lymphocyte function-associated antigen-1

{
  "id": "MLC-T-AGR-003868",
  "term": "lymphocyte function-associated antigen-1",
  "field": "Agriculture and food",
  "definition": "An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A antigen comprises the alpha chain and the CD18 antigen (antigen, CD18) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-cells; B-cells; and granulocytes. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.",
  "abbreviation": "LFA-1",
  "synonyms": [
    "integrin alphaLbeta2",
    "leukocyte function associated antigen-1"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "CD antigens",
    "integrins"
  ],
  "references": [
    "Medical Subject Headings 2014",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "antígeno-1 asociado a la función del linfocito"
  },
  "url": "https://mlchart.com/terminology/agriculture/lymphocyte-function-associated-antigen-1/"
}