).
- The method of claim 3, further comprising purifying the green colorant composition of (c).
- The method of claim 3, wherein no additional ingredients are added to the raw liquid Genipa americana juice prior to step (b).
- The method of claim 3, wherein the tryptophan is in an isolated form.
- The method of claim 3, wherein the tryptophan is mixed with the juice extract in an equimolar amount relative to the amount of genepin in the juice extract.
- The method of claim 1, wherein no additional ingredients are added to the raw liquid Genipa americana juice prior to step (b).
- The method of claim 1, wherein the proline is in an isolated form.
- The method of claim 1, wherein the proline is mixed with the juice extract in an equimolar amount relative to the amount of genepin in the juice extract.
- A drug or nutraceutical product comprising a drug or nutraceutical and the black colorant composition of claim 2.
Citations (40)
- CN101104745A
- CN101735642A
- CN101831469A
- CN101899484A
- CN102014670A
- CN102171292A
- CN102174608A
- CN102448327A
- CN104685004A
- JPH05339134A
- JPH07310023A
- JPH08301739A
- JPS5253932A
- JPS5253934A
- JPS55164625A
- JPS57209958A
- JPS5781466A
- JPS6147167A
- JPS6422820A
- US2005008746A1
- US2008260668A1
- US2009223000A1
- US2009246343A1
- US2010083448A1
- US2012114772A1
- US2013115252A1
- US2013202703A1
- US2013345427A1
- US2016376442A1
- US4247698A
- US4347356A
- US4878921A
- US7279189B2
- US7649014B2
- US7927637B2
- US9376569B2
- WO2009120579A1
- WO2012043173A1
- WO2014001910A1
- WO2014188275A2
Record as JSON
{
"publication_number": "US10266698B2",
"country": "US",
"kind": "B2",
"title": "Colorant compounds derived from genipin or genipin containing materials",
"abstract": "The present disclosure provides colorant compounds and methods of isolation of the colorant compounds derived from a reaction of genipin and an amine. The colorant compositions comprise purified compounds (e.g., a purified polymer or a purified dimer) obtained from multiple fractioning by chromatography of the reaction resulting material. The purified polymer or dimer can be used as a colorant by itself or in combination with another colorant for imparting color to a food, a drug, a cosmetic, a medical device, and textile products.",
"claims": [
"1. A method of preparing of a black colorant composition comprising (a) preparing a juice extract from Genipa americana fruit, wherein the juice extract is raw liquid Genipa americana juice; (b) mixing the juice extract and proline to form a mixture; and (c) isolating a black colorant composition from the mixture of (b).",
"2. A black colorant composition prepared by the method of claim 1.",
"3. A method of preparing of a green colorant composition comprising (a) preparing a juice extract from Genipa americana fruit, wherein the juice extract is raw liquid Genipa americana juice; (b) mixing the juice extract and tryptophan to form a mixture; and (c) isolating a green colorant composition from the mixture of (b).",
"4. A green colorant composition prepared by the method of claim 3.",
"5. A food product comprising a food item and the black colorant composition of claim 2.",
"6. The food product of claim 5, wherein the food item is a solid food item or a liquid food item.",
"7. The food product of claim 6, wherein the food item is a beverage.",
"8. A food product comprising a food item and the green colorant composition of claim 4.",
"9. The food product of claim 8, wherein the food item is a solid food item or a liquid food item.",
"10. The food product of claim 9, wherein the food item is a beverage.",
"11. A drug or nutraceutical product comprising a drug or nutraceutical and the green colorant composition of claim 4.",
"12. The drug or nutraceutical product of claim 11, wherein the drug or nutraceutical is in a dosage form selected from the group consisting of tablets, gel caps, beads, pellets, pills, dragees, lozenges, ointments, capsules, powders, liquids, gels, syrups, slurries, and suspensions.",
"13. A cosmetic product comprising the green colorant composition of claim 4.",
"14. The method of claim 1, further comprising heating the mixture of juice extract and proline after step (b).",
"15. The method of claim 3, further comprising heating the mixture of juice extract and tryptophan after step (b).",
"16. The method of claim 1, further comprising purifying the black colorant composition of (c).",
"17. The method of claim 3, further comprising purifying the green colorant composition of (c).",
"18. The method of claim 3, wherein no additional ingredients are added to the raw liquid Genipa americana juice prior to step (b).",
"19. The method of claim 3, wherein the tryptophan is in an isolated form.",
"20. The method of claim 3, wherein the tryptophan is mixed with the juice extract in an equimolar amount relative to the amount of genepin in the juice extract.",
"21. The method of claim 1, wherein no additional ingredients are added to the raw liquid Genipa americana juice prior to step (b).",
"22. The method of claim 1, wherein the proline is in an isolated form.",
"23. The method of claim 1, wherein the proline is mixed with the juice extract in an equimolar amount relative to the amount of genepin in the juice extract.",
"24. A drug or nutraceutical product comprising a drug or nutraceutical and the black colorant composition of claim 2."
],
"cpc": [
"C09B 61/00",
"A23L 5/43",
"A23V 2002/00",
"A61K 2800/30",
"A61K 47/34",
"A61K 8/84",
"C09B 23/04",
"C09B 67/0034",
"C09B 67/0096",
"C09B 69/10"
],
"assignees": [
"ECOFLORA S A S"
],
"filing_date": "2017-11-08",
"publication_date": "2019-04-23",
"grant_date": "2019-04-23",
"priority_date": "2013-05-22",
"application_number": "US-201715807435-A",
"family_id": "51626090",
"citations": [
"CN101104745A",
"CN101735642A",
"CN101831469A",
"CN101899484A",
"CN102014670A",
"CN102171292A",
"CN102174608A",
"CN102448327A",
"CN104685004A",
"JPH05339134A",
"JPH07310023A",
"JPH08301739A",
"JPS5253932A",
"JPS5253934A",
"JPS55164625A",
"JPS57209958A",
"JPS5781466A",
"JPS6147167A",
"JPS6422820A",
"US2005008746A1",
"US2008260668A1",
"US2009223000A1",
"US2009246343A1",
"US2010083448A1",
"US2012114772A1",
"US2013115252A1",
"US2013202703A1",
"US2013345427A1",
"US2016376442A1",
"US4247698A",
"US4347356A",
"US4878921A",
"US7279189B2",
"US7649014B2",
"US7927637B2",
"US9376569B2",
"WO2009120579A1",
"WO2012043173A1",
"WO2014001910A1",
"WO2014188275A2"
]
}
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