BCR-ABL1 fusion gene

{
  "id": "MLC-T-ONC-000957",
  "term": "BCR-ABL1 fusion gene",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A gene formed when pieces of chromosomes 9 and 22 break off and trade places. The ABL1 gene from chromosome 9 joins to the BCR gene on chromosome 22 to form the BCR-ABL1 fusion gene. The changed chromosome 22 with the fusion gene on it is called the Philadelphia chromosome. The BCR-ABL1 fusion gene is found in most people with chronic myelogenous leukemia, and in some people with acute lymphoblastic leukemia or acute myelogenous leukemia. Also called BCR::ABL1 fusion gene.",
    "A gene formed when pieces of chromosomes 9 and 22 break off and trade places. The ABL1 gene from chromosome 9 joins to the BCR gene on chromosome 22 to form the BCR::ABL1 fusion gene. The changed chromosome 22 with the fusion gene on it is called the Philadelphia chromosome. The BCR::ABL1 fusion gene is found in most people with chronic myelogenous leukemia, and in some people with acute lymphoblastic leukemia or acute myelogenous leukemia. Also called BCR-ABL1 fusion gene."
  ],
  "synonyms": [
    "BCR::ABL1 fusion gene",
    "BCR-ABL1 fusion gene"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/bcr-abl1-fusion-gene/"
}