Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: P (1,454)

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p21 gene activator saRNA RAG-01A small activating RNA (saRNA) targeting the tumor suppressor gene p21, with potential antineoplastic...
P2RX3 antagonist BAY 1817080An orally bioavailable antagonist of the purinergic receptor P2X ligand-gated ion channel 3 (P2RX3), which...
P30 Cancer Center Support GrantFunds awarded to certain U.S. institutions by the National Cancer Institute (NCI) for them to become cancer...
p300/CBP bromodomain inhibitor CCS1477An orally bioavailable, small molecule inhibitor of the highly conserved bromodomains of the histone...
P30-linked EphA2/CMV pp65/survivin peptide vaccine P30-EPSA peptide vaccine comprised of three immunogenic tetanus toxoid epitope P30-linked tumor-associated antigen...
P-32A radioactive form of the element phosphorus used in the treatment of cancer.
p38 MAPK inhibitor LY2228820 dimesylateThe dimesylate salt form of LY2228820, a tri-substituted imidazole derivative and orally available, p38...
p38 MAPK inhibitor LY3007113An orally active p38 mitogen-activated protein kinase (MAPK) inhibitor with potential immunomodulating...
p53 geneA gene that makes a protein that is found inside the nucleus of cells and plays a key role in controlling...
p53 mutant reactivator APR-548An analog of eprenetapopt and an orally bioavailable, small molecule prodrug and reactivator of p53 mutants...
p53 peptide vaccineA peptide-based cancer vaccine composed of amino acids 264 to 272 of the wild-type protein encoded by the P53...
p53 synthetic long peptide (70-251) vaccineA peptide vaccine consisting of 10 synthetic long peptides (SLPs), 25-30 amino acids in size and derived from...
p53 Y220C mutant reactivator PC14586An orally bioavailable, small molecule reactivator of the p53 Y220C mutant, with potential antineoplastic...
p53 Y220C reactivator JAB-30355An orally bioavailable reactivator of the tumor suppressor protein p53 mutation TP53 Y220C, with potential...
p53/HDM2 interaction inhibitor CGM097An orally bioavailable HDM2 (human homolog of double minute 2) antagonist with potential antineoplastic...
p53-HDM2 protein-protein interaction inhibitor MI-773An orally available spiro-oxindole HDM2 (human double minute 2) antagonist with potential antineoplastic...
p70S6K inhibitor LY2584702An orally available inhibitor of p70S6K signaling, with potential antineoplastic activity. p70S6K inhibitor...
p70S6K/Akt inhibitor M-2698An orally available inhibitor of the serine/threonine protein kinases ribosomal protein S6 Kinase (p70S6K)...
p97 inhibitor CB-5083An orally bioavailable inhibitor of valosin-containing protein (VCP) p97, with potential antineoplastic...
p97 Inhibitor CB-5339An orally bioavailable, selective, second-generation inhibitor of valosin-containing protein (VCP)/p97, with...
p97 inhibitor CB-5339 tosylateThe tosylate salt of CB-5339, an orally bioavailable, selective, second-generation inhibitor of...
PAA health professional who is licensed to do certain medical procedures under the guidance of a doctor. A PA...
PA-1-STK ovarian carcinoma vaccineA cell-based cancer vaccine with potential antineoplastic activity. PA-1-STK ovarian carcinoma vaccine is...
PABAA nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy...
pacanalotamabA short half-life bispecific T-cell engager (BiTE) antibody composed of two single-chain variable fragments...
pacemakerAn electronic device that is implanted in the body to monitor heart rate and rhythm. It gives the heart...
Pacific valerianA plant whose roots are used as a sedative and to treat certain medical conditions. It is being studied as a...
pack yearA way to measure the amount a person has smoked over a long period of time. It is calculated by multiplying...
paclitaxelA drug used alone or with other drugs to treat AIDS-related Kaposi sarcoma, advanced ovarian cancer, and...
paclitaxel albumin-stabilized nanoparticle formulationA form of the anticancer drug paclitaxel that is used alone or with other drugs to treat certain types of...
paclitaxel and hyaluronic acidA water soluble, muco-adhesive co-formulation composed of the natural taxane paclitaxel conjugated to the...
paclitaxel injection concentrate for nanodispersionA nanoparticle-based injectable concentrate containing the water-insoluble taxane paclitaxel, with potential...
paclitaxel liposomeA form of the anticancer drug paclitaxel that is contained in very tiny, fat-like particles. It may have...
paclitaxel poliglumexA form of the anticancer drug paclitaxel combined with a protein called poliglumex that may have fewer side...
paclitaxel polyglutamateA form of the anticancer drug paclitaxel combined with a protein called poliglumex that may have fewer side...
paclitaxel polymeric micelle formulation NANT-008A nanoparticle-based formulation consisting of polymeric micelles encapsulating the taxane paclitaxel, with...
paclitaxel vitamin E-based emulsion formulationA cremophor-free, P-glycoprotein-inhibiting, vitamin E-based emulsion particle formulation of paclitaxel with...
paclitaxel-conjugated CXCR4 peptide antagonist MB1707A peptide-drug conjugate (PDC) of paclitaxel with an inhibitor of CXC chemokine receptor 4 (CXCR4), with...
paclitaxel-loaded polymeric micelleA form of the anticancer drug paclitaxel used to treat breast cancer, ovarian cancer, and AIDS-related Kaposi...
pacritinib citrateA drug used to treat adults with intermediate-risk or high-risk myelofibrosis (MF), including primary MF...
PADAn abbreviation for a chemotherapy combination used to treat multiple myeloma. It includes the drugs...
PAD regimenAn abbreviation for a chemotherapy combination used to treat multiple myeloma. It includes the drugs...
PadcevA drug used alone or with pembrolizumab to treat adults with certain types of urothelial cancer (a type of...
padeliporfinA vascular-acting photosensitizer consisting of a water-soluble, palladium-substituted bacteriochlorophyll...
PADRE 965.10Pan-DR epitope (PADRE) 965.10 is a helper peptide. PADRE peptides have been shown the capacity to deliver...
PADRE-CMV fusion peptide vaccineA peptide-based vaccine containing a pan HLA DR-binding epitope (PADRE) fused to a cytomegalovirus (CMV)...
pafolacianine sodiumThe sodium salt form of pafolacianine, a fluorescent imaging agent composed of a folate receptor-alpha...
Paget disease of boneA chronic condition in which both the breakdown and regrowth of bone are increased. Paget disease of bone...
Paget disease of the breastA rare type of breast cancer that involves the nipple and, usually, the areola (the darker circle of skin...
Paget disease of the nippleA rare type of breast cancer that involves the nipple and, usually, the areola (the darker circle of skin...
PAHA type of chemical formed when coal, oil, gas, garbage, tobacco, meat, and other substances are burned. These...
PAI-1 inhibitor ACT001The fumarate salt form of the parthenolide derivative micheliolide (MCL), and an orally bioavailable...
pain expressionRefers to the way in which a person shows that he or she is in pain. People can express pain verbally or...
pain flareA sudden increase in pain that may occur in patients who already have chronic pain from cancer, arthritis...
pain thresholdThe point at which a person becomes aware of pain.
PAK4 inhibitor PF-03758309An orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential...
PAK4/NAMPT inhibitor ATG-019An orally bioavailable inhibitor of both the serine/threonine kinase P21-activated kinase 4 (PAK4) and the...
