Sugar mixtures and methods for production and use thereof

{
  "publication_number": "US9410216B2",
  "country": "US",
  "kind": "B2",
  "title": "Sugar mixtures and methods for production and use thereof",
  "abstract": "A sugar mixture comprising: monosaccharides; oligosaccharides in a ratio ≧0.06 to total saccharides; disaccharides in a ratio to total saccharides ≧0.05; pentose in a ratio to total saccharides ≧0.05; at least one alpha-bonded di-glucose; and at least one beta-bonded di-glucose. Also disclosed are methods to make and/or use such mixtures.",
  "claims": [
    "1. A de-acidified and de-salted sugar mixture, the de-acidified and de-salted sugar mixture comprising monosaccharide hydrolysates; (i) higher oligosaccharide hydrolysates comprising three or more sugar units; (ii) a ratio of disaccharide hydrolysates to total saccharides of ≧0.05 on a weight by weight basis; (iii) a ratio of pentose to total saccharides of ≧0.05 on a weight by weight basis; (iv) at least one alpha-bonded di-glucose; (v) at least one beta-bonded di-glucose; and (vi) a mineral acid to carbohydrate ratio of less than 0.01 on a weight by weight basis.",
    "2. A mixture according to claim 1, having a ratio of higher oligosaccharide hydrolysates to total saccharides of ≦0.2 on a weight by weight basis.",
    "3. A mixture according to claim 1, wherein a ratio of at least one of the alpha-bonded di-glucose and the beta-bonded di-glucose relative to total saccharides is ≧0.01 on a weight by weight basis.",
    "4. A mixture according to claim 3, wherein a ratio of at least one of the alpha-bonded di-glucose and the beta-bonded di-glucose relative to total saccharides is ≧0.03 on a weight by weight basis.",
    "5. A mixture according to claim 1, wherein the alpha-bonded di-glucose includes at least one member selected from the group consisting of maltose, isomaltose and trehalose.",
    "6. A mixture according to claim 1, wherein the beta-bonded di-glucose includes at least one member selected from the group consisting of gentiobiose, sophorose and cellobiose.",
    "7. A mixture according to claim 1, wherein the mineral acid to carbohydrate ratio is less than 0.005 on a weight by weight basis.",
    "8. A mixture according to claim 1, wherein the sugar mixture comprises oligosaccharide hydrolysates in a ratio to total saccharides of ≧0.06 on a weight by weight basis.",
    "9. A mixture according to claim 8, wherein the oligosaccharide hydrolysates comprise two or more sugar units.",
    "10. A mixture according to claim 1, wherein the sugar mixture further comprises a water-soluble organic compound impurity.",
    "11. A mixture according to claim 1, wherein the oligosaccharide hydrolysates to total carbohydrate ratio is less than 0.1 on a weight by weight basis.",
    "12. A method comprising: (a) providing a fermentor; and (b) fermenting a medium comprising a de-acidified and de-salted sugar mixture according to claim 1 in the fermentor to produce a fermentation product.",
    "13. A method according to claim 12, wherein the fermentation product includes at least one member selected from the group consisting of alcohols, carboxylic acids, amino acids, monomers for the polymer industry and proteins.",
    "14. A method according to claim 12, comprising processing the fermentation product to produce a consumer product.",
    "15. A method according to claim 12, wherein the fermentation product includes at least one member selected from the group consisting of ethanol, butanol, isobutanol, a fatty acid, a fatty acid ester, a fatty alcohol and biodiesel.",
    "16. A method according to claim 15, comprising processing of the fermentation product.",
    "17. The method of claim 12, further comprising converting the fermentation product to a consumer product, a precursor of a consumer product, or an ingredient of a consumer product produced.",
    "18. The method of claim 17, comprising converting the fermentation product to a consumer product.",
    "19. The method of claim 17, comprising converting the fermentation product to a consumer product, a precursor of a consumer product, or an ingredient of a consumer product, wherein the consumer product has a ratio of carbon-14 to carbon-12 of about 2.0×10 −13 or greater.",
    "20. The method of claim 17, comprising converting the fermentation product to a consumer product, wherein the consumer product further comprises an additional ingredient produced from a raw material other than lignocellulosic material.",
    "21. The method of claim 17, comprising converting the fermentation product to a consumer product, wherein the consumer product comprises a marker molecule at a concentration of at least 100 ppb.",
    "22. A method according to claim 12, wherein a sugar mixture prior to de-acidification and de-salting comprises 1.5 times more salt as compared to the de-acidified and de-salted sugar mixture.",
    "23. A method according to claim 12, wherein the sugar mixture further comprises a water-soluble organic compound impurity.",
    "24. A method according to claim 23, wherein the water-soluble organic compound impurity comprises multiple compounds.",
    "25. A method according to claim 23, wherein a sugar mixture prior to de-acidification and de-salting comprises 1.5 times more water-soluble organic compound impurity as compared to the de-acidified and de-salted sugar mixture.",
    "26. A de-acidified and de-salted sugar mixture, the de-acidified and de-salted sugar mixture comprising monosaccharide hydrolysates and oligosaccharide hydrolysates, wherein the oligosaccharide hydrolysates to total carbohydrate in the de-acidified and de-salted sugar mixture has a ratio of less than 0.15 on a weight by weight basis; wherein the de-acidified and de-salted sugar mixture is further characterized by having: (i) higher oligosaccharide hydrolysates comprising three or more sugar units; (ii) a ratio of disaccharide hydrolysates to total saccharides of ≧0.05 on a weight by weight basis; (iii) a ratio of pentose to total saccharides of ≧0.05 on a weight by weight basis; (iv) at least one alpha-bonded di-glucose; (v) at least one beta-bonded di-glucose; and (vi) sulfuric acid to carbohydrate ratio of less than 0.01 on a weight by weight basis.",
    "27. A mixture according to claim 26, wherein the oligosaccharide hydrolysates to total carbohydrate ratio is less than 0.1 on a weight by weight basis."
