Adverse Outcome Pathway

{
  "id": "MLC-T-ENV-000615",
  "term": "Adverse Outcome Pathway",
  "field": "Environment",
  "definition": "1. Model that identifies the sequence or molecular and cellular events required to produce a toxic effect when an organism is exposed to a substance.\n\n2. Conceptual framework that portrays existing knowledge concerning the linkage between a direct molecular initiating event and an adverse outcome, at a level of biological organization relevant to risk assessment.",
  "abbreviation": "AOP",
  "references": [
    "National Toxicology Program",
    "EPA 2013"
  ],
  "url": "https://mlchart.com/terminology/environment/adverse-outcome-pathway/"
}