MLchartDataset catalogue

perfosfamide

Term · Oncology and biomedicine · MLC-T-ONC-015966

The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis.

Table 1. Record
IdentifierMLC-T-ONC-015966
FieldOncology and biomedicine
Abbreviation4-HC
Synonymshydroperoxycyclophosphamide
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-015966",
  "term": "perfosfamide",
  "field": "Oncology and biomedicine",
  "definition": "The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis.",
  "abbreviation": "4-HC",
  "synonyms": [
    "hydroperoxycyclophosphamide"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/perfosfamide/"
}

Record 12,959 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.