MLchartDataset catalogue

BCR signaling pathway inhibitor DZD8586

Term · Oncology and biomedicine · MLC-T-ONC-011917

An inhibitor of the B-cell antigen receptor (BCR) signaling pathway, with potential antineoplastic activity. Upon administration, BCR signaling pathway inhibitor DZD8586 blocks signaling through the BCR signaling pathway. This prevents the proliferation of malignant B cells in which the BCR signaling pathway is overactivated. DZD8586 is able to cross the blood-brain barrier (BBB) and thus potentially useful in the treatment of central nervous system (CNS) metastases.

Table 1. Record
IdentifierMLC-T-ONC-011917
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-011917",
  "term": "BCR signaling pathway inhibitor DZD8586",
  "field": "Oncology and biomedicine",
  "definition": "An inhibitor of the B-cell antigen receptor (BCR) signaling pathway, with potential antineoplastic activity. Upon administration, BCR signaling pathway inhibitor DZD8586 blocks signaling through the BCR signaling pathway. This prevents the proliferation of malignant B cells in which the BCR signaling pathway is overactivated. DZD8586 is able to cross the blood-brain barrier (BBB) and thus potentially useful in the treatment of central nervous system (CNS) metastases.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/bcr-signaling-pathway-inhibitor-dzd8586/"
}

Record 3,364 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.