BCR signaling pathway inhibitor DZD8586
Term · Oncology and biomedicine · MLC-T-ONC-011917
An inhibitor of the B-cell antigen receptor (BCR) signaling pathway, with potential antineoplastic activity. Upon administration, BCR signaling pathway inhibitor DZD8586 blocks signaling through the BCR signaling pathway. This prevents the proliferation of malignant B cells in which the BCR signaling pathway is overactivated. DZD8586 is able to cross the blood-brain barrier (BBB) and thus potentially useful in the treatment of central nervous system (CNS) metastases.
| Identifier | MLC-T-ONC-011917 |
|---|---|
| Field | Oncology and biomedicine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-011917",
"term": "BCR signaling pathway inhibitor DZD8586",
"field": "Oncology and biomedicine",
"definition": "An inhibitor of the B-cell antigen receptor (BCR) signaling pathway, with potential antineoplastic activity. Upon administration, BCR signaling pathway inhibitor DZD8586 blocks signaling through the BCR signaling pathway. This prevents the proliferation of malignant B cells in which the BCR signaling pathway is overactivated. DZD8586 is able to cross the blood-brain barrier (BBB) and thus potentially useful in the treatment of central nervous system (CNS) metastases.",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/bcr-signaling-pathway-inhibitor-dzd8586/"
}
Record 3,364 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.