baclofen

{
  "id": "MLC-T-ONC-000898",
  "term": "baclofen",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug that is used to treat certain types of muscle spasms and is being studied in the treatment of liver cancer. Baclofen relaxes muscles by blocking certain nerve receptors in the spinal cord. It is a type of antispasmodic. Also called Kemstro and Lioresal.",
    "A synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis. Muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors. It acts at spinal and supraspinal sites, reducing excitatory transmission."
  ],
  "synonyms": [
    "Kemstro",
    "Lioresal"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/baclofen/"
}