PALAA substance that is being studied for its ability to increase the effectiveness of the anticancer drug...
palacaparibAn orally bioavailable central nervous system (CNS) penetrant and inhibitor of nuclear enzyme...
palateThe roof of the mouth. The front portion is bony (hard palate), and the back portion is muscular (soft...
palatine uvulaThe soft flap of tissue that hangs down at the back of the mouth (at the edge of the soft palate). Also...
palazestrantAn orally available, small molecule antagonist of estrogen receptor alpha (ERalpha; ERa; ESR1; nuclear...
palbociclibA drug used to treat women and men with certain types of hormone-receptor positive, HER2-negative breast...
paliferminA drug used to prevent and treat severe oral mucositis (mouth sores). It is used in patients with blood...
palifosfamideA synthetic mustard compound with potential antineoplastic activity. An active metabolite of ifosfamide...
palifosfamide tromethamineA synthetic mustard compound of the tromethamine (tris) salt of palifosfamide (Isophosphamide mustard), with...
palivizumabA humanized monoclonal antibody against the fusion protein (F protein) of human respiratory syncytial virus...
palladium Pd-103A radioisotope of the metal palladium used in brachytherapy implants or 'seed'. With a half-life of 17 days...
palladium-bacteriopheophorbideA novel palladium-substituted bacteriochlorophyll derivative and photosensitizer with potential antitumor...
palliationRelief of symptoms and suffering caused by cancer and other life-threatening diseases. Palliation helps a...
palliative careCare given to improve the quality of life and help reduce pain in people who have a serious or...
palliative care specialistA health care professional who has special training in providing care to people who have a serious or...
palliative sedationThe use of special drugs called sedatives to relieve extreme suffering by making a patient calm, unaware, or...
palliative therapyTreatment given to help relieve the symptoms and reduce the suffering caused by cancer or other...
palmar pitA tiny dent in the skin on the palm of the hand. Palmar pits are usually pink or skin-colored and can often...
palmar-plantar erythrodysesthesiaA condition marked by pain, swelling, numbness, tingling, or redness of the hands or feet. It sometimes...
palmidrolA natural fatty acid amide that is both a food component and an endogenously synthesized compound, with...
palonosetron hydrochlorideA drug used in adults and children aged 1 month and older to prevent nausea and vomiting caused by...
palpable diseaseA term used to describe cancer that can be felt by touch, usually present in lymph nodes, skin, or other...
palpationExamination by pressing on the surface of the body to feel the organs or tissues underneath.
palpitationA rapid or irregular heartbeat that a person can feel.
PamelorA drug used to treat depression. It may also be used to treat panic or anxiety disorders and certain types of...
pamidronate disodiumA drug used to treat hypercalcemia (high blood levels of calcium) caused by cancer and bone damage caused by...
pamiparibAn orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP), with potential...
pamrevlumabA human monoclonal antibody targeting connective tissue growth factor (CTGF) with potential anti-fibrotic and...
pan FGFR inhibitor PRN1371A highly specific covalent inhibitor of human fibroblast growth factor receptor types 1, 2, 3 and 4 (FGFR1-4)...
panaceaA cure-all.
pan-AKT inhibitor ARQ 751An orally bioavailable pan inhibitor of the serine/threonine protein kinase AKT (protein kinase B) enzyme...
pan-AKT kinase inhibitor GSK690693An aminofurazan-derived inhibitor of Akt kinases with potential antineoplastic activity. Pan-AKT kinase...
Pancoast tumorA type of lung cancer that begins in the upper part of a lung and spreads to nearby tissues such as the ribs...
pancreasA glandular organ located in the abdomen. It makes pancreatic juices, which contain enzymes that aid in...
pancreatectomySurgery to remove all or part of the pancreas. In a total pancreatectomy, part of the stomach, part of the...
pancreaticHaving to do with the pancreas.
pancreatic cancerCancer that forms in the tissues of the pancreas. The pancreas is an organ in the abdomen that helps the body...
pancreatic ductPart of a system of ducts in the pancreas. Pancreatic juices containing enzymes are released into these ducts...
pancreatic ductal adenocarcinomaThe most common type of pancreatic cancer. Pancreatic ductal adenocarcinoma forms in exocrine cells of the...
pancreatic endocrine cancerA rare cancer that forms in islet cells (hormone-making cells) of the pancreas. Islet cells make several...
pancreatic endocrine tumorA tumor that forms in islet cells (hormone-making cells) of the pancreas. Pancreatic endocrine tumors may be...
pancreatic enzymeA protein secreted by the pancreas that aids in the digestion of food.
pancreatic exocrine cancerA cancer that forms in exocrine cells of the pancreas. Exocrine pancreas cells make up the glands and ducts...
pancreatic exocrine tumorA tumor that forms in exocrine cells of the pancreas. Exocrine pancreas cells make up the glands and ducts...
pancreatic function testA test used to measure the ability of the pancreas to respond to a hormone called secretin. Secretin causes...
pancreatic insulin-producing tumorAn abnormal mass that grows in the beta cells of the pancreas that make insulin. Pancreatic insulin-producing...
pancreatic juiceFluid made by the pancreas. Pancreatic juices contain proteins called enzymes that aid in digestion.
pancreatic neuroendocrine tumorA tumor that forms in islet cells (hormone-making cells) of the pancreas. Pancreatic neuroendocrine tumors...
pancreatic polypeptideA small protein made by the pancreas that helps control the release of other substances made by the pancreas...
pancreatic tumorA tumor that forms in the cells of the pancreas. The two main types of pancreatic tumors are pancreatic...
pancreatitisInflammation of the pancreas. Chronic pancreatitis may cause diabetes and problems with digestion. Pain is...
pancreatoduodenectomyA type of surgery used to treat pancreatic cancer. The head of the pancreas, the duodenum, a portion of the...
pancrelipaseA standardized enzyme concentrate containing the pancreatic enzymes, lipase, protease and amylase used in...
pancytopeniaA condition in which there is a lower-than-normal number of red and white blood cells and platelets in the...
pan-DDR DNA decoy-cholesterol conjugate VIO-01A pan-DNA damage response (DDR) DNA decoy linked to a cholesterol molecule, with potential immunomodulatory...
pan-FGFR inhibitor ABSK-121-NXAn orally bioavailable, small molecule pan-inhibitor of fibroblast growth factor receptor (FGFR) family...
pan-FGFR inhibitor LY2874455An orally bioavailable pan-inhibitor of fibroblast growth factor receptor (FGFR) family proteins, with...
pan-FLT3/Pan-BTK multi-kinase inhibitor CG-806An orally bioavailable reversible, pan-inhibitor of both FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2)...
pan-HER inhibitor FCN-411An orally bioavailable pan-human epidermal growth factor receptors (EGFR; HER) tyrosine kinase inhibitor...
pan-HER kinase inhibitor AC480An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626...
pan-HER/VEGFR2 receptor tyrosine kinase inhibitor BMS-690514A pyrrolotriazine-based compound and a pan inhibitor of receptor tyrosine kinases with potential...
panhypopituitarismA rare condition in which the pituitary gland stops making most or all hormones. Pituitary hormones help...
panicSudden extreme anxiety or fear that may cause irrational thoughts or actions. Panic may include rapid heart...
panic disorderA type of anxiety disorder in which a person has repeated panic attacks when there is no actual danger. Panic...
panitumumabA drug used alone or with other drugs to treat certain types of colorectal cancer that have spread to other...
