Placental growth factor
Term · Agriculture and food · MLC-T-AGR-004972
An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.
| Identifier | MLC-T-AGR-004972 |
|---|---|
| Field | Agriculture and food |
| Subject | Fields of Study |
| References | Medical Subject Headings 2017; NAL Agricultural Thesaurus and Glossary (CC BY 4.0) |
| See also | Pregnancy proteins; Vascular endothelial growth factors; Angiogenesis |
| Translations | Spanish: factor de crecimiento placentario |
Record as JSON
{
"id": "MLC-T-AGR-004972",
"term": "Placental growth factor",
"field": "Agriculture and food",
"definition": "An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.",
"subject": "Fields of Study",
"see_also": [
"pregnancy proteins",
"vascular endothelial growth factors",
"angiogenesis"
],
"references": [
"Medical Subject Headings 2017",
"NAL Agricultural Thesaurus and Glossary"
],
"translations": {
"es": "factor de crecimiento placentario"
},
"url": "https://mlchart.com/terminology/agriculture/placental-growth-factor/"
}
Record 4,906 of 6,798 in Agriculture and food terminology (MLC-0114). Request the full dataset.