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Patent · US10729530B2 · B2 · US

Endovascular device for sensing and or stimulating tissue

(11) Publication number
US10729530B2
(21) Application number
15/955,412
(22) Filing date
2018-04-17
(30) Priority date
2015-10-20
(43) Publication date
2020-08-04
(45) Date of grant
2020-08-04
(51) IPC
A61B 5/296; A61F 2/06; A61B 5/00; A61F 2/90
(52) CPC
  • A61F Filters implantable into blood vessels; prostheses; devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents; orthopaedic, nursing or contraceptive devices; fomentation; treatment or protection of eyes or ears; bandages, dressings or absorbent pads; first-aid kits: 2/06, 2/72, 2/88, 2/90, 2230/0067, 2250/0001, 4/00
  • A61B Diagnosis; surgery; identification: 2505/09, 5/0215, 5/04001, 5/042, 5/0478, 5/24, 5/291, 5/293, 5/388, 5/4052, 5/4064, 5/4836, 5/6862, 5/6877, 5/7207
  • A61N Electrotherapy; magnetotherapy; radiation therapy; ultrasound therapy: 1/0529, 1/0531, 1/0539, 1/36103, 1/36128, 1/37205, 1/37211
(72) Inventors
Nicholas Lachlan OPIE; Thomas James Oxley; Gil Simon RIND; Stephen Michael RONAYNE; Sam Emmanuel JOHN
(54) Title
Endovascular device for sensing and or stimulating tissue
(57) Abstract

Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.

Full text
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Claims (11)

  1. A method of recording of neural information or stimulation of neurons of a patient, the method comprising: receiving a signal representative of neural activity from a stent having an electrode positioned in a vessel of the patient, where the stent comprises a first strut having a first conductive path and a second strut having a second conductive path, where the first conductive path is embedded in the first strut, where the second conductive path is embedded in the first strut and in the second strut, where the first conductive path and the second conductive path extend between a first end and a second end of the first strut, and where the first and second conductive paths are independent data channels, the method further comprising transmitting or receiving first data via the first conductive path and transmitting or receiving second data different from the first data via the second conductive path; generating data representing said activity using the signal; transmitting said data to a control unit; generating a control signal from the control unit; and transmitting the control signal to an apparatus coupled to the patient.
  2. The method of claim 1, where the stent comprises electrodes, where the electrodes are arranged around a circumference of the stent, where the stent has a contracted configuration and an expanded configuration, where when the stent is in the contracted configuration, the first conductive path and the second conductive path are separated by a first distance, where when the stent is in the expanded configuration, the first conductive path and the second conductive path are separated by a second distance, and where the second distance is greater than the first distance.
  3. The method of claim 1, where the first strut has a first embedded electrode where the first conductive path is exposed, and where the second strut has a second embedded electrode where the second conductive path is exposed.
  4. The method of claim 3, where the first embedded electrode is located where the first strut intersects the second strut.
  5. The method of claim 1, where the stent is positioned in a vessel selected from either a vessel in a superior sagittal sinus or a branching cortical vein.
  6. The method of claim 1, where the device is positioned in a vessel located adjacent to a visual cortex of a patient.
  7. The method of claim 1, wherein the vessel is located in a muscle for direct muscular stimulation or recording.
  8. The method of claim 1, wherein the vessel adjacent to a peripheral nerve for stimulation or recording.
  9. The method of claim 1, wherein the vessel is adjacent to a sympathetic or parasympathetic nerve.
  10. The method of claim 1, where the signal travels from the first electrode through the first conductive path and through a lead coupled to the first conductive path to the control unit.
  11. The method of claim 1, where at least one of the struts has three embedded conductive paths.

Description

This application claims priority to U.S. Provisional Application No. 62/486,851 filed Apr. 18, 2017 which is incorporated herein by reference in its entirety for all purposes. This application is also a continuation-in-part of International Patent Application No. PCT/US2016/057768 filed Oct. 19, 2016, now published as WO2017/070252, which is a non-provisional application of Australian Provisional Application 2015904302 filed Oct. 20, 2015, of Australian Provisional Application 2015905045 filed Dec. 4, 2015, and of U.S. Provisional Application No. 62/379,625 filed Aug. 25, 2016.

The present invention relates to a medical device for implantation into a blood vessel of an animal.

Any discussion of document, devices, acts or knowledge in this specification is included to explain the context of the invention. It should not be taken as an admission that any of the material forms a part of the prior art base or the common general knowledge in the relevant art in Australia or elsewhere on or before the priority date of the disclosure and broad consistory statements herein.