panitumumab-IRDye800An imaging agent composed of panitumumab, a humanized anti-epidermal growth factor receptor (EGFR) monoclonal...
pan-KRAS inhibitor BGB-53038An orally bioavailable inhibitor of KRAS mutations, with potential antineoplastic activity. Upon oral...
pan-KRAS inhibitor BI 1701963An orally available protein-protein interaction (PPI) inhibitor that targets the guanine nucleotide exchange...
pan-KRAS inhibitor PF-07934040An orally bioavailable inhibitor of KRAS mutations, with potential antineoplastic activity. Upon oral...
pan-KRAS inhibitor PF-07985045An orally bioavailable inhibitor of KRAS mutations, with potential antineoplastic activity. Upon oral...
pan-mutant-IDH1 inhibitor BAY1436032An orally available pan-inhibitor of mutant forms of the metabolic enzyme isocitrate dehydrogenase type 1...
pan-mutant-selective PI3K-alpha inhibitor RLY-2608An orally bioavailable, pan-mutant selective inhibitor of the class I phosphatidylinositol-4,5-bisphosphate...
pan-mutant-selective PI3K-alpha inhibitor RLY-5836An orally bioavailable, pan-mutant selective inhibitor of the class I phosphatidylinositol-4,5-bisphosphate...
pan-NOTCH protein-protein interaction inhibitor CB-103An orally bioavailable protein-protein interaction (PPI) inhibitor that targets the assembly of the NOTCH...
panobinostat lactateThe lactate form of panobinostat, a pan histone deacetylase (HDAC) inhibitor, with potential antineoplastic...
panobinostat nanoparticle formulation MTX110A gold nanoparticle (GNP)-based formulation containing panobinostat, a pan histone deacetylase (HDAC)...
pan-PI3K inhibitor CLR457An orally bioavailable pan inhibitor of phosphatidylinositol-3-kinase (PI3K), with potential antineoplastic...
pan-PI3K/mTOR inhibitor SF1126A water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to...
pan-PIM kinase inhibitor AZD1208An orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity. Pan-PIM...
pan-PIM kinase inhibitor GDC-0570An orally available small molecule pan-inhibitor of the PIM serine/threonine kinase family, with potential...
pan-RAF inhibitor JZP815An orally bioavailable inhibitor of all members of the serine/threonine protein kinase Raf family, including...
pan-Raf inhibitor KIN-2787An orally available inhibitor of class I, II, and III B-Raf (BRAF) protein kinases, with potential...
pan-RAF inhibitor LY3009120An orally available inhibitor of all members of the serine/threonine protein kinase Raf family, including...
pan-RAF inhibitor QLH11906An orally bioavailable inhibitor of all members of the serine/threonine protein kinase Raf family, including...
pan-RAF inhibitor XP-102An orally bioavailable, second-generation inhibitor of all members of the serine/threonine protein kinase Raf...
pan-RAF kinase inhibitor CCT3833An orally available inhibitor of the serine/threonine protein kinase family Raf, including A-Raf, B-Raf and...
pan-RAF/MEK molecular glue NST-628An orally bioavailable non-covalent non-degrading pan-RAF/mitogen-activated protein kinase kinase (MAP2K...
pan-selectin antagonist GMI-1070A synthetic, glycomimetic molecule and pan-selectin antagonist, with potential use in a vaso-occlusive...
pan-TEAD inhibitor ISM6331An orally bioavailable non-covalent small molecule inhibitor of the TEA domain (TEAD) family of transcription...
pantoprazole sodiumThe sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole is a...
pantothenic acidA nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy...
pan-TRK inhibitor ICP-723An orally bioavailable, selective pan-tropomyosin-related-kinase (tyrosine receptor kinase; TRK) inhibitor...
pan-TRK inhibitor ONO-75791. An orally bioavailable, selective pan-tropomyosin-related-kinase (tyrosine receptor kinase; TRK)...
pan-TRK inhibitor PBI-200An orally bioavailable, brain-penetrant pan-tropomyosin-related-kinase (tyrosine receptor kinase; TRK)...
pan-TRK/ROS1 dual inhibitor XZP-5955An orally available dual inhibitor of the receptor tyrosine kinase c-ros oncogene 1 (ROS1) and the...
PANVAC-VA cancer vaccine made with a form of vaccinia virus that does not cause disease in humans. It is being...
pan-variant KIT inhibitor THE-630An orally bioavailable pan-inhibitor of the mutated forms of the tumor-associated antigen (TAA) receptor...
pan-VEGFR/TIE2 tyrosine kinase inhibitor CEP-11981An orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR) and Tie2 receptor...
PAPAn enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer...
Pap smearA procedure in which a small brush is used to gently remove cells from the surface of the cervix and the area...
Pap testA procedure in which a small brush is used to gently remove cells from the surface of the cervix and the area...
Papanicolaou testA procedure in which a small brush is used to gently remove cells from the surface of the cervix and the area...
papaverine hydrochlorideThe hydrochloride salt of the opiate alkaloid isolated from the plant Papaver somniferum and produced...
Pap/HPV cotestA procedure in which a human papillomavirus (HPV) test and a Pap test are done at the same time to check for...
papillary dermisThe thin top layer of the dermis (the inner layer of the skin). The papillary dermis has connective tissue...
papillary intralymphatic angioendotheliomaA rare, slow-growing tumor of blood vessels that forms in or under the skin anywhere on the body. Papillary...
papillary kidney cancerA type of kidney cancer that forms in the lining of the tiny tubes in the kidney that return filtered...
papillary renal cell carcinomaA type of kidney cancer that forms in the lining of the tiny tubes in the kidney that return filtered...
papillary serous carcinomaAn aggressive cancer that usually affects the uterus/endometrium, peritoneum, or ovary.
papillary thyroid cancerCancer that forms in follicular cells in the thyroid and grows in small finger-like shapes. It grows slowly...
papillary tumorA tumor that looks like long, thin “finger-like” growths. These tumors grow from tissue that lines the inside...
papillary-reticular dermal interfaceThe layer of the skin between the papillary dermis (the thin top layer of the dermis) and the reticular...
papilledemaSwelling around the optic disk, the area where the optic nerve (the nerve that carries messages from the eye...
PAP/PSA-expressing arenaviral vectors HB-302/HB-301An alternating, 2-vector replicating arenaviral combination agent composed of two genetically engineered...
papuleA small, solid, raised bump on the skin that has a border with edges that are easy to see. Papules may be...
