KRAS mutant inhibitor KQB365

{
  "id": "MLC-T-ONC-014675",
  "term": "KRAS mutant inhibitor KQB365",
  "field": "Oncology and biomedicine",
  "definition": "An inhibitor of one or more KRAS mutations, with potential antineoplastic activity. Upon administration, KRAS mutant inhibitor KQB365 targets, binds to and inhibits one or more KRAS mutations, thereby inhibiting KRAS mutant-dependent signaling. This inhibits the proliferation of and induces apoptosis in tumor cells in which KRAS is mutated. KRAS plays an important role in cell signaling, division and differentiation. Mutations of KRAS may induce constitutive signal transduction leading to tumor cell growth, proliferation, invasion, and metastasis.",
  "synonyms": [
    "KRAS inhibitor KQB365"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/kras-mutant-inhibitor-kqb365/"
}