Vascular endothelial growth factor A

{
  "id": "MLC-T-AGR-006647",
  "term": "Vascular endothelial growth factor A",
  "field": "Agriculture and food",
  "definition": "The original member of the family of endothelial cell growth factors referred to as vascular endothelial growth factors. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as \"tumor angiogenesis factor\" and \"vascular permeability factor\". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating vasodilation via nitric oxide-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.",
  "abbreviation": "VEGF-A",
  "synonyms": [
    "GD-VEGF",
    "glioma-derived vascular endothelial cell growth factor",
    "vascular endothelial growth factor-A",
    "vascular permeability factor",
    "vasculotropin"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "vascular endothelial growth factors"
  ],
  "references": [
    "Medical Subject Headings 2014",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "factor A de crecimiento endotelial vascular"
  },
  "url": "https://mlchart.com/terminology/agriculture/vascular-endothelial-growth-factor-a/"
}