PAR-101A substance being studied in the treatment of diarrhea caused by infection with Clostridium difficile (a type...
para-aminobenzoic acidA nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy...
paracentesisA procedure in which a thin needle or tube is put into the abdomen to remove fluid from the peritoneal cavity...
paragangliaA collection of cells that came from embryonic nervous tissue, and are found near the adrenal glands and some...
paragangliomaA rare, usually benign tumor that develops from cells of the paraganglia. Paraganglia are a collection of...
parageusiaA bad taste in the mouth. Also called dysgeusia.
paralysisLoss of ability to move all or part of the body.
paralytic ileusA condition in which the muscles of the intestines do not allow food to pass through, resulting in a blocked...
parametriumThe fat and connective tissue that surrounds the uterus. The parametrium helps connect the uterus to other...
paramyxovirusA type of virus that has hemagglutinin-neuraminidase proteins in the outer coat and RNA as the genetic...
paranasal sinusOne of many small hollow spaces in the bones around the nose. Paranasal sinuses are named after the bones...
paranasal sinus and nasal cavity cancerCancer that forms in tissues of the paranasal sinuses (small hollow spaces in the bones around the nose) or...
paraneoplastic syndromeA group of symptoms that may develop when substances released by some cancer cells disrupt the normal...
paranoiaA mental disorder in which a person has an extreme fear and distrust of others. A paranoid person may have...
parapharyngeal spaceA triangular area near the pharynx (throat), between the base of the skull and the hyoid bone (the bone under...
parasiteAn animal or plant that gets nutrients by living on or in an organism of another species. A complete parasite...
parasiticHaving to do with or being a parasite (an animal or plant that gets nutrients by living on or in an organism...
parasomniaAn abnormal disruption of sleep, such as sleep walking, sleep talking, nightmares, bedwetting, sleep apnea...
parasympathetic nervous systemThe part of the nervous system that slows the heart, dilates blood vessels, decreases pupil size, increases...
parathormoneA substance made by the parathyroid gland that helps the body store and use calcium. A higher-than-normal...
parathyrinA substance made by the parathyroid gland that helps the body store and use calcium. A higher-than-normal...
parathyroid cancerA rare cancer that forms in tissues of one or more of the parathyroid glands (four pea-sized glands in the...
parathyroid glandOne of four pea-sized glands found on the surface of the thyroid. The parathyroid hormone made by these...
parathyroid hormoneA substance made by the parathyroid gland that helps the body store and use calcium. A higher-than-normal...
parathyroid hormone-related protein (1-36)A recombinant form of a mature, N-terminal secretory peptide derived from a parathyroid hormone-related...
parathyroid hyperplasiaA condition in which the parathyroid glands (four pea-sized glands found in the neck) are larger than normal...
parathyroidectomySurgery to remove one or more parathyroid glands (four pea-sized organs found on the thyroid).
para-toluenesulfonamideA low-molecular-weight organic compound with potential antineoplastic activity. Upon intra-tumoral injection...
parecoxib sodiumA water-soluble, injectable sodium salt form of parecoxib, an amide prodrug of the cyclooxygenase II (COX-2)...
parenchymaThe essential or functional elements of an organ.
parenteral nutritionA form of nutritional support that is given directly into the bloodstream through a catheter placed into a...
paresthesiaAn abnormal touch sensation, such as burning or prickling, that occurs without an outside stimulus.
PARG inhibitor ETX-19477An orally bioavailable, small molecule inhibitor of poly (ADP-Ribose) (PAR) glycohydrolase (PARG), with...
PARG inhibitor IDE161An orally bioavailable, small molecule inhibitor of poly (ADP-Ribose) (PAR) glycohydrolase (PARG), with...
paricalcitolA substance that is being used to treat overactive parathyroid glands in patients with kidney failure. It is...
parietal cell vagotomySurgery to cut the parts of the vagus nerve that cause gastric acid to be made in the stomach. It is done to...
parietal pericardiumThe outer layer of the pericardium, which is a thin sac of tissue that surrounds the heart.
parietal peritoneumThe layers of tissue that line the abdominal wall and the pelvic cavity.
Parkinson diseaseA progressive disorder of the nervous system marked by muscle tremors, muscle rigidity, decreased mobility...
PARN geneA gene that makes a protein involved in controlling gene expression and maintaining telomeres (the ends of...
paromomycin sulfateThe sulfate salt form of paromomycin, a structural derivative of neomycin, an aminoglycoside antibiotic with...
parotid gland cancerCancer that forms in a parotid gland, the largest of the salivary glands, which make saliva and release it...
parotidectomySurgery to remove all or part of the parotid gland (a large salivary gland located in front of and just below...
paroxetine hydrochlorideA drug used to treat depression and anxiety disorders. It is a type of selective serotonin reuptake inhibitor...
paroxysmal nocturnal hemoglobinuriaA rare disorder in which red blood cells are easily destroyed by certain immune system proteins. Symptoms...
PARPA type of enzyme involved in many functions of the cell, including the repair of DNA damage. DNA damage may...
PARP 1/2 inhibitor NOV1401An orally available small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and...
PARP 1/2 inhibitor RP12146An orally bioavailable, small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1...
PARP 1/2 inhibitor SC10914An orally bioavailable inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and 2, with...
PARP 1/2 inhibitor TQB3823An orally bioavailable, small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1...
PARP inhibitorA substance that blocks an enzyme in cells called PARP. PARP helps repair DNA when it becomes damaged. DNA...
PARP inhibitor AZD2281A drug used alone or with other drugs to treat adults with certain types of prostate cancer, pancreatic...
PARP inhibitor AZD2461An orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential...
PARP inhibitor CEP-9722A small-molecule prodrug of CEP-8983, a novel 4-methoxy-carbazole inhibitor of the nuclear enzymes...
PARP inhibitor E7016An inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemo- and/or...
PARP inhibitor NMS-03305293An orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential...
PARP-1An enzyme involved in many functions of the cell, including the repair of DNA damage. DNA damage may be...
PARP-1 inhibitor ABT-888A substance being studied in the treatment of breast cancers caused by mutations (changes) in the BRCA1 and...
PARP1 inhibitor ACE-86225106An orally bioavailable inhibitor of nuclear enzyme poly(ADP-ribose) polymerase (PARP) 1, with potential...
PARP-1 inhibitor AG014699A drug used to treat adults with certain types of prostate cancer or ovarian epithelial, fallopian tube, or...
PARP1 inhibitor GS-0201An orally bioavailable inhibitor of nuclear enzyme poly(ADP-ribose) polymerase (PARP) 1, with potential...
PARP1 inhibitor HRS-1167An orally bioavailable inhibitor of nuclear enzyme poly(ADP-ribose) polymerase (PARP) 1, with potential...
PARP1 inhibitor HS-10502An orally bioavailable inhibitor of nuclear enzyme poly(ADP-ribose) polymerase (PARP) 1, with potential...
PARP1 inhibitor IMP1734An orally bioavailable inhibitor of nuclear enzyme poly(ADP-ribose) polymerase (PARP) 1, with potential...
PARP1 inhibitor SNV1521An orally bioavailable inhibitor of nuclear enzyme poly(ADP-ribose) polymerase (PARP) 1, with potential...
PARP-1/2 inhibitor ABT-767An orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with...
PARP7 inhibitor BY101921An orally available inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) 7, with potential...
PARP/microtubule polymerization inhibitor AMXI-5001An orally bioavailable, dual inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and 2 and...
