ziconotide

{
  "id": "MLC-T-ONC-009477",
  "term": "ziconotide",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used in the treatment of chronic pain. Also called Prialt and SNX 111.",
    "A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with analgesic activity. Ziconotide appears to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission from pain-sensing primary nociceptors. This agent may exhibit significant analgesic activity in refractory pain."
  ],
  "synonyms": [
    "Prialt",
    "SNX 111"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ziconotide/"
}