MLchartDataset catalogue

Alkylating Activity

Term · Environment · MLC-T-ENV-001061

Alkylating Activity in biological systems is typically a process of covalent bonding in which a chemical substance replaces hydrogen atom(s) in biologically active molecules with alkyl radical(s), hindering proper function. DNA alkylation results in strand cross-linking and can inhibit DNA replication.

Table 1. Record
IdentifierMLC-T-ENV-001061
FieldEnvironment
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ENV-001061",
  "term": "Alkylating Activity",
  "field": "Environment",
  "definition": "Alkylating Activity in biological systems is typically a process of covalent bonding in which a chemical substance replaces hydrogen atom(s) in biologically active molecules with alkyl radical(s), hindering proper function. DNA alkylation results in strand cross-linking and can inhibit DNA replication.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/alkylating-activity/"
}

Record 1,061 of 30,736 in Environment terminology (MLC-0121). Request the full dataset.