Acellular dermal matrix

{
  "id": "MLC-T-ONC-009599",
  "term": "Acellular dermal matrix",
  "field": "Oncology and biomedicine",
  "definition": "An allograft composed of sterile, decellularized regenerative dermal tissue matrix with soft tissue reconstructive, regenerative and transplantation purposes. The acellular dermal matrix (ADM) is composed of the dermal layer and extracellular matrix of human or animal skin and in which the epidermal layer is removed, The ADM retains native growth factors, collagen and elastin. The ADM supports tissue expanders or implants for soft tissue reconstruction or to aid in wound healing, and allows for rapid cellular proliferation and infiltration, integration of mesenchymal cells into the matrix and re-vascularization. This facilitates surgical reconstruction and protects against wound exposure and wound infection.",
  "synonyms": [
    "ADM"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/acellular-dermal-matrix/"
}