Age dependent adjustment factor

{
  "id": "MLC-T-ENV-000711",
  "term": "Age dependent adjustment factor",
  "field": "Environment",
  "definition": "In cases where age-related differences in toxicity occur, differences in both toxicity and exposure need to be integrated across all relevant age intervals, by the use of age dependent potency adjustment factors (ADAFs). This is a departure from the way cancer risks have historically been calculated based upon the premise that risk is proportional to the daily average of the long-term adult dose.",
  "abbreviation": "ADAF",
  "subject": "Health and safety",
  "references": [
    "Exposure Factors Handbook: Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/age-dependent-adjustment-factor/"
}