MLchartDataset catalogue

imidazole mustard

Term · Oncology and biomedicine · MLC-T-ONC-014372

A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis.

Table 1. Record
IdentifierMLC-T-ONC-014372
FieldOncology and biomedicine
AbbreviationBIC
SynonymsHN2; TIC mustard
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-014372",
  "term": "imidazole mustard",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis.",
  "abbreviation": "BIC",
  "synonyms": [
    "HN2",
    "TIC mustard"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/imidazole-mustard/"
}

Record 9,050 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.