Tecogalan sodium

{
  "id": "MLC-T-ONC-017039",
  "term": "Tecogalan sodium",
  "field": "Oncology and biomedicine",
  "definition": "A sulfated polysaccharide isolated from various Arthrobacter bacterial species. Possessing potential antiangiogenic and antineoplastic properties, tecogalan binds to basic fibroblast growth factor (bFGF), thereby preventing bFGF from binding to its receptors. Disruption of this receptor binding results in the inhibition of bFGF-stimulated endothelial cell growth, proliferation, and migration.",
  "abbreviation": "SP-PG",
  "synonyms": [
    "Sulfated Polysaccharide Tecogalan DS-4152"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tecogalan-sodium/"
}