zirconium Zr 89-DFO-starPEG

{
  "id": "MLC-T-ONC-017691",
  "term": "zirconium Zr 89-DFO-starPEG",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate containing starPEG, a 4-armed polyethylene glycol (PEG)-based nanodrug carrier moiety, linked, via the chelator desferrioxamine (DFO), to the radioisotope zirconium Zr 89 (Zr89), with potential use as an imaging agent upon positron emission tomography (PET) imaging. Upon administration, starPEG is taken up by tumors due to enhanced permeability and retention (EPR) effect. Upon PET imaging, EPR-mediated tumor uptake and distribution of the nanodrug carrier may be visualized.",
  "synonyms": [
    "(89Zr)DFO-starPEG",
    "89-Zr-DFO-star polyethylene glycol",
    "89Zr-labeled DFO-starPEG",
    "Zr89-DFO-starPEG"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/zirconium-zr-89-dfo-starpeg/"
}