Integrated system for the infixion and retrieval of implants

{
  "publication_number": "US11389171B2",
  "country": "US",
  "kind": "B2",
  "title": "Integrated system for the infixion and retrieval of implants",
  "abstract": "Described are coordinated apparatus and methods for drug targeting, clearing the lumen, placing implants within the wall of, and stenting, as necessary, any tubular anatomical structure with single luminal entry. Miniature balls, or miniballs, are introduced into the wall aeroballistically from within the lumen, or small arcuate bands called stays inserted through the outer tunic by means of a hand tool. When miniballs must be placed too closely together to be controlled by hand, a positional control system assists in discharge. Implantation within or proximal to diseased tissue targeting, and thus concentrating the medication in that tissue, miniballs and stays can be used to deliver and controllably release multiple drugs, a radionuclide, or an open or closed loop smart-pill, for example. A glossary of terms follows the specification. Balance of abstract appended to the section entitled Summary of the Invention.",
  "claims": [
    "1. A jacket for encircling a tubular anatomical structure, wherein said jacket comprises i) complementary open-ended semi cylindrical shells fastened together along one long edge by spring-loaded hinges to urge said semi cylindrical shells into a cylindrical conformation when closed, ii) one or more outrigger stabilizers, and iii) a bridge connecting said stabilizer to one of the semi cylindrical shells, said bridge comprising aligned semicircular arms; wherein said jacket is lined with a shape-compliant material and incorporating material magnetized perpendicularly to the long axis of said tubular anatomical structure to draw magnetically susceptible matter within said structure abaxially outward toward said jacket.",
    "2. A jacket according to claim 1 wherein said jacket derives its magnetism by incorporation from the group of magnetic materials comprising an intrinsically magnetic metal, an intrinsically magnetic polymer, small permanent magnets fastened about the outer surface of said jacket, and these in combinations to draw magnetically susceptible matter from a ferrofluid coursing through said lumen of said tubular anatomical structure and hold said matter up against the lumen lining of said structure.",
    "3. A jacket according to claim 1 wherein said jacket uses magnetism obtained by selection from the group comprising an intrinsically magnetic metal, and intrinsically magnetic polymer, and small permanent magnets fastened about the outer surface of said jacket to exercise a stenting function by drawing small magnetically susceptible bodies infixed within the wall of said tubular anatomical structure radially outward.",
    "4. A jacket according to claim 1 wherein the magnetized material of said jacket draws magnetically susceptible matter from a ferrofluid coursing through said lumen and hold said matter up against the lumen lining of said structure.",
    "5. A jacket according to claim 1 wherein said jacket uses magnetism provided by electromagnets fastened about the outer surface of said jacket to draw magnetically susceptible matter from a ferrofluid coursing through said lumen and draw said matter into the lumen wall of said structure.",
    "6. A jacket according to claim 5 wherein said electromagnets are adjusted in field strength in response to a prescription program executed by a microprocessor."
  ],
  "description_excerpt": "TABLE OF CONTENTS\n\nCROSS REFERENCE TO RELATED APPLICATION\n\nTABLE OF CONTENTS\n\nBACKGROUND OF THE INVENTION\n\n1. Field of the invention\n\n2. Preliminary description of the invention\n\n3.Terminology\n\n4. Concept of the ductus-intramural implant\n\n4a. Tissue acceptance of ductus-intramural implant\n\n4a(1). Significance of sterile antixenic immune tissue reaction\n\n4a(2). Duration, extent, and outcome of sterile tissue reaction\n\n4a(3). Tissue reaction ameliorative measures\n\n4b. Medicinal and medicated miniballs and stays\n\n4b(1). Drug-releasing and irradiating miniballs, stays, and ferrofluids\n\n4b(2). Local release of miniballs and stays\n\n4b(3). Use of drug-releasing ductus-intramural implants to locally counteract or reinforce angiogenic or other systemic medication\n\n4b(4). System implant magnetic drug and radiation targeting\n\n4b(5). Circulating drug-blocking and drug interaction avoidance\n\n4b(6). Drug-targeting miniballs and stays\n\n4c. Implants that radiate heat on demand\n\n4d. Chemical adjuvants and precautionary measures\n\n4d(1). Administration of target and target-adjacent implantation-preparatory substances\n\n4d(2). Ductus wall tumefacients\n\n4d(3). Nontumefacient enables attainment of implantable ductus-intramural thickness\n\n4e. Stabilization of the implant insertion site\n\n4e(1). Gross positional stabilization (immobilization) of the implant insertion site\n\n4e(2). Tissue stabilization at the treatment site\n\n4e(2)(a). Temperature stabilization\n\n4e(2)(b). Removal of vulnerable plaque or accreted material at the implant insertion site",
  "cpc": [
    "A61B 17/12118",
    "A61B 17/00491",
    "A61B 17/0057",
    "A61B 17/12181",
    "A61B 17/3468",
    "A61B 18/18",
    "A61B 2017/00411",
    "A61B 2017/0065",
    "A61B 2017/00876",
    "A61B 2017/1205",
    "A61F 2/82"
  ],
  "ipc": [
    "A61B 17/00",
    "A61B 17/12",
    "A61B 17/34",
    "A61B 18/18",
    "A61F 2/82"
  ],
  "inventors": [
    "David S. Goldsmith"
  ],
  "filing_date": "2018-02-14",
  "publication_date": "2022-07-19",
  "grant_date": "2022-07-19",
  "priority_date": "2006-11-21",
  "application_number": "US-201815932172-A",
  "family_id": "67540634",
  "cited_by_count": 21,
  "citations": [
    "US6030334A",
    "US20020151760A1",
    "US20060129228A1",
    "US20050143801A1",
    "US20050149002A1",
    "US20060041182A1",
    "US20080101677A1",
    "US20140163664A1",
    "US20120277774A1"
  ]
}