MLchartDataset catalogue

evocalcet

Term · Oncology and biomedicine · MLC-T-ONC-013476

An orally available calcium receptor (CaR) modulator, with potential calcimimetic activity. Upon administration, evocalcet allosterically binds to and inhibits the activity of CaR, thereby suppressing the production of serum parathyroid hormone (PTH) and prevents the PTH-mediated efflux of calcium from bone and normalizes calcium levels.

Table 1. Record
IdentifierMLC-T-ONC-013476
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013476",
  "term": "evocalcet",
  "field": "Oncology and biomedicine",
  "definition": "An orally available calcium receptor (CaR) modulator, with potential calcimimetic activity. Upon administration, evocalcet allosterically binds to and inhibits the activity of CaR, thereby suppressing the production of serum parathyroid hormone (PTH) and prevents the PTH-mediated efflux of calcium from bone and normalizes calcium levels.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/evocalcet/"
}

Record 7,006 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.