Cholera

{
  "id": "MLC-T-ENV-004931",
  "term": "Cholera",
  "field": "Environment",
  "definition": "(A disease caused by) a toxic secreted by Vibrio cholerae, which is a natural bacterial enterotoxin consisting of major components heavy A- and light B peptides (choleragenoid) that initiates a signaling cascade in intestinal epithelial cells causing a dysfunction of chloride channels, loss of water, and diarrhea. B peptide anchors the protein to epithelia; A peptide enters the cytoplasm and activates adenylate cyclase.",
  "references": [
    "NIH National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/cholera/"
}