Acutely Toxic Effect

{
  "id": "MLC-T-ENV-000447",
  "term": "Acutely Toxic Effect",
  "field": "Environment",
  "definition": "A chemical substance produces acutely toxic effects if it kills within a short time period (usually 14 days):(1) At least 50 percent of the exposed mammalian test animals following oral administration of a single dose of the test substance at 25 milligrams or less per kilogram of body weight (LD50).(2) At least 50 percent of the exposed mammalian test animals following dermal administration of a single dose of the test substance at 50 milligrams or less per kilogram of body weight (LD50).(3) At least 50 percent of the exposed mammalian test animals following administration of the test substance for 8 hours or less by continuous inhalation at a steady concentration in air at 0.5 milligrams or less per liter of air (LC50).",
  "references": [
    "40 CFR 721.3 (CFR 2013)"
  ],
  "url": "https://mlchart.com/terminology/environment/acutely-toxic-effect/"
}