CXCR3 receptor

{
  "id": "MLC-T-AGR-001656",
  "term": "CXCR3 receptor",
  "field": "Agriculture and food",
  "definition": "CD183 is a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (interferon-g-inducible 10 kDa protein), Mig (monokine induced by interferon-g) and I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to CD183 induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Inhibition by Bordetella pertussis toxin suggests that heterotrimeric G protein of the Gi-subclass couple to CD183. A hallmark of CD183 is its prominent expression in in vitro cultured effector/memory T cells, and in T cells present in many types of inflamed tissues. In addition, IP10, Mig and I-TAC are commonly produced by local cells in inflammatory lesion, suggesting that CD183 and its chemokines participate in the recruitment of inflammatory cells.",
  "synonyms": [
    "C-X-C chemokine receptor type 3",
    "CD183 antigen",
    "CKR-L2",
    "CMKAR3",
    "CXC chemokine receptor 3",
    "CXCR3-A",
    "CXCR3-B",
    "GPR9 (G-protein coupled receptor 9)",
    "I-TAC receptor",
    "IP-10 receptor",
    "MIG-R (Mig receptor)",
    "chemokine (C-X-C motif) receptor 3",
    "chemokine (C-X-C) receptor 3",
    "interferon-inducible protein 10 receptor"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "chemokine receptors",
    "chemokine CXCL4",
    "chemokine CXCL9",
    "chemokine CXCL10",
    "chemokine CXCL11"
  ],
  "references": [
    "National Cancer Institute Thesaurus",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "receptor CXCR3"
  },
  "url": "https://mlchart.com/terminology/agriculture/cxcr3-receptor/"
}