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Patent · US11204361B2 · B2 · US

Laboratory automation system

(11) Publication number
US11204361B2
(21) Application number
15/875,215
(22) Filing date
2018-01-19
(30) Priority date
2017-02-03
(43) Publication date
2021-12-21
(45) Date of grant
2021-12-21
(51) IPC
B65G 54/02; G01N 21/51; G01N 35/00; G01N 35/04; G01N 35/10; G06T 7/00; G06T 7/60
(52) CPC
  • G01N Investigating or analysing materials by determining their chemical or physical properties: 35/10, 2035/00801, 2035/00821, 2035/00851, 2035/0401, 2035/0406, 2035/0477, 2035/0493, 21/51, 35/00732, 35/04
  • B01L Chemical or physical laboratory apparatus for general use: 2200/18, 2300/023, 3/5082, 9/06
  • B65G Transport or storage devices, e.g. conveyors for loading or tipping, shop conveyor systems or pneumatic tube conveyors: 54/02
  • G06T Image data processing or generation, in general: 7/0012, 7/60
(73) Assignee
ROCHE DIAGNOSTICS OPERATIONS INC
(72) Inventors
BIRRER ARMIN; DRECHSLER ANDREAS; HARBERS RIK
(54) Title
Laboratory automation system
(57) Abstract

A laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system comprises a digital camera configured to take an image of the sample container together with a calibration element. The image comprises image data related to the sample container and image data related to the calibration element. The laboratory automation system also comprises an image processing device configured to determine geometrical properties of the sample container depending on the image data related to the sample container and the image data related to the calibration element.

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Claims (4)

  1. A laboratory automation system for processing sample containers containing laboratory samples, the laboratory automation system comprising: a sample container; a calibration element, wherein the calibration element is attached to the sample container, wherein the sample container is closed by a cap and wherein the cap serves as the calibration element; a digital camera configured to take an image of the sample container together with the calibration element, wherein the image comprises image data related to the sample container and image data related to the calibration element; an image processing device configured to determine pixel data of the sample container and the calibration element from the image data received from the digital camera by pattern recognition, wherein the image processing device is configured to count the number of pixels along a coordinate for the sample container and for the cap and determine geometrical properties of the sample container in along the same coordinate based on a rule of three, using the counted pixels along the same coordinate and known geometric properties of the cap; and a transport plane, a driver configured to move the sample container carriers on top of the transport plane, and a control device configured to control the movement of the sample container carriers on top of the transport plane by driving the driver such that the sample container carriers move along corresponding transport paths, wherein the driver is electro-magnetic actuators located below the transport plane and controllable by the control device, and the sample container carriers respectively comprise a magnetically active device for interaction with a magnetic field generated by the electro-magnetic actuators such that a magnetic drive force is applied to the sample container carriers.
  2. The laboratory automation system according to claim 1, wherein the digital camera is a digital color camera, wherein the calibration element has defined color properties, wherein the image processing device is configured to calibrate the digital color camera depending on the defined color properties of the calibration element.
  3. The laboratory automation system according to claim 1, further comprises, a pipetting station, wherein the pipetting station is configured to operate in response to the determined geometrical properties of the sample container.
  4. The laboratory automation system according to claim 1, further comprises, a plurality of laboratory stations configured to process the samples comprised in the sample containers.

Description

The present disclosure generally relates to a laboratory automation system. A known laboratory automation system comprises an image processing device adapted to determine geometrical properties of a sample container depending on image data related to the sample container. However, such image processing devices typically require a geometry and color calibration to ensure proper functioning. A typical laboratory sample distribution system being used in a laboratory automation system comprises a number of sample container carriers adapted to carry one or more sample containers, a transport plane adapted to support the sample container carriers, a number of electro-magnetic actuators adapted to move the sample container carriers on top of the transport plane by applying a magnetic force to the sample container carriers, and a control device adapted to control the movement of the sample container carriers on top of the transport plane by driving the electro-magnetic actuators. However, there is a need for a laboratory automation system having a reliable and cost effective geometry and/or color calibration.

According to the present disclosure, a laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system can comprise a digital camera configured to take an image of the sample container together with a calibration element. The image can comprise image data related to the sample container and image data related to the calibration element.

