Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: A (3,095)

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A-101 topical solutionA proprietary topical formulation consisting of a high-concentration of hydrogen peroxide (H2O2), with...
A2A/A2B adenosine receptor antagonist INCB106385An orally bioavailable antagonist of both the immunomodulatory checkpoint molecules adenosine A2A receptor...
A2A/A2B adenosine receptor antagonist YZJ-5053An orally bioavailable antagonist of both the immunomodulatory checkpoint molecules adenosine A2A receptor...
A2AR antagonist EXS21546An orally bioavailable immune checkpoint inhibitor and antagonist of the adenosine A2A receptor (A2AR...
A33A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are...
A6A substance being studied in the treatment of cancer. A6 is a small piece of a protein called urokinase (an...
AAPAn enzyme that is normally found in healthy kidneys. It may be found at high levels in the urine when there...
AAT deficiencyAn inherited condition in which the body either does not make enough of a protein called alpha-1 antitrypsin...
abacavir sulfateA sulfate salt form of abacavir, a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent...
abagovomabA murine IgG1 monoclonal anti-idiotype antibody, containing a variable antigen-binding region that...
abaloparatideA 34 amino acid synthetic analog of human parathyroid hormone-related protein (PTHrP) (PTHrP(1-34) analog)...
abarelixA drug used to reduce the amount of testosterone made in patients with advanced symptomatic prostate cancer...
abataceptA soluble fusion protein consisting of the extracellular domain of human cytotoxic T lymphocyte-associated...
abazistobartA recombinant immunoglobulin G4 (IgG4) kappa monoclonal antibody directed against the negative...
ABBV-221An intravenously-administered agent capable of modulating the activity of epidermal growth factor receptor...
ABCA1 pathwayDescribes a group of proteins in a cell that work together to help remove extra cholesterol and certain fats...
ABCD ratingA staging system for prostate cancer that uses ABCD. “A” and “B” refer to cancer that is confined to the...
ABCG2 substrateAny substance that is subjected to cellular efflux by the ABC family transport protein, broad substrate...
abdomenThe area of the body that contains the pancreas, stomach, intestines, liver, gallbladder, and other organs.
abdominalHaving to do with the abdomen, which is the part of the body between the chest and the hips that contains the...
abdominal breathingA relaxation technique in which a person focuses on taking slow, deep breaths. Abdominal breathing involves...
abdominal ultrasoundA procedure used to examine the organs in the abdomen. An ultrasound transducer (probe) is pressed firmly...
abdominal wallThe layers of skin, muscles, fat, and other tissues that surround and protect the organs inside the abdomen...
abdominal x-rayAn x-ray of the organs inside the abdomen. An x-ray is a type of radiation that can pass through the body and...
abdominoperineal resectionSurgery to remove the anus, the rectum, and part of the sigmoid colon through an incision made in the...
AbecmaA treatment used for adults with multiple myeloma that came back or did not get better after treatment with...
AbegrinA substance being studied in the treatment of some types of cancer and other conditions. Abegrin binds to a...
abelacimabA human anti-factor XI (FXI) monoclonal antibody, with potential anti-thrombotic activity. Upon...
abemaciclibA drug used alone or with other drugs to treat adults with certain types of hormone-receptor positive...
abequolixronAn orally bioavailable agonist of the nuclear receptor liver X receptor beta (LXRbeta; NR1H2; LXR-b), with...
aberrant crypt fociClusters of abnormal tube-like glands in the lining of the colon and rectum. Aberrant crypt foci form before...
abexinostat tosylateThe tosylate salt form of abexinostat, an orally bioavailable hydroxamate-based pan-inhibitor of histone...
ABI-007A form of the anticancer drug paclitaxel that is used alone or with other drugs to treat certain types of...
abipapogene suvaplasmidA therapeutic DNA vaccine composed of three parts, one encodes the E6/E7 fusion protein of human...
abirateroneA steroidal compound with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid...
abiraterone acetateA drug used with other drugs to treat prostate cancer that has spread to other parts of the body. Abiraterone...
abiraterone amorphous solid dispersion formulation DST-2970An orally bioavailable, amorphous solid dispersion formulation of the steroidal compound abiraterone, with...
abiraterone decanoate depotA depot formulation containing the decanoate ester of abiraterone, a steroidal compound with antiandrogen...
abiraterone/prednisone regimenA regimen consisting of abiraterone and prednisone that can be used for the treatment of prostate cancer and...
abituzumabA humanized monoclonal antibody directed against the human alpha v integrin subunit with potential...
abivertinibAn orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with...
abivertinib maleate anhydrousThe maleate salt form of abivertinib, an orally available, irreversible, epidermal growth factor receptor...
ablationIn medicine, the removal or destruction of a body part or tissue or its function. Ablation may be performed...
abnormalNot normal. Describes a state, condition, or behavior that is unusual or different from what is considered...
ABO blood group systemA system used to group human blood into different types, based on the presence or absence of certain markers...
ABR testA test used to detect some types of hearing loss, such as hearing loss caused by injury or tumors that affect...
AbraxaneA form of the anticancer drug paclitaxel that is used alone or with other drugs to treat certain types of...
Abrikossoff tumorA rare type of soft tissue tumor that usually begins in Schwann cells (cells that hold nerve cells in place)...
abscessAn enclosed collection of pus in tissues, organs, or confined spaces in the body. An abscess is a sign of...
abscopal effectDescribes the shrinking or disappearance of tumors in parts of the body that were not the direct target of...
absolute neutrophil countA measure of the number of neutrophils in the blood. Neutrophils are a type of white blood cell. They help...
absolute riskA measure of the risk of a certain event happening. In cancer research, absolute risk is the likelihood that...
absorbable adhesion barrier gelAn isotonic, sterile, absorbable adhesion barrier gel composed of polyethylene oxide and sodium...
absorbable fibrin sealant patchA sterile, absorbable surgical sealing patch composed of an equine collagen sponge coated with the...
absorbable gelatin spongeA sterile hemostatic agent composed of purified porcine-derived gelatin. In regional chemotherapy, absorbable...
absorbable modified polymer hemostatic powderA hemostatic powder composed of hydrophilic, absorbable modified polymers (AMPs) derived from plant starch...
absorptionThe process of taking nutrients from the digestive system into the blood so they can be used in the body.
ABT-263A substance being studied in the treatment of lymphomas and other types of cancer. It blocks some of the...
ABT-510A substance being studied in the treatment of cancer. It is a type of angiogenesis inhibitor.
ABT-751A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
ABT-869A substance being studied in the treatment of several types of cancer. ABT-869 blocks the action of several...
ABT-888A substance being studied in the treatment of breast cancers caused by mutations (changes) in the BRCA1 and...
ABVDAn abbreviation for a chemotherapy combination used to treat Hodgkin lymphoma. It includes the drugs...
ABVD regimenAn abbreviation for a chemotherapy combination used to treat Hodgkin lymphoma. It includes the drugs...
ABVEAn abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin...
ABVE regimenAn abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin...
ABVE-PCAn abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin...
ABVE-PC regimenAn abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin...
ABX-EGFA drug used alone or with other drugs to treat certain types of colorectal cancer that have spread to other...
