Fosfomycin tromethamine

{
  "id": "MLC-T-ONC-013762",
  "term": "Fosfomycin tromethamine",
  "field": "Oncology and biomedicine",
  "definition": "The tromethamine salt form of fosfomycin, a synthetic broad-spectrum antibiotic. Fosfomycin tromethamine binds to and inactivates the enzyme enolpyruvyl transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis. In addition, fosfomycin tromethamine reduces the adherence of bacteria to uroepithelial cells.",
  "synonyms": [
    "fosfomycin trometamol salt",
    "fosfomycin compound with trometamol"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fosfomycin-tromethamine/"
}