Tributyrin
Term · Oncology and biomedicine · MLC-T-ONC-008897
A triglyceride drug that may inhibit cell growth and induce cell differentiation. Differentiating agents may be effective in changing cancer cells back into normal cells.
A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate, the active metabolite of tributyrin, inhibits histone deacetylase, resulting in increased differentiation, decreased proliferation, cell cycle arrest, and apoptosis in some tumor cell lines.
| Identifier | MLC-T-ONC-008897 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | TB |
| Synonyms | butyryl triglyceride; glyceryl tributyrate |
| References | NCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-008897",
"term": "Tributyrin",
"field": "Oncology and biomedicine",
"definitions": [
"A triglyceride drug that may inhibit cell growth and induce cell differentiation. Differentiating agents may be effective in changing cancer cells back into normal cells.",
"A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate, the active metabolite of tributyrin, inhibits histone deacetylase, resulting in increased differentiation, decreased proliferation, cell cycle arrest, and apoptosis in some tumor cell lines."
],
"abbreviation": "TB",
"synonyms": [
"butyryl triglyceride",
"glyceryl tributyrate"
],
"references": [
"NCI Dictionary of Cancer Terms",
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/tributyrin/"
}
Record 16,700 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.