ACAn abbreviation for a chemotherapy combination used with other types of therapy to treat breast cancer...
AC regimenAn abbreviation for a chemotherapy combination used with other types of therapy to treat breast cancer...
acadesineA 5-aminoimidazole-4-carboxamide (AICA) riboside, a purine nucleoside analog, and a nucleotide biosynthesis...
Acai Berry JuiceA juice product obtained from the fruit of the acai palm tree (Euterpe oleracea) with anti-inflammatory...
acalabrutinibAn orally available inhibitor of Bruton tyrosine kinase (BTK) with potential antineoplastic activity. Upon...
acalabrutinib maleate monohydrateA drug used alone to treat adults with chronic lymphocytic leukemia or small lymphocytic lymphoma and adults...
acalisibAn inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide-3...
acapatamabA half-life extended (HLE), bispecific T-cell engager (BiTE) antibody composed of two single-chain variable...
ACAPHAA mixture of six herbs that has been used in China to prevent and treat diseases such as lung and esophageal...
acarboseA pseudotetrasaccharide and inhibitor of alpha-glucosidase and pancreatic alpha-amylase with...
AcasunlimabA recombinant, Fc-silenced immunoglobulin G1 (IgG1) bispecific antibody targeting both the human programmed...
accelerated approvalAn official process that allows a new drug to be approved by the U.S. Food and Drug Administration (FDA)...
accelerated partial-breast irradiationA type of radiation therapy given only to the part of the breast that has cancer in it. Accelerated...
accelerated phase chronic myelogenous leukemiaA phase of chronic myelogenous leukemia in which the disease is progressing. In this phase, 10% to 19% of the...
accelerated radiation therapyRadiation treatment in which the total dose of radiation is given over a shorter period of time (fewer days)...
accelerated-fraction radiation therapyRadiation treatment in which the total dose of radiation is divided into small doses and the treatments are...
AccolateA drug used to prevent and treat symptoms of asthma. It blocks substances that cause inflammation in the...
ACD geneA gene that makes a protein involved in protecting and maintaining telomeres (the ends of chromosomes)...
ACE inhibitorA drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent. Also...
acebilustatAn orally bioavailable, small molecule inhibitor of the enzyme leukotriene A4 hydrolase (LTA4H), with...
acellular cadaveric dermal matrixA human dermis-derived allograft material. Acellular cadaveric dermal matrix (ACDM) is derived from human...
acellular dermal matrixAn allograft composed of sterile, decellularized regenerative dermal tissue matrix with soft tissue...
acenocoumarolA 4-hydroxycoumarin derivative with anticoagulant activity. As a vitamin K antagonist, acenocoumarol inhibits...
acetaminophenA drug that reduces pain and fever (but not inflammation). It belongs to the family of drugs called...
acetateA form of acetic acid (an acid found in vinegar).
acetazolamideA sulfonamide derivative with diuretic, antiglaucoma, and anticonvulsant properties. Acetazolamide is a...
acetazolamide sodiumThe sodium salt of acetazolamide, a nonbacteriostatic sulfonamide derivative with diuretic and anticonvulsant...
acetic acidAn acid found in vinegar. Acetic acid is also used to dissolve substances needed to make some medicines and...
acetohexamideAn intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Acetohexamide is...
acetoneA chemical substance found naturally in small amounts in plants, trees, volcanoes, and forest fires. Acetone...
acetyl groupA small molecule made of two carbon, three hydrogen, and one oxygen atoms. Acetyl groups are added to or...
acetylationA chemical reaction in which a small molecule called an acetyl group is added to other molecules. Acetylation...
acetylcholineA chemical made by some types of nerve cells. It is used to send messages to other cells, including other...
acetylcysteineA drug usually used to reduce the thickness of mucus and ease its removal. It is also used to reverse the...
acetylglucosaminyltransferase V inhibitor PhOx430An inhibitor of the glycosyltransferase N-Acetylglucosaminyltransferase V (GnT-V), with potential...
acetyl-L-carnitineA form of the natural substance carnitine that is being studied as a way to prevent tissue damage caused by...
acetyl-L-carnitine hydrochlorideA form of the natural substance carnitine that is being studied as a way to prevent tissue damage caused by...
ACFClusters of abnormal tube-like glands in the lining of the colon and rectum. ACF form before colorectal...
achlorhydriaA lack of hydrochloric acid in the digestive juices in the stomach. Hydrochloric acid helps digest food.
acidA chemical that gives off hydrogen ions in water and forms salts by combining with certain metals. Acids have...
acid-base balanceIn medicine, the state of having the right amount of acid and base in the blood and other body fluids...
acid-base equilibriumIn medicine, the state of having the right amount of acid and base in the blood and other body fluids...
acidificationThe process of making or becoming an acid. An acid is a substance that gives off hydrogen ions in water and...
acidityDescribes the amount of acid in a substance. An acid is a chemical that gives off hydrogen ions in water and...
acimtamigA tetravalent bispecific antibody directed against human CD30 and the human low affinity IgG Fc region...
acinterferon alfaA proprietary recombinant protein highly resembling human interferon alpha 2b (IFN-a2b), with potential...
acitretinA substance that is used in the prevention of cancer and in the treatment of psoriasis. It belongs to the...
acivicinA modified amino acid and structural analog of glutamine. Acivicin inhibits glutamine amidotransferases in...
aclarubicinAn oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces...
ACN53A substance that has been studied in the treatment of some types of cancer. ACN53 is a weakened adenovirus...
acneA disorder of the skin in which oil glands and hair glands become inflamed.
acneiform dermatitisA skin condition that causes small, raised, acne-like bumps to form, usually on the face, scalp, chest, and...
acneiform eruptionA skin condition that causes small, raised, acne-like bumps to form, usually on the face, scalp, chest, and...
acneiform rashA skin condition that causes small, raised, acne-like bumps to form, usually on the face, scalp, chest, and...
acodazoleA synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in...
acolbifene hydrochlorideA substance being studied in the prevention of breast cancer in women at high risk of breast cancer...
acoramidisA potent, highly selective, orally bioavailable transthyretin (TTR) stabilizer with potential...
acousticHaving to do with sound or hearing.
acoustic coupling fluidA brain mimicking fluid with an attenuation coefficient similar to that found in the adult human brain, which...
acoustic neurofibromatosisA genetic condition in which tumors form on the nerves of the inner ear and cause loss of hearing and...
acoustic neuromaA benign (not cancer) tumor that forms on the nerves in the inner ear and can affect hearing and balance...
acquired immunityA type of immunity that develops when a person’s immune system responds to a foreign substance or...
acquired immunodeficiency syndromeA disease caused by the human immunodeficiency virus (HIV). People with acquired immunodeficiency syndrome...
acquired pure red cell aplasiaA rare disorder in which the bone marrow makes almost no red blood cells. It may be caused by infection or by...
acquired thrombotic thrombocytopenic purpuraA rare condition in which blood clots form in small blood vessels throughout the body. These clots can block...
acral lentiginous melanomaA rare type of melanoma that occurs in areas of the body that are usually not exposed to sunlight, such as...
acral melanomaA rare type of melanoma that occurs in areas of the body that are usually not exposed to sunlight, such as...
acridine carboxamideA substance being studied in the treatment of cancer. It is a type of topoisomerase inhibitor. Also called...
acrochordonA common benign (not cancer) skin growth that appears as a small, raised, brown or skin-colored bump that may...
acromegalyA condition in which the pituitary gland makes too much growth hormone after normal growth of the skeleton is...
acrylonitrileA substance used to make plastics, rubber, and textiles. Being exposed to acrylonitrile may increase the risk...
