MLchartDataset catalogue

EGFR/HER2 inhibitor TAS2940

Term · Oncology and biomedicine · MLC-T-ONC-013277

An orally bioavailable, small molecule inhibitor of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with potential antineoplastic activity. Upon oral administration, EGFR/HER2 inhibitor TAS2940 targets, binds to and inhibits EGFR and HER2, which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization.

Table 1. Record
IdentifierMLC-T-ONC-013277
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013277",
  "term": "EGFR/HER2 inhibitor TAS2940",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable, small molecule inhibitor of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with potential antineoplastic activity. Upon oral administration, EGFR/HER2 inhibitor TAS2940 targets, binds to and inhibits EGFR and HER2, which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/egfr-her2-inhibitor-tas2940/"
}

Record 6,470 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.