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Record as JSON
{
  "publication_number": "US11204361B2",
  "country": "US",
  "kind": "B2",
  "title": "Laboratory automation system",
  "abstract": "A laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system comprises a digital camera configured to take an image of the sample container together with a calibration element. The image comprises image data related to the sample container and image data related to the calibration element. The laboratory automation system also comprises an image processing device configured to determine geometrical properties of the sample container depending on the image data related to the sample container and the image data related to the calibration element.",
  "claims": [
    "1. A laboratory automation system for processing sample containers containing laboratory samples, the laboratory automation system comprising: a sample container; a calibration element, wherein the calibration element is attached to the sample container, wherein the sample container is closed by a cap and wherein the cap serves as the calibration element; a digital camera configured to take an image of the sample container together with the calibration element, wherein the image comprises image data related to the sample container and image data related to the calibration element; an image processing device configured to determine pixel data of the sample container and the calibration element from the image data received from the digital camera by pattern recognition, wherein the image processing device is configured to count the number of pixels along a coordinate for the sample container and for the cap and determine geometrical properties of the sample container in along the same coordinate based on a rule of three, using the counted pixels along the same coordinate and known geometric properties of the cap; and a transport plane, a driver configured to move the sample container carriers on top of the transport plane, and a control device configured to control the movement of the sample container carriers on top of the transport plane by driving the driver such that the sample container carriers move along corresponding transport paths, wherein the driver is electro-magnetic actuators located below the transport plane and controllable by the control device, and the sample container carriers respectively comprise a magnetically active device for interaction with a magnetic field generated by the electro-magnetic actuators such that a magnetic drive force is applied to the sample container carriers.",
    "2. The laboratory automation system according to claim 1, wherein the digital camera is a digital color camera, wherein the calibration element has defined color properties, wherein the image processing device is configured to calibrate the digital color camera depending on the defined color properties of the calibration element.",
    "3. The laboratory automation system according to claim 1, further comprises, a pipetting station, wherein the pipetting station is configured to operate in response to the determined geometrical properties of the sample container.",
    "4. The laboratory automation system according to claim 1, further comprises, a plurality of laboratory stations configured to process the samples comprised in the sample containers."
  ],
  "description_excerpt": "The present disclosure generally relates to a laboratory automation system. A known laboratory automation system comprises an image processing device adapted to determine geometrical properties of a sample container depending on image data related to the sample container. However, such image processing devices typically require a geometry and color calibration to ensure proper functioning. A typical laboratory sample distribution system being used in a laboratory automation system comprises a number of sample container carriers adapted to carry one or more sample containers, a transport plane adapted to support the sample container carriers, a number of electro-magnetic actuators adapted to move the sample container carriers on top of the transport plane by applying a magnetic force to the sample container carriers, and a control device adapted to control the movement of the sample container carriers on top of the transport plane by driving the electro-magnetic actuators. However, there is a need for a laboratory automation system having a reliable and cost effective geometry and/or color calibration.\n\nAccording to the present disclosure, a laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system can comprise a digital camera configured to take an image of the sample container together with a calibration element. The image can comprise image data related to the sample container and image data related to the calibration element.",
  "cpc": [
    "G01N 35/10",
    "B01L 2200/18",
    "B01L 2300/023",
    "B01L 3/5082",
    "B01L 9/06",
    "B65G 54/02",
    "G01N 2035/00801",
    "G01N 2035/00821",
    "G01N 2035/00851",
    "G01N 2035/0401",
    "G01N 2035/0406",
    "G01N 2035/0477",
    "G01N 2035/0493",
    "G01N 21/51",
    "G01N 35/00732",
    "G01N 35/04",
    "G06T 7/0012",
    "G06T 7/60"
  ],
  "ipc": [
    "B65G 54/02",
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    "G01N 35/00",
    "G01N 35/04",
    "G01N 35/10",
    "G06T 7/00",
    "G06T 7/60"
  ],
  "assignees": [
    "ROCHE DIAGNOSTICS OPERATIONS INC"
  ],
  "inventors": [
    "BIRRER ARMIN",
    "DRECHSLER ANDREAS",
    "HARBERS RIK"
  ],
  "filing_date": "2018-01-19",
  "publication_date": "2021-12-21",
  "grant_date": "2021-12-21",
  "priority_date": "2017-02-03",
  "application_number": "US-201815875215-A",
  "family_id": "57965786",
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Record 554 of 5,000 in Patents full text (MLC-0201). Request the full dataset.