ACSS2 inhibitor MTB-9655An orally bioavailable small molecule inhibitor of the enzyme human acetyl coenzyme A synthetase short chain...
AC-TAn abbreviation for a chemotherapy combination used to treat breast cancer. It includes the drugs doxorubicin...
AC-T regimenAn abbreviation for a chemotherapy combination used to treat breast cancer. It includes the drugs doxorubicin...
AC-Taxol regimenAn abbreviation for a chemotherapy combination used to treat breast cancer. It includes the drugs doxorubicin...
ActemraA drug used to treat adults and children aged 2 years and older with severe or life-threatening cytokine...
ACTHA hormone made in the pituitary gland. ACTH acts on the outer part of the adrenal gland to control its...
ACTH antagonist CRN04894An orally bioavailable nonpeptide antagonist of the adrenocorticotropic hormone (ACTH) receptor (ACTHR...
AC-TH regimenAn abbreviation for a chemotherapy combination used to treat breast cancer. It includes the drugs doxorubicin...
ACTHomaA rare tumor that makes the hormone adrenocorticotropin (ACTH), which causes the adrenal glands to make too...
ActinexA drug put on the skin to treat growths caused by sun exposure. A form of Actinex that is taken by mouth is...
actinic keratosisA thick, scaly patch of skin that may become cancer. It usually forms on areas exposed to the sun, such as...
actinium Ac 225 DOTATATE RYZ101A radioconjugate consisting of the somatostatin analog tyrosine-3-octreotate (Tyr3-octreotate or TATE)...
actinium Ac 225 FPI-2059A radioconjugate consisting of a neurotensin receptor type 1 (NTSR1)-targeting small molecule antagonist...
actinium Ac 225 FPI-2068A radioimmunoconjugate composed of FPI-2053, a humanized bispecific antibody targeting epidermal growth...
actinium Ac 225 lintuzumabA radioimmunoconjugate consisting of the humanized monoclonal antibody lintuzumab conjugated to the...
actinium Ac 225 PSMA-R2A radioconjugate composed of PSMA-R2, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
actinium Ac 225 rosopatamab tetraxetanA radioimmunoconjugate consisting of a humanized monoclonal antibody directed against prostate specific...
actinium Ac 225 vofatamabA radioimmunoconjugate containing vofatamab, a human immunoglobulin G1 (IgG1) monoclonal antibody directed...
actinium Ac 225 zadavotide guraxetanA radioconjugate composed of zadavotide guraxetan, a human prostate-specific membrane antigen...
actinium Ac 225-ABD147A radioimmunoconjugate consisting of ABD147, an antibody fragment directed against the tumor-associated...
actinium Ac 225-DOTA-anti-CEA monoclonal antibody M5AA radioimmunoconjugate comprised of M5A, a humanized monoclonal antibody directed against carcinoembryonic...
Actinium Ac 225-DOTA-DaratumumabA radioimmunoconjugate containing daratumumab, a human immunoglobulin G1 kappa (IgG1k) monoclonal antibody...
actinium Ac 225-DOTA-h11B6 JNJ-69086420A radioimmunoconjugate containing h11B6, a humanized immunoglobulin G1 (IgG1) monoclonal antibody that...
actinium Ac 225-DOTA-MTI-201A radioconjugate composed of a melanocyte-stimulating hormone receptor (MSHR; melanocortin-1 receptor; MC1R...
actinium Ac 225-FL-020A radioconjugate composed of FL-020, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
actinium Ac 225-FPI-1434A radioconjugate consisting of veligrotug, a humanized monoclonal antibody directed against insulin-like...
actinium Ac 225-PSMA-trilliumA radioconjugate composed of PSMA-trillium, a human prostate-specific membrane antigen (PSMA)-targeting small...
actinium Ac-225An alpha-emitting radioisotope of actinium with a half-life of 10 days.
actinomycin DA drug that comes from the bacterium Streptomyces parvulus and is used alone or with other drugs to treat...
action studyIn cancer prevention clinical trials, a study that focuses on finding out whether actions people take can...
ActiqA drug used to treat severe pain in people with chronic conditions, such as cancer, who have not gotten...
ActivaseA form of tissue plasminogen activator that is made in the laboratory. It helps dissolve blood clots and is...
activateIn biology, to stimulate a cell in a resting state to become active. This causes biochemical and functional...
activated charcoalCarbon that has been treated to create small, low-volume pores that increase the surface area available for...
activated marrow infiltrating lymphocytesA preparation of cells, which consists of autologous marrow infiltrating lymphocytes (MILs), that are...
activated polyethylene glycol/polyethyleneimine-based surgical sealantA surgical sealant composed of activated polyethylene glycol (PEG) and polyethyleneimine (PEI) that can be...
active pharmaceutical ingredientThe main ingredient in a medicine that causes the desired effect of the medicine. Some medicines contain more...
active surveillanceClosely watching a patient’s condition but not giving any treatment unless there are changes in test results...
active treatmentIn a clinical trial, a positive control group that receives a known, proven active intervention.
activin Type 2B receptor Fc fusion protein STM 434A soluble fusion protein containing the extracellular domain of the activin receptor type 2B (ACVR2B or...
activin type IIA receptor Fc fusion protein KER-050A recombinant fusion protein composed of a modified form of the ligand-binding domain of the human...
activities of daily livingThe tasks of everyday life. These activities include eating, dressing, getting into or out of a bed or chair...
ActosA drug that is used to treat type 2 diabetes and is being studied in the prevention of head and neck cancer...
AC-T-TAn abbreviation for a chemotherapy combination used to treat breast cancer. It includes the drugs doxorubicin...
AC-T-T regimenAn abbreviation for a chemotherapy combination used to treat breast cancer. It includes the drugs doxorubicin...
acupointA specific spot on the body where an acupuncture needle may be inserted to control pain and other symptoms...
acupressureThe application of pressure or localized massage to specific sites on the body to control symptoms such as...
acupunctureThe technique of inserting thin needles through the skin at specific points on the body to control pain and...
acupuncture needleA stainless steel needle that is slightly thicker than a human hair. Acupuncture needles are inserted through...
acupuncture pointA specific spot on the body where an acupuncture needle may be inserted to control pain and other symptoms...
acupuncture point injectionA procedure in which drugs, vitamins, herbal extracts, or other fluids are injected into the body at an...
acupuncture-like transcutaneous electrical nerve stimulationA procedure in which mild electric currents are applied to certain acupuncture points (spots on the body...
acupuncturistA person trained in acupuncture (therapy that uses thin needles inserted through the skin at specific points...
acustimulationMild electrical stimulation of acupuncture points to control symptoms such as nausea and vomiting.
acuteSymptoms or signs that begin and worsen quickly; not chronic.
acute bacterial prostatitisInflammation of the prostate gland that begins suddenly and gets worse quickly. It is caused by a bacterial...
