Talc

{
  "id": "MLC-T-ONC-008505",
  "term": "Talc",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A mist or powdered form of the mineral magnesium silicate that is used to prevent malignant pleural effusions from coming back. Malignant pleural effusion is a condition in which cancer causes an abnormal collection of fluid in the space between the lung and chest wall. When talc is given through a tube inserted into the pleural space, it causes the space to close up so fluid cannot collect there. Talc is a type of sclerosing agent. Also called Sclerosol Intrapleural Aerosol, Sterile Talc Powder, and Steritalc.",
    "Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity."
  ],
  "synonyms": [
    "Sclerosol Intrapleural Aerosol",
    "Sterile Talc Powder",
    "Steritalc"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/talc/"
}