Unfolded protein response

{
  "id": "MLC-T-AGR-006593",
  "term": "Unfolded protein response",
  "field": "Agriculture and food",
  "definition": "A cellular response to environmental insults that cause disruptions in protein folding and/or accumulation of defectively folded protein in the endoplasmic reticulum. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of apoptosis.",
  "subject": "Fields of Study",
  "see_also": [
    "post-translational modification",
    "stress response",
    "protein unfolding",
    "endoplasmic reticulum stress",
    "protein folding"
  ],
  "references": [
    "Medical Subject Headings",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "respuesta de proteína mal plegada"
  },
  "url": "https://mlchart.com/terminology/agriculture/unfolded-protein-response/"
}