acute leukemiaA rapidly progressing cancer that starts in blood-forming tissue such as the bone marrow, and causes large...
acute lymphoblastic leukemiaA type of leukemia (blood cancer) that comes on quickly and is fast growing. In acute lymphoblastic leukemia...
acute lymphocytic leukemiaA type of leukemia (blood cancer) that comes on quickly and is fast growing. In acute lymphocytic leukemia...
acute myelogenous leukemiaA fast-growing cancer in which too many myeloblasts (a type of immature white blood cell) are found in the...
acute myeloid leukemiaA fast-growing cancer in which too many myeloblasts (a type of immature white blood cell) are found in the...
acute myeloid leukemia with myelodysplasia-related changesA type of acute myeloid leukemia in which at least 20% of a patient’s blood or bone marrow is myeloblasts...
acute nonlymphocytic leukemiaA fast-growing cancer in which too many myeloblasts (a type of immature white blood cell) are found in the...
acute painPain that comes on quickly, can be severe, but lasts a relatively short time.
acute paronychiaAn infection of the soft tissue around a fingernail or toenail that begins suddenly and can get worse...
acute promyelocytic leukemiaAn aggressive (fast-growing) type of acute myeloid leukemia in which there are too many immature...
acute radiation sicknessSerious illness caused by being exposed to high doses of certain types of radiation, usually over a short...
acute radiation syndromeSerious illness caused by being exposed to high doses of certain types of radiation, usually over a short...
acyclic nucleoside phosphonate prodrug ABI-1968A prodrug of an acyclic nucleoside phosphonate, with potential anti-viral and antineoplastic activities. Upon...
acyclovirA substance used to prevent or treat cytomegalovirus and herpes simplex infections that may occur when the...
Acyclovir SodiumThe sodium salt form of acyclovir, a synthetic analog of the purine nucleoside, guanosine, with potent...
acylfulvene-derived prodrug LP-184A tumor-site activated acylfulvene-derived prodrug and alkylating agent, with potential antineoplastic...
AD 32A drug used to treat bladder carcinoma in situ that did not get better after treatment with bacillus...
Ad5 [E1-, E2b-]-HER2/Neu vaccine ETBX-021A cancer vaccine composed of a genetically engineered, replication-defective oncolytic adenovirus serotype 5...
Ad5-CMV-NISA recombinant type 5 adenovirus (Ad5), encoding the gene for the human sodium-iodide symporter (NIS) linked...
Ad5-encoding IFNg SP-002A replication deficient adenovirus type 5 (Ad5) vector encoding for the cytokine human interferon gamma...
Ad5F35-LMP1/LMP2-transduced autologous dendritic cellsAutologous dendritic cells (DCs) transduced with the replication-deficient adenoviral vector Ad5F53 encoding...
Ad5-SGE-REIC/Dkk-3 MTG-201A replication incompetent adenoviral vector type 5 (Ad5) encoding the tumor suppressor gene dickkopf-3 (DKK3...
Ad5.SSTR/TK.RGDAn RGD-4C-modified, infectivity-enhanced, bicistronic type 5 adenovirus expressing herpes simplex virus...
Ad5-survivin-transduced autologous dendritic cell vaccineA cell-based cancer vaccine containing autologous dendritic cells (DCs) that are transduced with a...
Ad5-yCD/mutTK(SR39)rep-ADPA second generation, replication-competent adenovirus type 5 containing a yeast cytosine...
Ad5-yCD/mutTKSR39rep-hIL12A replication-competent oncolytic adenovirus encoding the murine pro-inflammatory cytokine interleukin-12...
adagloxad simoleninA carbohydrate-based immunostimulant comprised of the Globo H hexasaccharide 1 (Globo H) epitope linked to...
adagrasibA drug used alone or with cetuximab to treat adults with colorectal cancer or non-small cell lung cancer that...
adakitugA human monoclonal antibody against the pro-inflammatory mediator interleukin-8 (IL-8; CXCL8), with potential...
adalimumabA recombinant, human IgG1 monoclonal antibody directed against tumor necrosis factor-alpha (TNF-alpha), with...
adapaleneA topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is...
adaptive immunityA type of immunity that develops when a person’s immune system responds to a foreign substance or...
ADA-SCIDA rare, inherited disorder in which the immune system is damaged, causing a person to have a complete lack of...
adavosertibA small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity...
ADCA substance made up of a monoclonal antibody chemically linked to a drug. The monoclonal antibody binds to...
AdC68 Expressing PSA/PSMA/PSCA Vaccine PF-06755992A prime cancer vaccine comprised of a genetically engineered, replication-deficient chimpanzee adenovirus...
ADCCA type of immune reaction in which a target cell or microbe is coated with antibodies and killed by certain...
AdcetrisA drug used alone or with other drugs to treat adults with certain types of classic Hodgkin lymphoma...
AdderallA combination of drugs used as a treatment for attention deficit hyperactivity disorder (ADHD) and narcolepsy...
addictionAn uncontrollable craving, seeking, and use of a substance, such as a drug or alcohol.
Addison diseaseA rare disorder in which the adrenal glands do not make enough of certain hormones. Symptoms include weight...
ADEAn abbreviation for a chemotherapy combination used to treat childhood acute myeloid leukemia (AML). It...
ADE regimenAn abbreviation for a chemotherapy combination used to treat childhood acute myeloid leukemia (AML). It...
adebrelimabAn immunoglobulin G4 (IgG4), humanized monoclonal antibody directed against the immunosuppressive ligand...
adecatumumabA recombinant human IgG1 monoclonal antibody (MoAb) directed against the tumor associated antigen (TAA)...
adefovir dipivoxilA dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with...
adenineA chemical compound that is used to make one of the building blocks of DNA and RNA. It is also a part of many...
adeno-associated virus encoding anti-CD19/anti-CD3 bispecific diabody VNX-101An off-the-shelf preparation of adeno-associated virus (AAV) encoding the anti-CD19/anti-CD3 bispecific...
adenocarcinomaCancer that forms in the glandular tissue, which lines certain internal organs and makes and releases...
adenocarcinoma in situA condition in which abnormal cells are found in the glandular tissue, which lines certain internal organs...
adenoid cystic carcinomaA rare type of cancer that begins in cells that line certain internal organs and make and release substances...
adenomaA tumor that is not cancer. It starts in gland-like cells of the epithelial tissue (thin layer of tissue that...
adenopathyLarge or swollen lymph glands.
adenosarcomaA tumor that is a mixture of an adenoma (a tumor that starts in the gland-like cells of epithelial tissue)...
adenosine A2A receptor antagonist AZD4635An orally bioavailable antagonist of the adenosine A2A receptor (A2AR; ADORA2A), with potential...
adenosine A2A receptor antagonist CS3005An orally bioavailable immune checkpoint inhibitor and antagonist of the adenosine A2A receptor (A2AR...
adenosine A2A receptor antagonist DZD2269An immune checkpoint inhibitor and antagonist of the adenosine A2A receptor (A2AR; ADORA2A), with potential...
adenosine A2A receptor antagonist ILB2109An orally bioavailable immune checkpoint inhibitor and antagonist of the adenosine A2A receptor (A2AR...
