Lactate Dehydrogenase

{
  "id": "MLC-T-ENV-015258",
  "term": "Lactate Dehydrogenase",
  "field": "Environment",
  "definition": "1. A family of homotetrameric cytoplasmic enzymes involved in the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.\n\n2. One of a group of enzymes found in the blood and other body tissues and involved in energy production in cells. An increased amount of lactate dehydrogenase in the blood may be a sign of tissue damage and some types of cancer or other diseases.",
  "abbreviation": "LDH",
  "references": [
    "National Cancer Institute Thesaurus",
    "National Cancer Institute Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/lactate-dehydrogenase/"
}