Birt-Hogg-Dubé syndrome

{
  "id": "MLC-T-ONC-001084",
  "term": "Birt-Hogg-Dubé syndrome",
  "field": "Oncology and biomedicine",
  "definition": "A rare, inherited disorder in which benign (not cancer) skin lesions called fibrofolliculomas form in the hair follicles on the face, neck, and chest. Patients with Birt-Hogg-Dubé syndrome have an increased risk of kidney cancer and benign kidney tumors. They may also have lung cysts and a condition called a pneumothorax, in which all or part of the lung collapses. The signs and symptoms of Birt-Hogg-Dubé syndrome usually do not appear until young adulthood. It is caused by a mutation (change) in a gene called FLCN.",
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/birt-hogg-dube-syndrome/"
}