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Patent · US2015366933A1 · A1 · US

Treatment of klebsiella pneumoniae with liposomally formulated glutathione

(11) Publication number
US2015366933A1
(21) Application number
14/767,985
(22) Filing date
2014-02-14
(30) Priority date
2013-02-15
(43) Publication date
2015-12-24
(52) CPC
  • A61K Preparations for medical, dental or toiletry purposes: 38/063, 9/0014, 9/0019, 9/0053, 9/006, 9/0095, 9/127, 9/4858
  • A61P Specific therapeutic activity of chemical compounds or medicinal preparations: 31/04
(73) Assignee
UNIV EMORY; YOUR ENERGY SYSTEMS LLC; CHILDRENS HEALTHCARE ATLANTA INC
(54) Title
Treatment of klebsiella pneumoniae with liposomally formulated glutathione
(57) Abstract

The composition of the invention, liposomal glutathione, has been recently shown to have utility for having an antibiotic like effect on Klebsiella pneumonia cultures in vitro, and in vivo as demonstrated by efficacy in reducing by large multiples the presence of cultures of Klebsiella in rats in animal tests. Further, because the liposomal glutathione bolsters body defenses as well as appearing to have direct killing action, the propensity to create more and more resistant strains to antibiotic treatment is downgraded.

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Claims (1)

  1. A pharmaceutical composition comprising liposomally formulated reduced glutathione for use in the treatment of a mammalian patient suffering from pneumonia, particularly caused by an infection of Klebsiella pneumoniae. 2. The pharmaceutical composition of claim 1 wherein the reduced glutathione is included inside the liposome in an amount of at least 3.3% w/w. 3. A method of treatment of a mammalian patient having Klebsiella Pneumoniae comprising: administering liposomally formulated glutathione wherein the reduced glutathione included inside the liposome is in an amount of at least 3.3% w/w.

Citations (2)

  • US2006099244A1
  • US2010069309A1
Record as JSON
{
  "publication_number": "US2015366933A1",
  "country": "US",
  "kind": "A1",
  "title": "Treatment of klebsiella pneumoniae with liposomally formulated glutathione",
  "abstract": "The composition of the invention, liposomal glutathione, has been recently shown to have utility for having an antibiotic like effect on Klebsiella pneumonia cultures in vitro, and in vivo as demonstrated by efficacy in reducing by large multiples the presence of cultures of Klebsiella in rats in animal tests. Further, because the liposomal glutathione bolsters body defenses as well as appearing to have direct killing action, the propensity to create more and more resistant strains to antibiotic treatment is downgraded.",
  "claims": [
    "1. A pharmaceutical composition comprising liposomally formulated reduced glutathione for use in the treatment of a mammalian patient suffering from pneumonia, particularly caused by an infection of Klebsiella pneumoniae. 2. The pharmaceutical composition of claim 1 wherein the reduced glutathione is included inside the liposome in an amount of at least 3.3% w/w. 3. A method of treatment of a mammalian patient having Klebsiella Pneumoniae comprising: administering liposomally formulated glutathione wherein the reduced glutathione included inside the liposome is in an amount of at least 3.3% w/w."
  ],
  "cpc": [
    "A61K 38/063",
    "A61K 9/0014",
    "A61K 9/0019",
    "A61K 9/0053",
    "A61K 9/006",
    "A61K 9/0095",
    "A61K 9/127",
    "A61K 9/4858",
    "A61P 31/04"
  ],
  "assignees": [
    "UNIV EMORY",
    "YOUR ENERGY SYSTEMS LLC",
    "CHILDRENS HEALTHCARE ATLANTA INC"
  ],
  "filing_date": "2014-02-14",
  "publication_date": "2015-12-24",
  "priority_date": "2013-02-15",
  "application_number": "US-201414767985-A",
  "family_id": "51351345",
  "citations": [
    "US2006099244A1",
    "US2010069309A1"
  ]
}

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