Bavituximab

{
  "id": "MLC-T-ONC-000933",
  "term": "Bavituximab",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance being studied in the treatment of several types of cancer and infections caused by certain viruses. It binds to substances on the surface of tumor cells, certain viruses, and cells infected with a virus. The immune system detects bavituximab on the cells and the viruses and may destroy them. It is a type of monoclonal antibody and a type of targeted therapy agent. Also called Tarvacin.",
    "A chimeric, IgG1 monoclonal antibody directed against anionic phospholipids with potential antineoplastic activity. Bavituximab binds to anionic phospholipids in a beta 2-glycoprotein I-dependent manner, inhibiting tumor growth by stimulating antibody-dependent cellular cytotoxicity (ADCC) to tumor vessels."
  ],
  "synonyms": [
    "Tarvacin",
    "chimeric anti-phosphotidylserine monoclonal antibody"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/bavituximab/"
}