adenosine A2A receptor antagonist JNJ-86974680An immune checkpoint inhibitor and antagonist of the adenosine A2A receptor (A2AR; ADORA2A), with potential...
adenosine A2A receptor antagonist NIR178An orally bioavailable immune checkpoint inhibitor and antagonist of the adenosine A2A receptor (A2AR...
adenosine A2A receptor antagonist PBF-509An orally bioavailable adenosine A2A receptor (A2AR) antagonist, with potential antineoplastic activity. Upon...
adenosine A2A receptor antagonist TT-10An immune checkpoint inhibitor and antagonist of the adenosine A2A receptor (A2AR; ADORA2A), with potential...
adenosine A2A receptor antagonist/phosphodiesterase 10A PBF-999An orally bioavailable inhibitor of both the adenosine A2A receptor (A2AR; ADORA2A) and phosphodiesterase 10A...
adenosine A2B receptor antagonist PBF-1129An orally bioavailable antagonist of the immunomodulatory checkpoint molecule adenosine A2B receptor (A2BR...
adenosine A2B receptor antagonist TT-4An orally bioavailable antagonist of the immunomodulatory checkpoint molecule adenosine A2B receptor (A2BR...
adenosine A2B receptor antagonist TT-702An orally bioavailable prodrug and selective antagonist of the immunomodulatory checkpoint molecule adenosine...
adenosine deaminase-deficient severe combined immunodeficiencyA rare, inherited disorder in which the immune system is damaged, causing a person to have a complete lack of...
adenosine receptor A2A/A2B antagonist M1069An orally bioavailable antagonist of both the immunomodulatory checkpoint molecules adenosine A2A receptor...
adenosine triphosphateA substance present in all living cells that provides energy for many metabolic processes and is involved in...
adenosisA disease or abnormal change in a gland. Breast adenosis is a benign condition in which the lobules are...
adenosquamous carcinomaA type of cancer that contains two types of cells: squamous cells (thin, flat cells that line certain organs)...
adenovector encoding MDA7A nonreplicating adenoviral vector (adenovector) encoding the melanoma differentiation-associated 7 gene...
adenovector-transduced AP1903-inducible MyD88/CD40-expressing autologous PSMA-specific prostate cancer vaccine BPX-201A genetically-modified, dendritic cell (DC)-based vaccine in which the autologous cells are transduced with...
adenoviral brachyury vaccine ETBX-051A therapeutic cancer vaccine composed of a replication-defective, serotype 5 adenovirus (Ad5) with the viral...
adenoviral cancer vaccine PF-06936308A cancer vaccine composed of a replication-defective E1-deleted adenovirus vector based on chimpanzee...
adenoviral MUC1 vaccine ETBX-061A therapeutic cancer vaccine composed of a replication-defective, serotype 5 adenovirus (Ad5) with the viral...
adenoviral PSA vaccine ETBX-071A cancer vaccine composed of a genetically engineered, replication-deficient adenovirus carrying the gene...
adenoviral tumor-specific neoantigen priming vaccine GAd-209-FSPAn off-the-shelf neoantigen priming vaccine comprised of a great ape adenovirus (GAd) encoding tumor-specific...
adenoviral tumor-specific neoantigen priming vaccine GRT-C901A personalized cancer vaccine comprised of a chimpanzee adenovirus vector (ChAdV) encoding twenty...
adenoviral vector Ad5-CEA(6D) vaccineA replication-defective, E1- and E2b-deleted oncolytic adenoviral serotype 5 (Ad5) encoding an epitope of...
adenoviral vector encoding VEGF-C LX-1101A genetically engineered, replication-deficient adenovirus carrying the gene encoding for the human vascular...
adenoviral-transduced hIL-12-expressing autologous dendritic cells INXN-3001 plus activator ligand INXN-1001Autologous dendritic cells tranduced with a replication incompetent adenovirus encoding human...
adenovirusA member of a family of viruses that can cause infections in the respiratory tract, eye, and gastrointestinal...
adenovirus 5 CEA/MUC1/brachyury vaccine Tri-Ad5A combination of three therapeutic cancer vaccines each containing a replication-defective, oncolytic...
adenovirus 5-CD40 ligandAn adenovirus vector engineered to produce CD40 ligand. For use as a possible gene therapy agent. May induce...
adenovirus 5/F35-human guanylyl cyclase C-PADREA recombinant adenoviral serotype 5 (Ad5) in which the Ad5-based vector fiber is replaced by the fiber from...
adenovirus 5-human guanylyl cyclase C-PADRE vaccineA replication-defective, recombinant adenoviral serotype 5 (Ad5) encoding human guanylyl cyclase C (hGCC) and...
adenovirus B7-1A gene-viral vector complex comprised of an adenovirus vector and B7-1 gene targeting the CD80 antigen...
adenovirus encoding human aquaporin-1A replication-deficient, recombinant adenovirus encoding human aquaporin-1 with potential membrane water...
adenovirus encoding rat Her-2/neuA replication-defective oncolytic adenovirus, encoding rat Her-2/neu (ErbB-2), with potential antineoplastic...
adenovirus encoding recombinant human endostatinA replication-defective, recombinant oncolytic adenovirus encoding human endostatin with potential...
adenovirus encoding tyrosinase/MART-1/MAGEA6-transduced autologous dendritic cell vaccineA cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant...
adenovirus expressing mutant HPV E6/E7A cancer vaccine comprised of a genetically engineered, replication-deficient adenovirus encoding inactive...
adenovirus HER2-transduced autologous dendritic cell vaccineA cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a...
adenovirus RSV-TKA gene viral vector complex comprised of a replication-defective adenovirus and a herpes simplex virus...
adenovirus serotype 26-expressing HPV16 vaccine JNJ-63682918A prime cancer vaccine comprised of a genetically engineered, replication-deficient adenovirus serotype 26...
adenovirus serotype 26-expressing HPV18 vaccine JNJ-63682931A prime cancer vaccine comprised of a genetically engineered, replication-deficient adenovirus serotype 26...
adenovirus vectorA form of a common virus called adenovirus that is used to deliver genetic material, such as a new gene or a...
adenovirus/cytomegalovirus/Epstein-Barr virus-specific allogeneic cytotoxic T lymphocytesAllogeneic tri-viral specific, adenovirus, cytomegalovirus and Epstein-Barr virus (Adv, CMV and EBV or ACE)...
adenovirus-encoding E.coli PNPA replication-incompetent adenovirus encoding E. coli purine nucleoside phosphorylase (Ad/PNP) used as a...
adenovirus-expressing TLR5/TLR5 agonist nanoformulation M-VM3A nanoparticle-based formulation containing a recombinant non-replicating adenovirus (Ad) encoding toll-like...
adenovirus-mediated human interleukin-12A replication-incompetent adenovirus encoding human pro-inflammatory cytokine interleukin-12 (IL-12)...
adenovirus-mediated human interleukin-12 INXN-2001 plus activator ligand INXN-1001A replication incompetent adenovirus encoding the human pro-inflammatory cytokine interleukin-12 (IL-12)...
adenovirus-p53 transduced dendritic cell vaccineA cancer vaccine consisting of autologous dendritic cells (DCs) transduced with a recombinant adenovirus...
adenovirus-PSA prostate cancer vaccineA cancer vaccine composed of a genetically engineered, replication-deficient type 5 adenovirus carrying the...
