Lifting basket, lifting basket guiding mechanism and lifting basket-type sample cryogenic storage device

{
  "publication_number": "US12275602B1",
  "country": "US",
  "kind": "B1",
  "title": "Lifting basket, lifting basket guiding mechanism and lifting basket-type sample cryogenic storage device",
  "abstract": "A lifting basket, a lifting basket guiding mechanism and a lifting basket-type sample cryogenic storage device are provided. The guiding mechanism includes a storage member, an auxiliary guiding member and a driving member. The storage member is placed into a liquid nitrogen tank, provided with an opening at an upper end and sleeved onto an exterior of the lifting basket for restricting removal of a cryogenic vial storage member or a cryogenic vial stored inside the lifting basket. The auxiliary guiding member is arranged above the storage member and slidably connected to the storage member, and the auxiliary guiding member is sleeved onto the exterior of the lifting basket and is in contact with the lifting basket to perform relative sliding motion through a guiding structure. The auxiliary guiding member performs vertical motion relative to a storage frame and the lifting basket under the control of the driving member.",
  "claims": [
    "1. A lifting basket guiding mechanism, comprising a storage member being placed into a liquid nitrogen tank as a whole, wherein the storage member is provided with an opening at an upper end and sleeved onto an exterior of a lifting basket and is configured to restrict a removal of a cryogenic vial storage member or a cryogenic vial stored inside the lifting basket from a side; further comprising an auxiliary guiding member, wherein the auxiliary guiding member is arranged above the storage member and is slidably connected to the storage member, and the auxiliary guiding member is sleeved onto the exterior of the lifting basket and is in contact with the lifting basket to perform relative sliding motion through a guiding structure; and further comprising a driving member, wherein the auxiliary guiding member performs vertical motion relative to a storage frame and the lifting basket under a control of the driving member.",
    "2. The lifting basket guiding mechanism according to claim 1, wherein the storage member comprises the storage frame, wherein the storage frame forms a shield around sides of the lifting basket capable of restricting sideways sliding of the cryogenic vial storage member or the cryogenic vial stored in the lifting basket; and the storage frame is provided with cooling ports.",
    "3. The lifting basket guiding mechanism according to claim 2, wherein an outer side of the storage frame is further provided with a connecting member, such that the storage frame can be installed inside the liquid nitrogen tank or on a rotating mechanism inside the liquid nitrogen tank.",
    "4. The lifting basket guiding mechanism according to claim 3, wherein the auxiliary guiding member comprises an auxiliary guiding frame, one end of the auxiliary guiding frame is slidably connected to the storage frame via a slide rail and slot pair, and the other end thereof is fixedly connected to the driving member.",
    "5. The lifting basket guiding mechanism according to claim 4, wherein the driving member comprises a driving motor, an output end of the driving motor is connected to the auxiliary guiding frame via a sliding block, and the sliding block is arranged on a fixed rail.",
    "6. The lifting basket guiding mechanism according to claim 4, wherein the guiding structure comprises guiding wheels that are arranged on an inner side of the auxiliary guiding frame, and can be in contact with the lifting basket for sliding.",
    "7. A lifting basket, comprising a lifting basket body for storing the cryogenic vial storage member or the cryogenic vial; and the lifting basket body is further provided with the lifting basket guiding mechanism according to claim 1.",
    "8. A lifting basket-type sample cryogenic storage device, comprising a cryogenic storage area and an operating area, wherein the cryogenic storage area is provided with a liquid nitrogen tank, and the lifting basket according to claim 7 is arranged inside the liquid nitrogen tank.",
    "9. The lifting basket-type sample cryogenic storage device according to claim 8, wherein a rotating mechanism is further arranged inside the liquid nitrogen tank, the rotating mechanism is connected to the lifting basket and is thus capable of rotating the lifting basket to a position corresponding to a storage door of the liquid nitrogen tank.",
    "10. The lifting basket-type sample cryogenic storage device according to claim 9, wherein the rotating mechanism comprises a rotating motor, a rotating shaft, a supporting turntable, and a base that are connected in sequence, wherein the rotating motor is arranged outside the liquid nitrogen tank, the base is connected inside the liquid nitrogen tank, and the lifting basket guiding mechanism is installed on the supporting turntable.",
    "11. The lifting basket-type sample cryogenic storage device according to claim 8, wherein the operating area is provided with a lifting mechanism, which is arranged above a storage door of the liquid nitrogen tank and is configured for extracting or storing the lifting basket.",
