MLchartDataset catalogue

Aniline mustard

Term · Oncology and biomedicine · MLC-T-ONC-010091

An alkylating mustard with antineoplastic activity. Aniline mustard forms covalent linkages with nucleophilic centers, resulting in depurination, base miscoding and strand scission, and crosslinking of DNA strands, all of which contribute to its cytotoxicity.

Table 1. Record
IdentifierMLC-T-ONC-010091
FieldOncology and biomedicine
Synonymslymphochin; lymphocin; lymphoquin; mesylerythrol
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-010091",
  "term": "Aniline mustard",
  "field": "Oncology and biomedicine",
  "definition": "An alkylating mustard with antineoplastic activity. Aniline mustard forms covalent linkages with nucleophilic centers, resulting in depurination, base miscoding and strand scission, and crosslinking of DNA strands, all of which contribute to its cytotoxicity.",
  "synonyms": [
    "lymphochin",
    "lymphocin",
    "lymphoquin",
    "mesylerythrol"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/aniline-mustard/"
}

Record 1,135 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.