AdGMCAIX-transduced autologous dendritic cellsAutologous dendritic cells (DCs) transduced with a recombinant, replication-defective adenoviral vector...
ADHA benign (not cancer) condition in which there are more cells than normal in the lining of breast ducts and...
ADH-1A small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic...
Ad-hCMV-Flt3LA human serotype 5, replication-defective, first generation adenoviral vector, with the viral E1a and E3...
Ad-hCMV-TKA human serotype 5, replication-defective, first generation adenoviral vector, with the viral E1a and E3...
ADI-PEG 20A substance being studied in the treatment of melanoma, liver cancer, and other types of cancer. It breaks...
adipokineOne of a large group of molecules that is made by fat cells in the body. Adipokines circulate in the blood...
adipose-derived expanded mesenchymal stem cells SCM-010A preparation of human adipose-derived mesenchymal stem cells (MSCs), that can potentially be used for...
adipose-derived regenerative cellsA population of cells derived from adipose tissue with stem cell and wound repair activities. Adipose-derived...
adipose-derived stromal vascular fraction cellsA population of stromal vascular fraction (SVF) cells derived from autologous adipose tissue, with potential...
Ad-ISF35A replication-defective adenovirus vector (Ad-ISF35), which encodes a membrane-stabilized, chimeric...
adjunct agentIn cancer therapy, a drug or substance used in addition to the primary therapy.
adjunct therapyAnother treatment used together with the primary treatment. Its purpose is to assist the primary treatment...
adjunctive therapyAnother treatment used together with the primary treatment. Its purpose is to assist the primary treatment...
adjustment disorderA condition in which a person responds to a stressful event (such as an illness, job loss, or divorce) with...
adjuvant chemotherapyAnticancer drugs given after the primary (or first) treatment to kill any cancer cells that remain in the...
adjuvant therapyAdditional cancer treatment given after the primary treatment to lower the risk that the cancer will come...
ADLActivities of daily living. The tasks of everyday life. Basic ADLs include eating, dressing, getting into or...
administrationIn medicine, the act of giving a treatment, such as a drug, to a patient. It can also refer to the way it is...
adnexal massA lump in tissue near the uterus, usually in the ovary or fallopian tube. Adnexal masses include ovarian...
adolescentA young person who has begun puberty but has not yet become an adult. During adolescence, a child experiences...
adoptive cell therapyA type of immunotherapy in which T cells (a type of immune cell) are given to a patient to help the body...
adoptive cell therapy agentA preparation of allogeneic or autologous cells that is meant to be administered to a patient and may have an...
adoptive cell transferA type of immunotherapy in which T cells (a type of immune cell) are given to a patient to help the body...
ado-trastuzumab emtansineA drug used to treat certain patients with HER2-positive breast cancer that has already been treated with...
adozelesinAn alkylating agent that bind to the DNA minor groove in a sequence-specific manner and form covalent adducts...
adrenal cancerCancer that forms in the tissues of the adrenal glands (two glands located just above the kidneys). The...
adrenal cortexThe outer part of the adrenal gland (a small organ on top of each kidney). The adrenal cortex makes androgen...
adrenal glandOne of a pair of small, triangle-shaped glands on top of each kidney. Each adrenal gland has two parts: the...
adrenal insufficiencyA rare disorder in which the adrenal glands do not make enough of certain hormones. Symptoms include weight...
adrenal medullaThe inner part of the adrenal gland (a small organ on top of each kidney). The adrenal medulla makes...
adrenalectomySurgery to remove one or both adrenal glands (a small organ on top of each kidney).
adrenalineA hormone and neurotransmitter. Also called epinephrine.
adrenocorticalHaving to do with or made by the outer layer of the adrenal gland, which produces steroid hormones. There is...
adrenocortical cancerA rare cancer that forms in the outer layer of tissue of the adrenal gland (a small organ on top of each...
adrenocortical carcinomaA rare cancer that forms in the outer layer of tissue of the adrenal gland (a small organ on top of each...
adrenocorticotropic hormoneA hormone made in the pituitary gland. Adrenocorticotropic hormone acts on the outer part of the adrenal...
adrenocorticotropic-secreting tumorA rare tumor that makes the hormone adrenocorticotropin (ACTH), which causes the adrenal glands to make too...
AdreViewA drug containing a form of radioactive iodine called I 123 that is used to find certain types of tumors...
AdriamycinA drug that comes from the bacterium Streptomyces peucetius and is used alone or with other drugs to treat...
Ad-RTS-hIL-12An inducible adenoviral vector encoding human pro-inflammatory cytokine interleukin-12 (IL-12; IL12), which...
AdRTVP-1-transduced prostate cancer cell-based vaccineA cell-based vaccine comprised of prostate cancer cells transduced with an adenoviral vector encoding human...
Ad-sig-hMUC-1/ecdCD40L vaccineA cancer vaccine consisting of a recombinant adenoviral vector encoding the tumor-associated antigen (TAA)...
AdstiladrinA drug used to treat adults with a certain type of high-risk bladder cancer that has not invaded the muscle...
adult progeriaA rare, inherited disorder marked by rapid aging that begins in early adolescence or young adulthood and an...
adult ricketsA condition in adults in which bones become soft and deformed because they don’t have enough calcium and...
adult T-cell leukemia/lymphomaAn aggressive (fast-growing) type of T-cell non-Hodgkin lymphoma caused by the human T-cell leukemia virus...
adulterantA substance added to a product but not listed as an ingredient, or a substance that ends up in a product by...
adult-type fibrosarcomaA type of cancer that forms in fibrous (connective) tissue. It can occur anywhere in the body. Adult-type...
advance directiveA legal document that states a person’s wishes about receiving medical care if that person is no longer able...
advanced cancerA term that is often used to describe cancer that is unlikely to be cured. However, some advanced cancers can...
advanced practice nurseA registered nurse who has additional education and training in how to diagnose and treat disease. Advanced...
advanced practice providerA medical professional who is not a doctor but has special training and is licensed to diagnose, treat, and...
adverse effectAn undesired effect of a drug or other type of treatment, such as surgery. Adverse effects can range from...
adverse eventAn undesired effect of a drug or other type of treatment, such as surgery. Adverse events can range from mild...
adverse reactionAn undesired effect of a drug or other type of treatment, such as surgery. Adverse reactions can range from...
AdvilA drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that...
AE37 peptide/GM-CSF vaccineA vaccine containing HER2/Neu-derived epitope (amino acids 776-790) linked to li-Key peptide (li-Key/HER2/neu...
AE-941A substance made from shark cartilage that is being studied for its ability to prevent the growth of new...
AEE788A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called...