PARP/tankyrase inhibitor 2X-121An orally available small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and...
parsaclisibAn inhibitor of the delta isoform of phosphoinositide-3 kinase (PI3K) with potential antineoplastic activity...
parsatuzumabA humanized IgG1 monoclonal antibody directed against the epidermal growth factor-like domain multiple 7...
partial cystectomySurgery to remove part of the bladder (the organ that holds urine). Also called segmental cystectomy.
partial hysterectomySurgery to remove the uterus, but not the cervix. Also called subtotal hysterectomy and supracervical...
partial laryngectomyAn operation to remove part of the larynx (voice box).
partial mastectomySurgery to remove cancer or other abnormal tissue from the breast and some normal tissue around it, but not...
partial nephrectomySurgery to remove part of one kidney or a kidney tumor, but not an entire kidney.
partial oophorectomySurgery to remove part of one ovary or part of both ovaries.
partial parenteral nutritionA form of short-term nutritional support that is given directly into the bloodstream through a catheter...
partial radical vulvectomySurgery to remove most, but not all, of the vulva (the external female genital organs, including the...
partial remissionA decrease in the size of a tumor, or in the extent of cancer in the body, in response to treatment. Also...
partial responseA decrease in the size of a tumor, or in the extent of cancer in the body, in response to treatment. Also...
partial vulvectomySurgery to remove an affected area of the vulva (the external female genital organs, including the clitoris...
partial-breast irradiationA type of radiation therapy given only to the part of the breast that has cancer in it. Partial-breast...
partially engineered T-regulatory cell donor graft TRGFT-201A T-regulatory (Treg) cell donor graft that has been partially engineered by depleting all the T cells and...
partially HLA-matched AdV/CMV/EBV-specific allogeneic T lymphocytesPartially or closely human leukocyte antigen (HLA)-matched allogeneic cytotoxic T lymphocytes (CTLs), derived...
partially HLA-matched multiple TAA-specific allogeneic T lymphocytesA preparation of partially human leukocyte antigen (HLA)-matched allogeneic T lymphocytes targeting multiple...
parvovirus H-1A replication-competent oncolytic parvovirus with potential antineoplastic activity. Upon infection of host...
pasireotideA synthetic long-acting cyclic peptide with somatostatin-like activity. Pasireotide activates a broad...
pasotuxizumabA recombinant T-cell engaging bispecific monoclonal antibody (BiTE) directed against human prostate specific...
passive antibody therapyTreatment with injections of antibodies made in another animal or in the laboratory.
passive immunityA type of immunity that occurs when a person is given antibodies rather than making them through his or her...
pastoral counselorA person who is trained to give spiritual and mental health advice.
patchouliA bushy herb that is a member of the mint family. A strong-smelling oil taken from the leaves is used in...
patent blue V dyeA synthetic dye with imaging and food coloring property. It is a sodium or calcium salt of...
paternalHaving to do with the father, coming from the father, or related through the father.
Paterson-Kelly syndromeA disorder marked by anemia caused by iron deficiency, and a web-like growth of membranes in the throat that...
pathogenic variantA change in the DNA sequence of a gene that causes a person to have or be at risk of developing a certain...
pathognomonicHaving to do with a sign or symptom that is specific to a certain disease.
pathologic complete remissionThe lack of all signs of cancer in tissue samples removed during surgery or biopsy after treatment with...
pathologic complete responseThe lack of all signs of cancer in tissue samples removed during surgery or biopsy after treatment with...
pathologic diagnosisIdentifying a disease or condition by examining cells and tissues under a microscope. In cancer, a pathologic...
pathologic fractureA broken bone caused by disease, often by the spread of cancer to the bone.
pathological stageThe stage of cancer (amount or spread of cancer in the body) that is based on how different from normal the...
pathological stagingA method used to find out the stage of cancer (amount or spread of cancer in the body) by removing tissue...
pathologistA doctor who has special training in identifying diseases by studying cells and tissues under a microscope.
pathology reportThe description of cells and tissues made by a pathologist based on microscopic evidence, and sometimes used...
patidegibAn orally bioavailable, cyclopamine-derived inhibitor of the Hedgehog (Hh) pathway with potential...
patidegib topical gelA topical gel containing patidegib, a cyclopamine-derived inhibitor of the Hedgehog (Hh) pathway, with...
patient advocateA person who helps guide a patient through the health care system. This includes help going through the...
patient care costsThe costs related to the treatment of a disease, such as cancer. These costs include doctor visits, hospital...
patient navigatorA person who helps guide a patient through the health care system. This includes help going through the...
patient-controlled analgesiaA method of pain relief in which the patient controls the amount of pain medicine that is used. When pain...
patient-derived xenograftTumor tissue that has been taken from a patient and implanted into mice for research purposes. Cancer drugs...
patient-reported outcomeInformation about a patient’s health that comes directly from the patient. Examples of patient-reported...
patritumabA fully human monoclonal antibody directed against the membrane-bound receptor HER3 (ERBB3) with potential...
patritumab deruxtecanAn antibody-drug conjugate (ADC) composed of patritumab, a monoclonal antibody directed against the human...
patupiloneA compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces...
pavunalimabAn Fc-engineered bispecific antibody directed against the human negative immunoregulatory checkpoint...
pavurutamabA bispecific T-cell engager (BiTE) antibody composed of two single-chain variable fragments (scFv), one...
paxalisibA phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. paxalisib...
PaxilA drug used to treat depression and anxiety disorders. It is a type of selective serotonin reuptake inhibitor...
pazopanib hydrochlorideA drug used to treat adults with advanced renal cell carcinoma (a type of kidney cancer) or advanced soft...
pBCAR3 phosphopeptide-tetanus peptide vaccineA vaccine composed of a phosphorylated peptide from the tumor-associated antigen breast cancer anti-estrogen...
pBCAR3/pIRS2-phosphopeptide-tetanus peptide vaccineA vaccine composed of phosphorylated peptides from the tumor associated antigens breast cancer anti-estrogen...
pbi-shRNA STMN1 lipoplexA proprietary RNA interference construct consisting of bifunctional short hairpin RNAs (shRNA) against human...
PBSCTA procedure in which a patient receives healthy blood-forming cells (stem cells) to replace their own stem...
PC regimenA chemotherapy combination used to treat endometrial, ovarian, and head and neck cancers, and non-small cell...
PCAA method of pain relief in which the patient controls the amount of pain medicine that is used. When pain...
PCA3 mRNA testA laboratory test that measures the amount of genetic material called PCA3 mRNA and PSA mRNA in the first...
p-cadherin antagonist PF-03732010An agent that inhibits p-cadherin (cdh3), with potential antineoplastic activity. PF-03732010 binds to and...
P-cadherin inhibitor PCA062An agent that inhibits p-cadherin, with potential antineoplastic activity. Upon intravenous infusion, PCA062...
P-cadherin-targeting agent PF-06671008An agent that targets p-cadherin (CDH3), with potential antineoplastic activity. Upon administration...
PCBOne of a large group of man-made chemical compounds that were used to make many products, including...
PCNA inhibitor AOH1996An orally bioavailable, small molecule inhibitor of proliferating cell nuclear antigen (PCNA), with potential...
PCNSLPrimary CNS lymphoma. Cancer that forms in the lymph tissue of the brain, spinal cord, meninges (outer...
PCOSA condition marked by infertility, enlarged ovaries, menstrual problems, high levels of male hormones, excess...
PCPA doctor or other licensed medical professional, such as a nurse practitioner or physician assistant, who...
PCRA laboratory method used to make many copies of a specific piece of DNA from a sample that contains very tiny...
PC-SPESA mixture of eight herbs that has been sold as a dietary supplement and promoted as a way to keep the...
PCTA rare disorder that affects the skin and causes painful blisters on parts of the body that are exposed to...
PCVAn abbreviation for a chemotherapy combination used to treat certain types of brain tumors. It is often used...
PCV regimenAn abbreviation for a chemotherapy combination used to treat certain types of brain tumors. It is often used...
PD-1A protein found on T cells (a type of immune cell) that helps keep the body’s immune responses in check. When...
PD-1 knockout autologous T lymphocytesA population of engineered autologous T lymphocytes in which the gene encoding for the programmed cell death...
PD-1 knockout EBV-specific cytotoxic T lymphocytesA preparation of Epstein-Barr virus (EBV) reactive cytotoxic T lymphocytes (CTLs) in which the programmed...
