Insulin

{
  "id": "MLC-T-ENV-014583",
  "term": "Insulin",
  "field": "Environment",
  "definition": "A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production ( GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).",
  "references": [
    "NLM Medical Subject Headings (MeSH)"
  ],
  "url": "https://mlchart.com/terminology/environment/insulin/"
}