AEG35156A substance being studied in the treatment of cancer. AEG35156 may kill cancer cells by blocking the...
aeneic multi-virus-specific T cells ALVR106A preparation of off-the-shelf (OTS), donor-derived T lymphocytes that are specifically reactive towards four...
aerobicIn biochemistry, reactions that need oxygen to happen or happen when oxygen is present.
aerobic exercisePhysical activity that increases the heart rate and the body’s use of oxygen. It helps improve a person’s...
aerobic metabolismA chemical process in which oxygen is used to make energy from carbohydrates (sugars). Also called aerobic...
aerobic respirationA chemical process in which oxygen is used to make energy from carbohydrates (sugars). Also called aerobic...
aerodigestive tractThe combined organs and tissues of the respiratory tract and the upper part of the digestive tract (including...
aerosol gemcitabineAn aerosol inhalation formulation containing gemcitabine (GCB), a broad-spectrum antimetabolite and...
aerosol sargramostimAn aerosol inhalation formulation containing a yeast-derived glycosylated recombinant form of human...
aerosolizeIn medicine, to turn a liquid drug into a fine mist that can be inhaled.
aerosolized aldesleukinAn aerosol formulation of aldesleukin, a recombinant form of interleukin-2 (IL-2), with potential...
aerosolized liposomal rubitecanAn aerosolized liposomal preparation of rubitecan, a water-insoluble derivative of camptothecin with...
aesthetic flat closureA type of surgery that is done to rebuild the shape of the chest wall after one or both breasts are removed...
afamelanotideA synthetic peptide analogue of the naturally occurring alpha-melanocyte stimulating hormone (a-MSH) with...
afamitresgene autoleucelA treatment used for adults with synovial sarcoma that has the MAGE-A4 antigen and has spread to other parts...
AFAPA rare, inherited disorder in which multiple polyps (abnormal growths) form on the inner walls of the colon...
afatinib dimaleateA drug used to treat certain types of non-small cell lung cancer that have spread to other parts of the body...
afeletecan hydrochlorideThe hydrochloride salt form of afeletecan, a water-soluble camptothecin derivative conjugated to a...
affected individualIn genetics, a term used to describe a person who has a certain genetic trait or who shows the signs and...
affinityIn chemistry and biology, the strength of the attaction between two substances, such as two chemicals, or an...
affinity reagentIn chemistry and biology, a compound that binds specific substances, such as proteins or nucleic acids. Many...
afibAn irregular heartbeat that occurs when the electrical signals in the atria (the two upper chambers of the...
afimoxifeneA tamoxifen metabolite with both estrogenic and anti-estrogenic effects. Afimoxifene has a higher affinity...
AfinitorA drug that contains the active ingredient everolimus and is used alone or with other drugs to treat certain...
Afinitor DisperzA drug that contains the active ingredient everolimus and is used to treat a type of benign brain tumor...
aflatoxinA harmful substance made by certain types of mold (Aspergillus flavus and Aspergillus parasiticus) that is...
AFLDA condition in which fat builds up in the liver of people who drink large amounts of alcohol. AFLD can be...
AFPA protein normally produced by a fetus. AFP levels are usually undetectable in the blood of healthy adult men...
AFP gene hepatocellular carcinoma vaccineA cancer vaccine composed of naked plasmid DNA of the gene for the tumor-associated antigen alpha-fetoprotein...
AFP464A substance being studied in the treatment of cancer. AFP464 kills cancer cells or stops them from dividing...
afuresertibAn orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential...
AG-013736A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called...
AG014699A drug used to treat adults with certain types of prostate cancer or ovarian epithelial, fallopian tube, or...
AG2037A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
AG3340A substance that is being studied in the treatment of cancer. It is a matrix metalloproteinase inhibitor and...
AG337A substance that is being studied in the treatment of liver cancer. It belongs to the family of drugs called...
aganglionic megacolonA condition in which certain nerve cells are missing from the muscle layers of part of the large intestine...
Agaricus blazei Murill extractA dietary supplement containing an extract of the Basidiomycete fungus Agaricus blazei Murill with potential...
agatolimod sodiumThe tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential...
AGCA finding of abnormal cells in a Pap test. The glandular cells come from the inner part of the cervix or the...
age-adjusted rateA statistical measure that allows groups of people to be compared in a way that the age distribution...
agent studyIn cancer prevention, a clinical trial that studies whether taking certain medicines, vitamins, minerals, or...
agerafenib1. An orally bioavailable selective multikinase inhibitor of mutant forms, fusions and rearrangements...
age-related macular degenerationA condition in which there is a slow breakdown of cells in the center of the retina (the light-sensitive...
agglutininA substance that makes particles (such as bacteria or cells) stick together to form a clump or a mass.
aggravating factorSomething that makes a condition worse. For example, tobacco smoke is an aggravating factor for asthma.
aggressiveIn medicine, describes a tumor or disease that forms, grows, or spreads quickly. It may also describe...
aggressive fibromatosisA rare type of soft tissue tumor that forms in fibrous connective tissue of the body, usually in the abdomen...
aggressive lymphomaA type of lymphoma that grows and spreads quickly and has severe symptoms. Also called high-grade lymphoma...
aggressive systemic mastocytosisA rare condition in which too many mast cells (a type of white blood cell) build up in certain tissues and...
agitationA condition in which a person is unable to relax and be still. The person may be very tense and irritable...
aglatimagene besadenovecAn adenoviral vector engineered to express the herpes simplex virus thymidine kinase (HSV-tk) gene, which...
agnogenic myeloid metaplasiaA progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in...
agonistA drug or substance that binds to a receptor inside a cell or on its surface and causes the same action as...
agonistic anti-OX40 monoclonal antibody INCAGN01949An agonistic human immunoglobulin G1 (IgG1) monoclonal antibody that recognizes the co-stimulatory receptor...
agonistic anti-OX40 monoclonal antibody MEDI6469An agonistic monoclonal antibody against the co-stimulatory receptor OX40 (CD134), with potential...
agoraphobiaAn intense fear of being in open places or in situations where it may be hard to escape, or where help may...
agranulocyteA type of white blood cell. Monocytes and lymphocytes are agranulocytes.
agranulocytosisA serious condition that occurs when there is an extremely low number of granulocytes (a type of white blood...
AGUSA term that has been used to describe abnormal cells that come from glands in the walls of the cervix (the...
AHAOne of a group of substances that are found in several types of fruit and in milk. They are used in skin care...
AhR inhibitor DA-4505An orally bioavailable small molecule inhibitor of the aryl hydrocarbon receptor (AhR; class E basic...
AIThe ability of a computer to perform functions that are usually thought of as intelligent human behavior...
AI drugA drug that blocks the activity of an enzyme called aromatase, which the body uses to make estrogen in the...
Aicardi syndromeA rare, genetic disorder marked by a lack of tissue connecting the left and right halves of the brain...
AIDSA disease caused by the human immunodeficiency virus (HIV). People with AIDS are at an increased risk for...
AIDS-defining cancerA type of cancer that a person infected with human immunodeficiency virus (HIV) is at high risk of...
AIDS-related cancerA type of cancer that is more likely to occur in people who are infected with the human immunodeficiency...
AIE regimenA regimen consisting of cytarabine (Ara-C), idarubicin and etoposide, used as an induction treatment for...
AIM2(-1)/HT001(-1)/TAF1B(-1) frameshift peptide vaccineA cancer vaccine containing the three frame shift peptides (FSP) AIM2(-1), HT001(-1) and TAF1B(-1), with...
AISA condition in which abnormal cells are found in the glandular tissue, which lines certain internal organs...
AJCC staging systemA system to describe the amount and spread of cancer in a patient’s body, using TNM. T describes the size of...
