sarCNU

{
  "id": "MLC-T-ONC-007550",
  "term": "sarCNU",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance being studied in the treatment of cancer. It is a type of alkylating agent. Also called sarcosinamide nitrosourea.",
    "An alkylating chloroethylnitrosourea with antineoplastic activity. Selectively accumulating in some tumor cells, SarCNU forms covalent linkages with nucleophilic centers in DNA, causing depurination, base pair miscoding, strand scission, and DNA-DNA cross-linking, which may result in cytotoxicity."
  ],
  "expansions": [
    "sarcosinamide nitrosourea"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/sarcnu/"
}