PD-1 targeted IL-2 mutein fusion protein KY-0118A fusion protein comprised of a human negative immunoregulatory checkpoint receptor programmed cell death...
PD-1-directed probody CX-188A probody composed of a monoclonal antibody directed against the negative immunoregulatory human cell surface...
PD-1-targeted IL-15 mutein fusion protein PF-07209960A fusion protein composed of a moiety targeting the negative immunoregulatory human cell receptor programmed...
PD-1-targeted IL-2 variant antibody fusion protein RO7284755A recombinant fusion protein comprised of an antibody directed against the human negative immunoregulatory...
PDACThe most common type of pancreatic cancer. PDAC forms in exocrine cells of the pancreas. Exocrine pancreas...
PDGFA family of molecules released from platelets (tiny pieces of cells that are found in the blood and that help...
PDGFRA geneA gene that makes a protein that is involved in cell division and cell survival. Mutated (changed) forms of...
PDK1 inhibitor AR-12An orally bioavailable, small-molecule, celecoxib-derived inhibitor of phosphoinositide-dependent kinase-1...
PD-L1A protein that acts as a kind of “brake” to keep the body’s immune responses under control. PD-L1 may be...
PD-L1 inhibitor ABSK043An orally available, small molecule inhibitor of the immunosuppressive ligand programmed cell death-1 ligand...
PD-L1 inhibitor BPI-371153An orally bioavailable, small molecule inhibitor of the immunosuppressive ligand programmed cell death-1...
PD-L1 inhibitor GS-4224An orally available, small molecule inhibitor of the immunosuppressive ligand programmed cell death-1 ligand...
PD-L1 inhibitor INCB086550An orally available, small molecule inhibitor of the immunosuppressive ligand, programmed cell death-1 ligand...
PD-L1 inhibitor INCB099280An orally bioavailable, small molecule inhibitor of the immunosuppressive ligand programmed cell death-1...
PD-L1 inhibitor INCB099318An orally available, small molecule inhibitor of the immunosuppressive ligand programmed cell death-1 ligand...
PD-L1 peptide vaccineA vaccine composed of a peptide derived from the tumor-associated antigen (TAA) and immune checkpoint...
PD-L1/4-1BB/HSA trispecific fusion protein NM21-1480A recombinant, trispecific monovalent antibody-based molecule targeting the human programmed death-ligand 1...
PD-L1/IDO peptide vaccine IO102-103A peptide vaccine composed of IO103, a peptide vaccine derived from the tumor-associated antigen (TAA)...
PD-L1/PD-L2 peptide-Montanide vaccineA vaccine composed of peptides derived from the immune checkpoint molecules, programmed death ligand 1...
PD-L1/PD-L2/VISTA antagonist CA-170An orally bioavailable small molecule inhibitor of the immune checkpoint regulatory proteins programmed cell...
PD-L2 peptide-Montanide vaccineA vaccine composed of a peptide derived from the immune checkpoint molecule programmed death ligand 2 (PD-L2)...
pDNA-encoding Emm55 autologous cancer cell vaccine IFx-Hu2.0A whole cell cancer vaccine composed of irradiated autologous whole tumor cells that are transfected, ex...
p.DOM-WT1-126 DNA vaccineA fusion DNA vaccine containing the first domain of fragment C (FrC) of tetanus toxin (TT865-1120) (p.DOM)...
p.DOM-WT1-37 DNA vaccineA fusion DNA vaccine containing the first domain of fragment C (FrC) of tetanus toxin (TT865-1120) (p.DOM)...
PDQPDQ is an online source of cancer information that is developed and maintained by the National Cancer...
PDXTumor tissue that has been taken from a patient and implanted into mice for research purposes. Cancer drugs...
peak exposureThe largest amount of a substance or radiation that a person is exposed to at one time. Peak exposure to a...
peau d'orangeA dimpled condition of the skin of the breast, resembling the skin of an orange, sometimes found in...
PEBAn abbreviation for a chemotherapy combination used in children to treat certain types of malignant (cancer)...
PEB regimenAn abbreviation for a chemotherapy combination used in children to treat certain types of malignant (cancer)...
PEComaA family of rare tumors that form in the soft tissues of the stomach, intestines, lungs, female reproductive...
PediaSureA nutritional drink that helps children who cannot get everything they need in their diet from foods and...
pediatricHaving to do with children.
pediatric cancerA term used to describe cancers that occur between birth and 14 years of age. Pediatric cancers are very rare...
pediatric gastroenterologistA doctor who has special training in diagnosing and treating disorders of the gastrointestinal (digestive)...
pediatric hematologistA doctor who has special training in diagnosing and treating blood disorders in children.
pediatric intensivistA doctor who has special training in diagnosing and treating children who are seriously ill or injured...
pediatric nurse specialistA registered nurse with an advanced degree in nursing who specializes in the care of children.
pediatric oncologistA doctor who has special training in diagnosing and treating children with cancer.
pediatric polymeric enteral nutrition formulaA nutritional drink that helps children who cannot get everything they need in their diet from foods and...
pediatric surgeonA surgeon who has special training in treating children. A surgeon removes or repairs a part of the body by...
pediatricianA doctor who has special training in preventing, diagnosing, and treating diseases and injuries in children...
pedicle flapA type of surgery used to rebuild the shape of the breast after a mastectomy. Tissue, including skin, fat...
pedigreeA diagram that shows relationships among family members. In medicine, a pedigree may also show the pattern of...
PedmarkA drug used to reduce the risk of hearing loss in children aged 1 month and older who are receiving cisplatin...
pedunculatedIn the body, a structure that has a peduncle (a stalk or stem) or is attached to another structure by a...
peer review processThe process by which original articles and grants written by researchers are evaluated for technical and...
peer-reviewed scientific journalA publication that contains original articles that have been written by scientists and evaluated for...
PEGA polymer made by joining molecules of ethylene oxide and water together in a repeating pattern. PEG can be a...
PEG tubeA tube inserted through the wall of the abdomen directly into the stomach. It allows air and fluid to leave...
PEG-3350/sodium sulfate/sodium chloride/potassium chloride/sodium ascorbate/ascorbic acid-based laxativeA preparation containing the nonabsorbable polymer polyethylene glycol (PEG or macrogol) 3350 and sodium...
PEG4000/simethicone/sodium sulphate/sodium bicarbonate/electrolytes oral solutionA powder for orF3:J23tion containing polyethylene glycol (PEG) 4000 (macrogol 4000), simethicone, sodium...
pegargiminaseAn agent consisting of the arginine-degrading enzyme arginine deiminase combined with polyethylene glycol...
PEG-asparaginaseA drug used with other drugs to treat adults and children with acute lymphoblastic leukemia. It is used in...
pegaspargaseA drug used with other drugs to treat adults and children with acute lymphoblastic leukemia. It is used in...
PegasysA drug used to treat hepatitis C infections. It is also being studied in the treatment and prevention of...
PEG-based laxative NER1006A preparation containing the nonabsorbable polymer polyethylene glycol (PEG or macrogol) 3350 with laxative...
pegcetacoplanA pegylated peptide inhibitor of human complement components C3 and C3b, with potential use as a treatment...
