yeast-derived beta-glucan supplement

{
  "id": "MLC-T-ONC-017613",
  "term": "yeast-derived beta-glucan supplement",
  "field": "Oncology and biomedicine",
  "definition": "A dietary supplement composed of yeast-derived beta-glucan, with potential antioxidant, anti-inflammatory and immunomodulatory activities. Upon administration of yeast-derived beta-glucan supplement, beta-glucan may decrease both superoxide dismutase and reductase activities and the release of pro-inflammatory cytokines, thereby reducing oxidative stress and inflammation. Beta-glucan may also stimulate the immune system by binding to a lectin site within the complement receptor 3 (CR3 or iC3b receptor) on leukocytes, priming the receptor to trigger cytotoxic degranulation of leukocytes when leukocyte CR3 binds to iC3b-opsonized cells. iC3b is the proteolyticly inactive product of the complement cleavage fragment C3b.",
  "synonyms": [
    "yeast-derived beta-glucan"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/yeast-derived-beta-glucan-supplement/"
}