patch-clamp technique

{
  "id": "MLC-T-AGR-004754",
  "term": "patch-clamp technique",
  "field": "Agriculture and food",
  "definition": "An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.",
  "synonyms": [
    "patch-clamp techniques",
    "voltage-clamp technique"
  ],
  "subject": "Research, Technology, Methods",
  "see_also": [
    "laboratory techniques"
  ],
  "references": [
    "Medical Subject Headings 2013",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "técnica de patch-clamp"
  },
  "url": "https://mlchart.com/terminology/agriculture/patch-clamp-technique/"
}