X-Chromosome Inactivation

{
  "id": "MLC-T-ENV-030619",
  "term": "X-Chromosome Inactivation",
  "field": "Environment",
  "definition": "A human early embryonic event in which in any given cell one of a female's two X chromosomes becomes inactivated and converted into a Barr body. After inactivation has occurred, all descendants of that cell have the same inactivated X chromosome. Thus, X-inactivation creates cell clones with differing effective gene content. An organism whose cells vary in effective gene content and hence in the expression of a trait, is called a genetic mosaic.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/environment/x-chromosome-inactivation/"
}