Topoisomerase Interaction

{
  "id": "MLC-T-ENV-028234",
  "term": "Topoisomerase Interaction",
  "field": "Environment",
  "definition": "Topoisomerase Interaction involves temporary non-covalent binding through intermolecular physical forces of attraction and spatial complementarity with enzymes that change the degree of supercoiling in DNA by cutting one or both strands. Type I topoisomerases cut only one strand of DNA, while type II topoisomerases cut both strands of DNA.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/topoisomerase-interaction/"
}