fentanyl citrate

{
  "id": "MLC-T-ONC-003164",
  "term": "fentanyl citrate",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to treat severe pain in people with chronic conditions, such as cancer, who have not gotten better after treatment with other opioids. It is also used to treat pain after surgery. Fentanyl citrate works by binding to mu opioid receptors in the central nervous system, which blocks pain signals and alters how the body responds to pain. It is a type of synthetic opioid agonist that acts as an analgesic (pain reliever). Also called Actiq.",
    "The citrate salt of fentanyl, a synthetic opioid related to the phenylpiperidines with analgesic and anesthetic properties. Fentanyl exerts its analgesic effect by selectively binding to the mu-opioid receptor in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. Additional pharmacological effects of fentanyl include anxiolysis, euphoria, feelings of relaxation, respiratory depression, constipation, miosis, and cough suppression."
  ],
  "synonyms": [
    "Actiq"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fentanyl-citrate/"
}