Opening apparatus for container, analysis device, closing apparatus for container, and reagent kit

{
  "publication_number": "US2023390943A1",
  "country": "US",
  "kind": "A1",
  "title": "Opening apparatus for container, analysis device, closing apparatus for container, and reagent kit",
  "abstract": "An opening apparatus includes a temperature adjustment section that holds a container body of a PCR container, an opening/closing unit, a moving device, and a control device. The opening and closing unit includes: a rotating member that applies a force to a lid in a direction to open the lid as the rotating member rotates with a projection in contact with the lid in a closed state; and a motor that rotates the rotating member. The moving device moves the temperature adjustment section relative to the rotating member. In conjunction with driving and thus rotating the rotating member, the control device controls the moving device so that the PCR container moves horizontally in a direction from a hinge of the PCR container toward a flange of the PCR container.",
  "claims": [
    "1. An opening apparatus for a container including a container body, a lid, and a hinge that interconnects the container body and the lid, comprising: a holding device that holds the container body; an opening device including a rotating member and a drive device that rotates the rotating member, the rotating member having a first projection and a second projection capable of coming into contact with the lid, the rotating member being configured to apply a force to the lid in a direction to open the lid by rotating while one of the first and second projections is in contact with the lid in a closed state; a moving device that moves at least one of the holding device and the rotating member relatively to the other; and a control device that controls the opening device and the moving device in conjunction with each other to open the lid. 2. The opening apparatus for a container according to claim 1, wherein a flange is provided at a tip of the lid, the control device controls the moving device so that a set state is set in which while the container body is held by the holding device and the lid is positioned above the container body, the first projection of the rotating member is in contact with a lower surface of the flange of the lid and the second projection of the rotating member is in contact with an upper surface of the hinge of the lid, and the control device controls the opening device in the set state so that the rotating member rotates in a direction to displace the flange upward. 3. The opening apparatus for a container according to claim 2, wherein, in conjunction with rotating the rotating member, the control device controls the moving device so that the container moves horizontally in a direction from the hinge toward the flange. 4. The opening apparatus for a container according to claim 1, wherein the rotating member has an end portion different from the first and second projections, and the end portion applies a force to the lid in a direction to close the lid when the rotating member rotates in the direction to close the lid while the rotating member is in contact with the lid in an open state. 5. The opening apparatus for a container according to claim 1, wherein at least one of the first and second projections of the rotating member applies a force to the lid in a direction to close the lid when the rotating member rotates in the direction to close the lid while the rotating member is in contact with the lid in an open state. 6. The opening apparatus for a container according to claim 1, wherein the holding device has an arrangement surface in which a plurality of containers each being the container are two-dimensionally disposed, and the moving device is configured to move at least one of the holding device and the rotating member relative to the other in a two-dimensional manner along the arrangement surface. 7. The opening apparatus for a container according to claim 1, further comprising an irradiation device that irradiates at least one of the first and second projections of the rotating member partially or entirely with ultraviolet ray. 8. The opening apparatus for a container according to claim 7, wherein the control device controls the irradiation device so that, after at least one of the first and second projections is brought into contact with the lid of the container with an analyte contained therein, the at least one of the projections brought into contact with the lid is partially or entirely irradiated with ultraviolet ray. 9. The opening apparatus for a container according to claim 1, wherein the holding device has a function to heat the container, and the control device controls the opening device and the moving device so that the lid is opened at a first angle when the lid is brought to an open state before the holding device heats the container, and the opening device and the moving device so that the lid is opened at a second angle when the lid is brought to an open state after the holding device heats the container, the second angle being larger than the first angle. 10. An analysis device comprising: an opening apparatus according to claim 1; and a dispensing device that dispenses a reagent into a container opened by the opening apparatus. 11. The analysis device according to claim 10, further comprising a pipette tip used to dispense liquid into the container, wherein the dispensing device includes a nozzle that allows the pipette tip to be detachable therefrom, and the control device controls the moving device so that when liquid is dispensed into the container via the pipette tip attached to the nozzle the pipette tip moves horizontally from a side of a tip of the lid toward the hinge. 12. The analysis device according to claim 1, wherein a polymerase chain reaction is used to analyze a gene. 13. A closing apparatus for a container including a container body, a lid, and a hinge that interconnects the container body and the lid, comprising: a holding device that holds the container body; a closing device including a rotating member and a drive device that rotates the rotating member, the rotating member being configured to apply a force to the lid in a direction to close the lid by rotating in contact with the lid in an open state; and a control device that controls the closing device, wherein when the lid in the open state is brought to a closed state, the control device performs a first closing control to apply a force to the lid in a direction to close the lid by rotating the rotating member so that a portion of the rotating member approaches the hinge while the portion of the rotating member is in contact with the lid. 14. The closing apparatus for a container according to claim 13, further comprising a moving device that moves at least one of the holding device and the rotating member relatively to the other, wherein after the first closing control is executed, the control device executes a second closing control to control at least one of the closing device and the moving device so that the rotating member applies a force to the lid in a direction to close the lid while the rotating member is partially in contact with the lid. 15. A reagent kit comprising: a plurality of containers; and a packaging material that packages the plurality of containers, the plurality of containers each including: a container body, and a lid connected to the container body via a hinge and capable of opening and closing with respect to the container body, the plurality of containers being provided such that they are one-dimensionally disposed, with adjacent ones thereof connected to each other, the lid closed, and a reagent introduced in the container body."
  ],
  "description_excerpt": "The present disclosure relates to an opening apparatus for a container for receiving an analyte to be analyzed (a biological sample such as blood, urine, bodily fluid obtained with a nasopharyngeal swab, saliva, etc.) or a reagent, an analysis device for analyzing infectious viruses or genes contained in the analyte in the container, and a reagent kit usable in the analysis device.\n\nConventionally, there is an apparatus for analyzing a gene contained in an analyte through polymerase chain reaction (PCR) (for example, see Japanese Patent No. 4785862).\n\nPatent Literature PTL 1: Japanese Patent 4785862\n\nTechnical Problem In order to analyze genes through PCR, it is necessary for an operator who performs analysis to manually perform some of operations such as a reagent adjustment operation prior to PCR and an opening operation for a container for dispensing an analyte or a reagent into the container, and accordingly, the operator needs to be skilled. These operations are cumbersome, and the analysis takes a long time of about several hours, and there is a possibility that the operator may introduce variation into data, make mistakes, be infected, etc. Therefore, gene analysis through PCR is difficult to perform in medical institutions such as small- and medium-sized hospitals and clinics, and is mainly performed in large hospitals, examination centers, and hygiene laboratories.",
  "cpc": [
    "B25J 15/0033",
    "B67B 7/02",
    "B67B 7/16",
    "C12M 1/34",
    "C12M 41/14",
    "C12M 41/36",
    "C12M 41/48",
    "C12N 15/09",
    "C12Q 1/686",
    "G01N 2035/0405",
    "G01N 35/0099",
    "G01N 35/04"
  ],
  "ipc": [
    "B25J 15/00",
    "B67B 7/16",
    "C12M 1/34",
    "C12N 15/09",
    "C12Q 1/686",
    "G01N 35/00"
  ],
  "assignees": [
    "SHIMADZU CORP"
  ],
  "inventors": [
    "SASAYAMA TOMOKI",
    "HANAFUSA NOBUHIRO"
  ],
  "filing_date": "2021-09-07",
  "publication_date": "2023-12-07",
  "priority_date": "2020-10-26",
  "application_number": "US-202118033801-A",
  "family_id": "81384047"
}