MLchartDataset catalogue

Post-Translational Protein Processing

Term · Environment · MLC-T-ENV-021721

1. The enzymatic processing of a polypeptide chain after translation from messenger RNA and after peptide bond formation has occurred. Examples include glycosylation, acylation, limited proteolysis, phosphorylation, isoprenylation. (On-line Medical Dictionary)

2. Any of various enzymatically catalyzed post-translational modifications of peptides or proteins in the cell of origin. These modifications include carboxylation; hydroxylation; acetylation; phosphorylation; methylation; glycosylation; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.

Table 1. Record
IdentifierMLC-T-ENV-021721
FieldEnvironment
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0); NLM Medical Subject Headings (MeSH)
Record as JSON
{
  "id": "MLC-T-ENV-021721",
  "term": "Post-Translational Protein Processing",
  "field": "Environment",
  "definition": "1. The enzymatic processing of a polypeptide chain after translation from messenger RNA and after peptide bond formation has occurred. Examples include glycosylation, acylation, limited proteolysis, phosphorylation, isoprenylation. (On-line Medical Dictionary)\n\n2. Any of various enzymatically catalyzed post-translational modifications of peptides or proteins in the cell of origin. These modifications include carboxylation; hydroxylation; acetylation; phosphorylation; methylation; glycosylation; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.",
  "references": [
    "National Cancer Institute Thesaurus",
    "NLM Medical Subject Headings (MeSH)"
  ],
  "url": "https://mlchart.com/terminology/environment/post-translational-protein-processing/"
}

Record 21,721 of 30,736 in Environment terminology (MLC-0121). Request the full dataset.