In the United States alone, nearly two million people suffer from various neuromuscular disorders where control of limbs is severely impaired. In many of these patients, however, the portion of the brain responsible for movement remains intact, and it is disease and trauma to the spinal cord, nerves and muscles that limit mobility, function and independence. For these people, the ability to restore lost control at even a rudimentary level could lead to a greatly improved quality of life.

Citations (111)

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Record as JSON
{
  "publication_number": "US10729530B2",
  "country": "US",
  "kind": "B2",
  "title": "Endovascular device for sensing and or stimulating tissue",
  "abstract": "Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.",
  "claims": [
    "1. A method of recording of neural information or stimulation of neurons of a patient, the method comprising: receiving a signal representative of neural activity from a stent having an electrode positioned in a vessel of the patient, where the stent comprises a first strut having a first conductive path and a second strut having a second conductive path, where the first conductive path is embedded in the first strut, where the second conductive path is embedded in the first strut and in the second strut, where the first conductive path and the second conductive path extend between a first end and a second end of the first strut, and where the first and second conductive paths are independent data channels, the method further comprising transmitting or receiving first data via the first conductive path and transmitting or receiving second data different from the first data via the second conductive path; generating data representing said activity using the signal; transmitting said data to a control unit; generating a control signal from the control unit; and transmitting the control signal to an apparatus coupled to the patient.",
    "2. The method of claim 1, where the stent comprises electrodes, where the electrodes are arranged around a circumference of the stent, where the stent has a contracted configuration and an expanded configuration, where when the stent is in the contracted configuration, the first conductive path and the second conductive path are separated by a first distance, where when the stent is in the expanded configuration, the first conductive path and the second conductive path are separated by a second distance, and where the second distance is greater than the first distance.",
    "3. The method of claim 1, where the first strut has a first embedded electrode where the first conductive path is exposed, and where the second strut has a second embedded electrode where the second conductive path is exposed.",
    "4. The method of claim 3, where the first embedded electrode is located where the first strut intersects the second strut.",
    "5. The method of claim 1, where the stent is positioned in a vessel selected from either a vessel in a superior sagittal sinus or a branching cortical vein.",
    "6. The method of claim 1, where the device is positioned in a vessel located adjacent to a visual cortex of a patient.",
    "7. The method of claim 1, wherein the vessel is located in a muscle for direct muscular stimulation or recording.",
    "8. The method of claim 1, wherein the vessel adjacent to a peripheral nerve for stimulation or recording.",
    "9. The method of claim 1, wherein the vessel is adjacent to a sympathetic or parasympathetic nerve.",
    "10. The method of claim 1, where the signal travels from the first electrode through the first conductive path and through a lead coupled to the first conductive path to the control unit.",
    "11. The method of claim 1, where at least one of the struts has three embedded conductive paths."
  ],
  "description_excerpt": "This application claims priority to U.S. Provisional Application No. 62/486,851 filed Apr. 18, 2017 which is incorporated herein by reference in its entirety for all purposes. This application is also a continuation-in-part of International Patent Application No. PCT/US2016/057768 filed Oct. 19, 2016, now published as WO2017/070252, which is a non-provisional application of Australian Provisional Application 2015904302 filed Oct. 20, 2015, of Australian Provisional Application 2015905045 filed Dec. 4, 2015, and of U.S. Provisional Application No. 62/379,625 filed Aug. 25, 2016.\n\nThe present invention relates to a medical device for implantation into a blood vessel of an animal.\n\nAny discussion of document, devices, acts or knowledge in this specification is included to explain the context of the invention. It should not be taken as an admission that any of the material forms a part of the prior art base or the common general knowledge in the relevant art in Australia or elsewhere on or before the priority date of the disclosure and broad consistory statements herein.\n\nIn the United States alone, nearly two million people suffer from various neuromuscular disorders where control of limbs is severely impaired. In many of these patients, however, the portion of the brain responsible for movement remains intact, and it is disease and trauma to the spinal cord, nerves and muscles that limit mobility, function and independence. For these people, the ability to restore lost control at even a rudimentary level could lead to a greatly improved quality of life.",
  "cpc": [
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    "A61B 5/296",
    "A61F 2/06",
    "A61B 5/00",
    "A61F 2/90"
  ],
  "inventors": [
    "Nicholas Lachlan OPIE",
    "Thomas James Oxley",
    "Gil Simon RIND",
    "Stephen Michael RONAYNE",
    "Sam Emmanuel JOHN"
  ],
  "filing_date": "2018-04-17",
  "publication_date": "2020-08-04",
  "grant_date": "2020-08-04",
  "priority_date": "2015-10-20",
  "application_number": "US-201815955412-A",
  "family_id": "63852170",
  "cited_by_count": 28,
  "citations": [
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    "WO2017070252A1",
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  ]
}

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