prions

{
  "id": "MLC-T-AGR-005174",
  "term": "prions",
  "field": "Agriculture and food",
  "definition": "Small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc; the cellular isoform is PrPC. The primary amino acid sequence of the two isoforms is identical. Among diseases caused by prions are scrapie, bovine spongiform encephalopathy, and Creuzfeldt-Jakob Syndrome.",
  "synonyms": [
    "PrP proteins",
    "prion proteins"
  ],
  "subject": "Fields of Study",
  "see_also": [
    "proteins",
    "prion diseases",
    "food pathogens",
    "PrPC proteins",
    "PrPSc proteins"
  ],
  "references": [
    "Medical Subject Headings",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "priones"
  },
  "url": "https://mlchart.com/terminology/agriculture/prions/"
}