bismuth Bi213 monoclonal antibody M195

{
  "id": "MLC-T-ONC-012029",
  "term": "bismuth Bi213 monoclonal antibody M195",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate consisting of murine monoclonal antibody (M195) and bismuth 213 (Bi213). Monoclonal antibody M195 binds to CD33, a surface antigen expressed by myelogenous leukemia cells. Bismuth 213 is an isotope that emits short-ranged high-energy alpha particles. This radioimmunoconjugate selectively delivers alpha particle-mediated cytotoxicity to leukemic cells, thereby limiting the exposure of normal tissues to ionizing radiation.",
  "abbreviation": "Bi213 MOAB M195",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/bismuth-bi213-monoclonal-antibody-m195/"
}