  ],
  "description_excerpt": "U.S. 61/358,894 filed 26 Jun. 2010 by Aharon EYAL and entitled “Fermentation Feedstock Precursor and Methods for the Production Thereof”; and\n\nU.S. 61/491,243 filed 30 May 2011 by Robert JANSEN et al. and entitled “Lignin Compositions, Systems and Methods for Processing Lignin and/or HCl”; and\n\nU.S. 61/500,169 filed 23 Jun. 2011 by Aharon EYAL et al. and entitled “Sugar Mixtures and Methods for Production and Use thereof”;\n\nU.S. 61/473,134 filed 7 Apr. 2011 by Aharon EYAL and entitled “Lignocellulose Conversion Processes and Products”; and\n\nU.S. 61/483,663 filed 7 May 2011 by Aharon EYAL and entitled “Lignocellulose Conversion Processes and Products”\n\nU.S. 61/483,777 filed 9 May 2011 by Robert JANSEN et al. and entitled “Hydrolysis Systems and Methods”; and\n\nU.S. 61/487,319 filed 18 May 2011 by Robert JANSEN et al. and entitled “Hydrolysis Systems and Methods”; and\n\nThis invention relates to sugars and production and use thereof.\n\nThe carbohydrate-conversion industry is large and rapidly increasing in size. Currently, about 100 million tons of carbohydrates are fermented annually, primarily to provide fuel-grade ethanol. This number is predicted to triple in the next decade.\n\nMillions of tons of carbohydrates are also fermented every year to provide food and feed products, such as citric acid and lysine. Also large and increasing is fermentation to produce other products, such as monomers for the polymer industry, e.g. lactic acid for the production of polylactide.",
  "cpc": [
    "C13K 1/02",
    "A23V 2002/00",
    "A23V 2250/60",
    "C01B 7/0737",
    "C12M 1/00",
    "C12N 1/22",
    "C12P 19/02",
    "C12P 19/14",
    "C12P 2203/00",
    "C12P 7/10",
    "C12P 7/64",
    "C13B 50/00",
    "C13K 11/00",
    "C13K 13/00",
    "C13K 13/002",
    "C13K 3/00",
    "C13K 5/00",
    "C13K 7/00",
    "Y02E 50/10",
    "Y02E 50/13",
    "Y02E 50/16",
    "Y02E 50/17"
  ],
  "ipc": [
    "C08F 10/02",
    "C08F 10/06",
    "C08F 20/12",
    "C08G 63/02",
    "C08G 63/08",
    "C09D 133/08",
    "C12P 13/04",
    "C12P 21/00",
    "C12P 7/02",
    "C12P 7/04",
    "C12P 7/06",
    "C12P 7/14",
    "C12P 7/16",
    "C12P 7/40",
    "C12P 7/64",
    "C13B 50/00",
    "C13K 13/00",
    "C12P 19/02",
    "C12P 19/14",
    "C12P 7/10",
    "C13K 1/02"
  ],
  "assignees": [
    "Virdia LLC"
  ],
  "inventors": [
    "Aharon Meir Eyal",
    "Robert P. Jansen",
    "Revital Mali",
    "Asher Vitner"
  ],
  "filing_date": "2011-06-26",
  "publication_date": "2016-08-09",
  "grant_date": "2016-08-09",
  "priority_date": "2010-06-26",
  "application_number": "US-201113378657-A",
  "family_id": "45371892",
  "cited_by_count": 34,
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