PEG-conjugated TLR7/8 agonist NKTR-262A formulation composed of an agonist of toll-like receptor (TLR) type 7 and 8 (TLR7/8) that is attached to...
pegcrisantaspaseA recombinant, pegylated form of Erwinia asparaginase (crisantaspase), derived from the bacterium Erwinia...
pegdinetanibA highly specific, synthetic peptide vascular endothelial growth factor receptor-2 (VEGFR-2) antagonist with...
pegenzileukinA pegylated recombinant, engineered variant of cytokine interleukin-2 (IL-2; IL2) where novel amino acid is...
pegfilgrastimA drug that is a form of filgrastim and is used to prevent infection in adults and children with neutropenia...
pegfilgrastim anti-neutropenic factorA long-acting, engineered and pegylated version of human granulocyte-colony stimulating factor (G-CSF), with...
pegfilgrastim biosimilar LA-EP2006A biosimilar of pegfilgrastim, a long-acting pegylated form of recombinant human granulocyte...
pegilodecakinA covalent conjugate of recombinant human interleukin-10 (IL-10) and polyethylene glycol (PEG), with...
peginterferon alfa-2aA drug used to treat hepatitis C infections. It is also being studied in the treatment and prevention of...
peginterferon alfa-2bA drug that is no longer available in the United States that was used under the brand name Sylatron to...
PEG-interleukin-2A complex of polyethylene glycol conjugated with human recombinant cytokine interleukin-2 (IL-2) with...
PEG-IntronA drug that is no longer available in the United States that contains the active ingredient peginterferon...
pegipanerminA pegylated, human, engineered dominant-negative tumor necrosis factor (TNF; TNF-alpha) variant devoid of TNF...
pegloticaseA recombinant modified mammalian urate oxidase (uricase) conjugated to monomethoxypolyethylene glycol (mPEG)...
PEG-MGDFA form of megakaryocyte growth and development factor (MGDF) that is made in the laboratory. MGDF comes from...
PEG-modified/site-mutated IL-2 SHR-1916A polyethylene glycol (PEG)-modified and site-mutated form of the cytokine interleukin-2 (IL-2), with...
pegol sihematideA synthetic peptide derived from erythropoietin (EPO) linked to polyethylene glycol (PEG), with...
PEG-PEI-cholesterol lipopolymer-encased IL-12 DNA plasmid vector IMNN-001A nanoparticle-based formulation composed of a non-viral plasmid DNA vector encoding the human...
PEG-rhMGDFA form of megakaryocyte growth and development factor (MGDF) that is made in the laboratory. MGDF comes from...
pegsitacianineA micellar polymer tracer labeled with the near-infrared (NIR) fluorescent imaging dye indocyanine green...
pegteograstimAn analogue of pegfilgrastim, a recombinant, pegylated form of endogenous human granulocyte...
pegtomarginaseA genetically modified form of human enzyme arginase (ARG) site-specifically linked with a linear 20 kDa...
pegvisomantA pegylated, recombinant, human growth hormone (GH) structural analog with GH receptor antagonist activity...
pegylated arginine deiminaseA substance being studied in the treatment of melanoma, liver cancer, and other types of cancer. It breaks...
pegylated CD25/CD122-selective interleukin-2 mutein STK-012A pegylated, engineered variant form of the human cytokine interleukin 2 (IL-2; IL2), with selective binding...
pegylated deoxycytidine analogue DFP-14927A pegylated formulation containing DFP-10917, an analogue of the nucleoside deoxycytidine, with potential...
pegylated granulocyte colony stimulating factor MAXY-G34A long-acting, pegylated recombinant variant of human granulocyte colony-stimulating factor (G-CSF) with...
pegylated IL-2 8MW2311A polyethylene glycol (PEG)-conjugated form of the cytokine interleukin-2 (IL-2), with potential...
pegylated interferon alfaA covalent conjugate of recombinant interferon alpha and polyethylene glycol (PEG), used as an antiviral and...
pegylated liposomal doxorubicin hydrochlorideA liposome-encapsulated preparation of the hydrochloride salt of the anthracycline antineoplastic antibiotic...
pegylated liposomal irinotecanA formulation of polyethylene glycol (PEG)-modified liposomes encapsulating the semisynthetic derivative of...
pegylated liposomal mitomycin C lipid-based prodrugA pegylated liposomal formulation comprised of a lipophilic prodrug of the antineoplastic antibiotic...
pegylated liposomal mitoxantrone hydrochlorideA pegylated liposomal mitoxantrone formulation composed of the hydrochloride salt form of the anthracenedione...
pegylated orthogonal IL-2 STK-009A polyethylene glycol (PEG)-conjugated mutein form of the cytokine interleukin-2 (IL-2), with potential and...
pegylated recombinant human arginase I BCT-100A recombinant human arginase I (liver arginase) covalently attached, via a succinamide propionic acid (SPA)...
pegylated recombinant human hyaluronidase PH20A pegylated formulation of a recombinant form of human hyaluronidase with potential antitumor activity. Upon...
pegylated SN-38 conjugate PLX038A pegylated conjugate of SN-38 (7-ethyl-10-hydroxy-camptothecin), a biologically active metabolite of the...
pegylated TOP1 inhibitor PEEL-224A pegylated camptothecin derivative, with potential antineoplastic activity. Upon administration of pegylated...
pegzerepoetin alfaA pegylated form of recombinant human erythropoietin, a glycosylated protein naturally produced in the kidney...
pegzilarginaseA recombinant modified form of the human enzyme arginase 1 (ARG1), in which cobalt is substituted for...
PE/HPV16 E7/KDEL fusion protein/GPI-0100 TVGV-1A vaccine composed of a lyophilized fusion protein consisting of a peptide sequence of human papillomavirus...
PEIAn injection of ethanol (alcohol) through the skin directly into a tumor to kill cancer cells. Ultrasound or...
PEITCA substance being studied in the prevention of cancer. It is a naturally occurring compound found in some...
pelabresib anhydrousThe anhydrous form of pelabresib, a small molecule inhibitor of the Bromodomain and Extra-Terminal (BET)...
pelareorepAn isolate of the oncolytic, human wild-type serotype 3 Dearing (T3D) strain of the double-stranded RNA virus...
pelargoniumA type of plant that is native to southern Africa and has white, pink, purple, or red flowers and 3- to...
pelcitoclaxA Bcl-2 homology (BH)-3 mimetic and selective inhibitor of the anti-apoptotic proteins B-cell lymphoma 2...
peldesineA substance that is being studied for the treatment of cancer.
pelecopanAn orally bioavailable inhibitor of complement factor D (FD; CFD), a serine protease that cleaves complement...
pelitinibA substance being studied in the treatment of some types of cancer. It blocks the action of certain proteins...
pelitrexolA water soluble antifolate with anti-proliferative activity. Pelitrexol inhibits activity of glycinamide...
pelvicHaving to do with the pelvis. The pelvis is the area of the body below the abdomen that is located between...
pelvic examA physical exam of the vulva, vagina, cervix, uterus, fallopian tubes, ovaries, and rectum. First, the vulva...
pelvic exenterationSurgery to remove the lower colon, rectum, and bladder, and create stomata (openings) through which urine and...
pelvic inflammatory diseaseA condition in which the female reproductive organs are inflamed. It may affect the uterus, fallopian tubes...
pelvic lymph nodeA lymph node in the pelvis. The pelvis is the area of the body below the abdomen that contains the hip bones...
pelvic lymphadenectomySurgery to remove lymph nodes in the pelvis for examination under a microscope to see if they contain cancer.
pelvic wallThe muscles and ligaments that line the part of the body between the hips.
pelvisThe bones between the lower abdomen and upper thighs that connect the spine to the legs. The pelvis supports...