AK 3012A proprietary topical formulation. Upon subcutaneous administration, the active ingredient in AK 3012 may...
AkeegaA combination of niraparib tosylate monohydrate and abiraterone acetate used with prednisone to treat adults...
Akkermansia muciniphila probioticAn orally bioavailable, probiotic supplement containing Akkermansia muciniphila (A. muciniphila), a naturally...
AKR1C3-activated prodrug AST-3424A small-molecule nitro-benzene, aldo-keto reductase 1C3 (AKR1C3)-activated prodrug of...
AktA group of enzymes involved in several processes related to cell growth and survival. Akt enzymes help to...
AKT 1/2 inhibitor BAY1125976An orally bioavailable inhibitor of the serine/threonine protein kinase AKT (protein kinase B) isoforms 1 and...
AKT inhibitorAny agent that inhibits protein kinase B (AKT).
Akt inhibitor GSK2141795An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential...
Akt inhibitor LY2780301An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential...
Akt inhibitor MK2206An orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B)...
Akt inhibitor NTQ1062An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B), with...
Akt inhibitor SR13668An orally bioavailable indole-3-carbinol (I3C) analogue inhibitor of the serine/threonine protein kinase Akt...
AKT-1 antisense oligonucleotide WGI-0301A lipid nanoparticle preparation of archexin, a 20-mer antisense (AS) oligodeoxynucleotide (ODN) against the...
AKT1 E17K inhibitor ALTA2618An orally bioavailable covalent inhibitor of the serine/threonine protein kinase AKT (protein kinase B; v-akt...
Akt-1/2 inhibitor-treated tumor infiltrating lymphocytesAutologous tumor infiltrating lymphocytes (TILs) harvested directly from the infiltrate of a patient's tumor...
AKT/RSK/S6K inhibitor TAS0612An orally bioavailable inhibitor of the serine/threonine kinases AKT (protein kinase B), 90S ribosome S6...
AkynzeoA combination of two drugs used with dexamethasone in adults to prevent nausea and vomiting caused by...
alacizumab pegolA pegylated, cross-linked, humanized divalent-Fab' antibody fragment directed against vascular endothelial...
Alagille syndromeA rare disorder in which there are defects in the small tubes that carry bile (fluid that helps digest fat)...
alanine aminopeptidaseAn enzyme that is normally found in healthy kidneys. It may be found at high levels in the urine when there...
alanine transferaseAn enzyme found in the liver and other tissues. A high level of alanine transferase released into the blood...
alanosineA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
alanylglutamineA nutritional supplement containing a stable, water-soluble dipeptide comprised of the amino acids...
albendazoleA broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the...
albinismA group of genetic conditions marked by little or none of the pigment melanin in the skin, hair, and/or eyes...
albuminA type of protein found in blood, egg white, milk, and other substances.
Albumin-binding Cisplatin Prodrug BTP-114A proprietary, albumin-binding platinum (Pt)-based complex containing a prodrug form of the platinum compound...
albuterolA racemic mixture of the r-isomer levalbuterol and s-albuterol, a short-acting sympathomimetic agent with...
albuterol sulfateThe sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol...
ALC1 inhibitor EIS-12656An orally bioavailable allosteric inhibitor of the chromatin remodeling enzyme...
ALCARA form of the natural substance carnitine that is being studied as a way to prevent tissue damage caused by...
ALCLAn aggressive (fast-growing) type of non-Hodgkin lymphoma that is usually of the T-cell type. The cancer...
alcoholA chemical substance found in drinks such as beer, wine, and liquor. It is also found in some medicines...
alcohol ablationAn injection of ethanol (alcohol) through the skin directly into a tumor to kill cancer cells. Ultrasound or...
alcohol dependenceA chronic disease in which a person craves drinks that contain alcohol and is unable to control his or her...
alcohol-free hypoallergenic barrier film solutionAn alcohol-free, hypoallergenic, polymeric-cyanoacrylate-based solution that provides a barrier film, with...
alcoholic fatty liver diseaseA condition in which fat builds up in the liver of people who drink large amounts of alcohol. Alcoholic fatty...
alcoholismA chronic disease in which a person craves drinks that contain alcohol and is unable to control his or her...
AldaraA drug that contains the active ingredient imiquimod and is used to treat certain skin conditions. Aldara is...
aldastotugA humanized monoclonal antibody targeting the immune checkpoint molecule sialic acid-binding immunoglobulin...
aldehydeA type of chemical substance made from alcohol. Aldehydes are found in essential oils (scented liquid taken...
aldesleukinA drug used to treat adults with melanoma or renal cell carcinoma (a type of kidney cancer) that has spread...
ALDH inhibitor NYH817G and mitochondrial complex 1 inhibitor NYH100PAn orally bioavailable combination agent composed of the aldehyde dehydrogenase (ALDH) inhibitor NYH817G and...
ALDH1/3 inhibitor ABD-3001A suicidal inhibitor of aldehyde dehydrogenases 1 (ALDH1) and 3 (ALDH3), with potential antineoplastic...
aldosteroneA steroid hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps control the...
aldoxorubicinA 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH)...
Aldrich syndromeAn inherited immune disorder that occurs in young boys. It causes eczema (a type of skin inflammation), a...
AlecensaA drug used to treat adults with certain types of non-small cell lung cancer that are ALK positive. It used...
alectinibA drug used to treat adults with certain types of non-small cell lung cancer that are ALK positive. It used...
alefaceptA drug that is used to treat certain skin conditions and is being studied in the treatment of cutaneous...
alemtuzumabA drug used to treat B-cell chronic lymphocytic leukemia. It is also being studied in the treatment of other...
alendronate sodiumA drug used to treat certain bone conditions, such as osteoporosis and Paget disease of the bone. It is also...
alfentanil hydrochlorideThe hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia...
alflutinib mesylateThe mesylate salt form of alflutinib, an orally available selective inhibitor of the epidermal growth factor...
alfuzosin hydrochlorideThe hydrochloride salt of alfuzosin, a quinazoline compound with smooth muscle-relaxing activity. Alfuzosin...
algenpantucel-LA cancer vaccine comprised of irradiated allogeneic pancreatic cancer cells transfected to express murine...
ALHA benign (not cancer) condition in which there are more cells than normal in the breast lobules and the cells...
alimentary tractThe organs that food and liquids travel through when they are swallowed, digested, absorbed, and leave the...
AlimtaA drug used alone or with other drugs to treat certain types of non-small cell lung cancer and malignant...
alintegimodAn orally bioavailable, allosteric, small molecule activator of integrin cell adhesion receptors very late...
alirocumabA human immunoglobulin G1 (IgG1) monoclonal antibody directed against human proprotein convertase...
alisertibA second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine...
alisertib sodiumA substance that binds to a protein called Aurora A kinase and blocks its activity. Aurora A kinase plays an...
alitretinoinAn orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive...
alizaprideA substituted benzamide that acts as a dopamine receptor antagonist with antiemetic properties.
ALK geneA gene that makes a protein that is involved in cell growth. Mutated (changed) forms of the ALK gene and...
ALK inhibitorA substance that blocks the activity of a protein called anaplastic lymphoma kinase (ALK), which helps...

3,095 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.