MLchartDataset catalogue

Non-stop decay

Term · Environment · MLC-T-ENV-019041

In eukaryotes, the non-stop decay mechanism recognizes and degrades mRNAs that lack a stop codon. It releases ribosomes stalled at the 3' end of a mRNA and stimulates the exosome to rapidly degrade the transcript.

Table 1. Record
IdentifierMLC-T-ENV-019041
FieldEnvironment
SubjectBiological substances
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ENV-019041",
  "term": "Non-stop decay",
  "field": "Environment",
  "term_source": "Non-Stop Decay",
  "definition": "In eukaryotes, the non-stop decay mechanism recognizes and degrades mRNAs that lack a stop codon. It releases ribosomes stalled at the 3' end of a mRNA and stimulates the exosome to rapidly degrade the transcript.",
  "subject": "Biological substances",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/non-stop-decay/"
}

Record 18,532 of 29,894 in Environment terminology (MLC-0121). Request the full dataset.