PemazyreA drug used to treat adults with certain types of cholangiocarcinoma (bile duct cancer), myeloid cancer, or...
pembrolizumabA drug that binds to the protein PD-1 to help immune cells kill cancer cells better and is used to treat many...
pembrolizumab/quavonlimab MK-1308AA combination formulation containing fixed doses of the two monoclonal antibodies pembrolizumab and...
pemetrexed disodiumA drug used alone or with other drugs to treat certain types of non-small cell lung cancer and malignant...
PemfexyA drug used alone or with other drugs to treat certain types of non-small cell lung cancer and malignant...
pemigatinibA drug used to treat adults with certain types of cholangiocarcinoma (bile duct cancer), myeloid cancer, or...
penclomedineA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
penectomySurgery to remove part or all of the penis (an external male reproductive organ).
penetranceDescribes how likely it is that a person who has a certain disease-causing mutation (change) in a gene will...
penicillamineA drug that removes copper from the body and is used to treat diseases in which there is an excess of copper...
penicillinA drug that is used to treat infection. It belongs to the family of drugs called antibiotics.
penicillin V potassiumThe potassium salt of penicillin V, a member of the penicillin antibiotic family with broad-spectrum...
penile cancerA rare cancer that forms in the penis (an external male reproductive organ). Most penile cancers are squamous...
penile implantA firm rod or inflatable device that is placed in the penis (an external male reproductive organ) during a...
penisAn external male reproductive organ. It contains a tube called the urethra, which carries semen and urine to...
penpulimabA drug used alone or with other drugs to treat certain types of nasopharyngeal cancer (a type of head and...
penpulimab-kcqxA monoclonal antibody directed against the negative immunoregulatory human cell receptor programmed cell...
PentamA drug used to treat infections caused by certain microorganisms. It is also being studied in the treatment...
pentamethylmelamineA principal metabolite of hexamethylmelamine with antineoplastic activity. Pentamethylmelamine alkylates DNA...
pentamidineA synthetic derivative of amidine with antiprotozoal and antifungal activities. Although the precise mode of...
pentamidine isethionateA drug used to treat infections caused by certain microorganisms. It is also being studied in the treatment...
pentavalent KLH conjugate vaccineA pentavalent vaccine comprised of the epitope antigens of the ganglioside lactones GD2L and GD3L, Globo H...
pentetic acid calciumA drug that protects healthy tissues from the toxic effects of anticancer drugs.
pentosan polysulfateA drug used to relieve pain or discomfort associated with chronic inflammation of the bladder. It is also...
pentosan polysulfate sodiumThe sodium salt of a semisynthetic heparin-like glucosaminoglycan. Although its mechanism of action is...
pentostatinThe active ingredient in a drug that is used to treat hairy cell leukemia and is being studied in the...
pentoxifyllineA drug used to prevent blood clotting and as a treatment that may help decrease weight loss in people with...
PEOX-based polymer encapsulated paclitaxel FID-007A nanoparticle-based formulation composed of the poorly water-soluble paclitaxel encapsulated within branched...
PEP02A form of the anticancer drug irinotecan hydrochloride that is contained inside very tiny, fat-like particles...
PEP-3-KLH conjugate vaccineA cancer vaccine consisting of PEP-3, a synthetic peptide encompassing a tumor-specific mutated segment of...
PEP-CMV vaccineA peptide vaccine derived from cytomegalovirus (CMV) antigens with potential immunostimulating activity...
pepinemabA humanized IgG4 monoclonal antibody against the semaphorin 4D (SEMA4D; CD100) with potential...
peplomycinA semisynthetic analog of Bleomycin, a mixture of several basic glycopeptide antineoplastic antibiotics...
peposertibAn orally bioavailable inhibitor of DNA-dependent protein kinase (DNA-PK) with potential antineoplastic...
peppermint oilThe essential oil extracted from the leaves of Mentha x piperita. Peppermint oil is used for its aromatic...
peppermint oil-containing enteric-coated microspheresA formulation composed of enteric-coated, sustained-release (SR) microspheres containing ultrapurified...
pepsinAn enzyme made in the stomach that breaks down proteins in food during digestion. Stomach acid changes a...
pepsinogenA substance made by cells in the stomach. Acid in the stomach changes pepsinogen to pepsin, which breaks down...
peptic ulcerA break in the lining of the lower part of the esophagus, the stomach, or the upper part of the small...
peptideA molecule that contains two or more amino acids (the molecules that join together to form proteins)...
peptide 946A piece of a protein found only on melanoma (a type of skin cancer) cells. It is being used in vaccines to...
peptide drug conjugate OPD5A peptide-drug conjugate (PDC) composed of a peptide conjugated, via an aminopeptidase-targeting linkage, to...
peptide receptor radionuclide therapyA type of radiation therapy used to treat certain types of neuroendocrine tumors. A radioactive chemical is...
peptidoglycan complex of spirulina K-001An orally bioavailable preparation of peptidoglycan derived from the fermentation product of the marine...
perampanelAn orally active, non-competitive, and selective alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid...
percutaneousPassing through the skin, as an injection or a topical medicine.
percutaneous endoscopic tubeA tube inserted through the wall of the abdomen directly into the stomach. It allows air and fluid to leave...
percutaneous epididymal sperm aspirationA procedure in which a sample of sperm cells is removed from the epididymis through a small needle attached...
percutaneous ethanol injectionAn injection of ethanol (alcohol) through the skin directly into a tumor to kill cancer cells. Ultrasound or...
percutaneous transhepatic biliary drainageA procedure to drain bile to relieve pressure in the bile ducts caused by a blockage. An x-ray of the liver...
percutaneous transhepatic cholangiodrainageA procedure to drain bile to relieve pressure in the bile ducts caused by a blockage. An x-ray of the liver...
percutaneous transhepatic cholangiographyA procedure to x-ray the hepatic and common bile ducts. A contrasting agent is injected through the skin into...
peretinoinAn orally available, acyclic retinoid with potential antineoplastic and chemopreventive activities...
perflenapent emulsionAn oil-in-water nano-emulsion composed of the perfluorocarbon perflenapent, that has oxygen-carrying...
perflubronA synthetic radiopaque liquid form of perfluorooctyl bromide. Used as a contrast agent for magnetic resonance...
perflutrenA fluorinated hydrocarbon and gaseous substance used as an imaging contrast agent. After administration in...
perflutren lipid microspheresAn injectable suspension of liposome-encapsuled microspheres containing the fluorocarbon gas perflutren for...
perflutren protein-type A microspheresA sterile non-pyrogenic suspension of microspheres of human serum albumin with the stable...
performance statusA measure of how well a patient is able to perform ordinary tasks and carry out daily activities.
perfosfamideThe active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and...
perfusionBathing an organ or tissue with a fluid. In regional perfusion, a specific area of the body (usually an arm...
perfusion magnetic resonance imagingA special type of magnetic resonance imaging (MRI) that uses an injected dye in order to see blood flow...
periampullary cancerA cancer that forms near the ampulla of Vater (an enlargement of the ducts from the liver and pancreas where...
pericardial effusionA condition in which extra fluid collects between the heart and the pericardium (the sac around the heart)...
pericardial tamponadeA serious condition that occurs when extra fluid or blood builds up in the space between the heart and the...
pericarditisA condition in which the pericardium (the sac around the heart) becomes inflamed. Pericarditis is usually...

1,454 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.