    "12. The lifting basket-type sample cryogenic storage device according to claim 11, wherein the lifting mechanism comprises a lifting motor, a slide rail, a vertical guide plate, and a lifting platform, wherein the lifting motor and the slide rail are fixedly connected to the vertical guide plate, and the lifting platform is slidably connected to the slide rail and is driven by the lifting motor to move up and down; and the lifting platform is provided with a hook portion for grabbing the lifting basket.",
    "13. The lifting basket-type sample cryogenic storage device according to claim 12, wherein the lifting mechanism further comprises a position sensor, which is arranged on the slide rail and is configured to detect an operating position of the lifting platform.",
    "14. The lifting basket-type sample cryogenic storage device according to claim 11, wherein the driving member of the lifting basket guiding mechanism is arranged on the vertical guide plate of the lifting mechanism.",
    "15. The lifting basket-type sample cryogenic storage device according to claim 8, wherein the operating area is provided with a lid removal mechanism, which comprises a lid removal motor, a lead screw nut assembly, and a lid removal plate, wherein the lid removal plate is arranged horizontally and fixed to nuts of the lead screw nut assembly, and an output end of the lid removal motor is coaxially connected to a lead screw of the lead screw nut assembly.",
    "16. The lifting basket-type sample cryogenic storage device according to claim 8, wherein the operating area is further provided with a scraper blade mechanism, which comprises a scraper blade motor, a slide slot and slide block assembly, and a scraper blade, one end of the horizontally arranged scraper blade is fixedly connected to a slide block of the slide slot and slide block assembly, and the other end thereof is an output end of the scraper blade motor.",
    "17. The lifting basket according to claim 7, wherein in the lifting basket guiding mechanism, the storage member comprises the storage frame, wherein the storage frame forms a shield around sides of the lifting basket capable of restricting sideways sliding of the cryogenic vial storage member or the cryogenic vial stored in the lifting basket; and the storage frame is provided with cooling ports.",
    "18. The lifting basket according to claim 17, wherein in the lifting basket guiding mechanism, an outer side of the storage frame is further provided with a connecting member, such that the storage frame can be installed inside the liquid nitrogen tank or on a rotating mechanism inside the liquid nitrogen tank.",
    "19. The lifting basket according to claim 18, wherein in the lifting basket guiding mechanism, the auxiliary guiding member comprises an auxiliary guiding frame, one end of the auxiliary guiding frame is slidably connected to the storage frame via a slide rail and slot pair, and the other end thereof is fixedly connected to the driving member.",
    "20. The lifting basket according to claim 19, wherein in the lifting basket guiding mechanism, the driving member comprises a driving motor, an output end of the driving motor is connected to the auxiliary guiding frame via a sliding block, and the sliding block is arranged on a fixed rail."
  ],
  "description_excerpt": "The present disclosure belongs to the technical field of biological sample storage, and relates to a lifting basket, a lifting basket guiding mechanism and a lifting basket-type sample cryogenic storage device.\n\nLong-term storage of a biological sample usually requires a lowest possible temperature to minimize biochemical reactions of the sample and improve the stability of various components of the sample. The lower the temperature, the longer the sample preservation time will be.\n\nA cryogenic preserved sample is usually placed in a cryogenic vial to protect cells therein, the cryogenic vial is then placed in liquid nitrogen via a cryogenic rack/cryogenic box or directly submerged in the liquid nitrogen, so as to achieve long-term stable preservation of the sample. More specifically, the cryogenic rack/cryogenic box or the cryogenic vial is usually placed into a liquid nitrogen tank via a lifting basket for freezing.\n\nAt present, in order to enhance stability of the lifting basket when the lifting basket is lifted, a conventional lifting basket mechanism is provided with a plurality of sections of sliding rods or other guiding structures on sidewalls of the lifting basket, such that a scraper blade assembly on a side can easily extract a rack. However, the sliding rods and other guiding structures are not resistant to the low temperature, and will deform and frost when being immersed in the liquid nitrogen for a long period of time.",
  "cpc": [
    "B65G 47/90",
    "A01N 1/142",
    "A01N 1/145",
    "B65G 2201/0235",
    "C12N 5/545",
    "F25D 25/00",
    "F25D 25/04",
    "F25D 3/105"
  ],
  "ipc": [
    "A01N 1/142",
    "B65G 47/90"
  ],
  "assignees": [
    "Shanghai OriginCell Biological Cryo Equipment Co Ltd"
  ],
  "inventors": [
    "Jianguo Qu",
    "Yunxin CAO"
  ],
  "filing_date": "2023-04-21",
  "publication_date": "2025-04-15",
  "grant_date": "2025-04-15",
  "priority_date": "2022-05-16",
  "application_number": "US-202318856079-A",
  "family_id": "83651557",
  "cited_by_count": 0,
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}